Search Results - "Martins dos Santos, Vitor A. P."
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Genome-Scale Metabolic Network Analysis of the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
Published in Journal of Bacteriology (01-04-2008)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification and functional characterization of novel xylose transporters from the cell factories Aspergillus niger and Trichoderma reesei
Published in Biotechnology for biofuels (20-07-2016)“…Global climate change and fossil fuels limitations have boosted the demand for robust and efficient microbial factories for the manufacturing of bio-based…”
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More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes
Published in Microbiome (14-07-2017)“…The human gut is colonized with a myriad of microbes, with substantial interpersonal variation. This complex ecosystem is an integral part of the…”
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SyNDI: synchronous network data integration framework
Published in BMC bioinformatics (06-11-2018)“…Systems biology takes a holistic approach by handling biomolecules and their interactions as big systems. Network based approach has emerged as a natural way…”
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Tailoring and optimizing fatty acid production by oleaginous yeasts through the systematic exploration of their physiological fitness
Published in Microbial cell factories (03-11-2022)“…Abstract Background The use of palm oil for our current needs is unsustainable. Replacing palm oil with oils produced by microbes through the conversion of…”
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Neochloris oleoabundans is worth its salt: Transcriptomic analysis under salt and nitrogen stress
Published in PloS one (13-04-2018)“…Neochloris oleoabundans is an oleaginous microalgal species that can be cultivated in fresh water as well as salt water. Using salt water gives the opportunity…”
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Phenotype and multi-omics comparison of Staphylococcus and Streptococcus uncovers pathogenic traits and predicts zoonotic potential
Published in BMC genomics (04-02-2021)“…Staphylococcus and Streptococcus species can cause many different diseases, ranging from mild skin infections to life-threatening necrotizing fasciitis. Both…”
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The metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single- and multiple-nutrient-limited growth: highlights from a multi-level omics approach
Published in Microbial cell factories (20-03-2012)“…Pseudomonas putida KT2442 is a natural producer of polyhydroxyalkanoates (PHAs), which can substitute petroleum-based non-renewable plastics and form the basis…”
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Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism
Published in BMC bioinformatics (29-11-2021)“…Abstract Background Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to…”
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Identification of a Novel L-rhamnose Uptake Transporter in the Filamentous Fungus Aspergillus niger
Published in PLoS genetics (01-12-2016)“…The study of plant biomass utilization by fungi is a research field of great interest due to its many implications in ecology, agriculture and biotechnology…”
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Towards understanding Pseudomonas aeruginosa burn wound infections by profiling gene expression
Published in Biotechnology letters (01-05-2008)“…Pseudomonas aeruginosa is a key opportunistic pathogen causing severe acute and chronic nosocomial infections in immunocompromised or catheterized patients. It…”
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Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections
Published in BMC medicine (04-05-2022)“…Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial…”
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13
Immunoglobulins drive terminal maturation of splenic dendritic cells
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2013)“…Nature and physiological status of antigen-presenting cells, such as dendritic cells DCs, are decisive for the immune reactions elicited. Multiple factors and…”
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DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems
Published in BMC systems biology (19-06-2018)“…Models of metabolism are often used in biotechnology and pharmaceutical research to identify drug targets or increase the direct production of valuable…”
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D-Lactic Acid Production from Sugarcane Bagasse by Genetically Engineered Saccharomyces cerevisiae
Published in Journal of fungi (Basel) (03-08-2022)“…Lactic acid (LA) is a promising bio-based chemical that has broad applications in food, nutraceutical, and bioplastic industries. However, production of the…”
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From correlation to causation: analysis of metabolomics data using systems biology approaches
Published in Metabolomics (2018)“…Introduction Metabolomics is a well-established tool in systems biology, especially in the top–down approach. Metabolomics experiments often results in…”
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Understanding the antimicrobial mechanism of TiO2-based nanocomposite films in a pathogenic bacterium
Published in Scientific reports (19-02-2014)“…Titania (TiO 2 )-based nanocomposites subjected to light excitation are remarkably effective in eliciting microbial death. However, the mechanism by which…”
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Identification of Aspergillus niger Aquaporins Involved in Hydrogen Peroxide Signaling
Published in Journal of fungi (Basel) (21-04-2023)“…is a robust microbial cell factory for organic acid production. However, the regulation of many industrially important pathways is still poorly understood. The…”
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Efficient Reconstruction of Predictive Consensus Metabolic Network Models
Published in PLoS computational biology (01-08-2016)“…Understanding cellular function requires accurate, comprehensive representations of metabolism. Genome-scale, constraint-based metabolic models (GSMs) provide…”
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The revisited genome of Pseudomonas putida KT2440 enlightens its value as a robust metabolic chassis
Published in Environmental microbiology (01-10-2016)“…Summary By the time the complete genome sequence of the soil bacterium Pseudomonas putida KT2440 was published in 2002 (Nelson et al., ) this bacterium was…”
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