Search Results - "Martins Santana, Jaime"
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1
International collaboration in Brazilian science: financing and impact
Published in Scientometrics (2020)“…The study of international collaborations can help in understanding the benefits of such relationships and aid in developing national financing policies. In…”
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The biotechnological potential of proteases from hematophagous arthropod vectors
Published in Frontiers in cellular and infection microbiology (26-10-2023)Get full text
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Ovicidal and Deleterious Effects of Cashew (Anacardium occidentale) Nut Shell Oil and Its Fractions on Musca domestica, Chrysomya megacephala, Anticarsia gemmatalis and Spodoptera frugiperda
Published in Chemistry & biodiversity (01-05-2019)“…In this work, we evaluated the ovicidal activity and the deleterious effects of cashew (Anacardium occidentale) nut shell oil and its fractions on the…”
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Oligopeptidase B, a missing enzyme in mammals and a potential drug target for trypanosomatid diseases
Published in Biochimie (01-12-2019)“…Oligopeptidases B (OPB) belong to the S9 prolyl oligopeptidase family and are expressed in prokaryotes, some eukaryotes and in some higher plants. OPB is not…”
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Identification of novel Zika virus NS3 protease inhibitors with different inhibition modes by integrative experimental and computational approaches
Published in Biochimie (01-09-2023)“…Zika virus (ZIKV) infection is associated with severe neurological disorders and congenital malformation. Despite efforts to eradicate the disease, there is…”
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Metacyclogenesis as the Starting Point of Chagas Disease
Published in International journal of molecular sciences (21-12-2023)“…Chagas disease is a neglected infectious disease caused by the protozoan , primarily transmitted by triatomine vectors, and it threatens approximately…”
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Enhanced IL-6 and IL-12B Gene Expression After SARS-CoV-2 Infection in Leprosy Patients May Increase the Risk of Neural Damage
Published in The American journal of tropical medicine and hygiene (01-06-2021)“…Experts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome on the progression of…”
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Effects of an anticarcinogenic Bowman-Birk protease inhibitor on purified 20S proteasome and MCF-7 breast cancer cells
Published in PloS one (27-01-2014)“…Proteasome inhibitors have been described as an important target for cancer therapy due to their potential to regulate the ubiquitin-proteasome system in the…”
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Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition
Published in BMC complementary and alternative medicine (08-11-2016)“…The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug…”
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Proteomic Mapping of Multifunctional Complexes Within Triatomine Saliva
Published in Frontiers in cellular and infection microbiology (02-09-2020)“…Triatomines are hematophagous insects that transmit , the etiological agent of Chagas disease. This neglected tropical disease represents a global health issue…”
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An Integrative Sialomic Analysis Reveals Molecules From Triatoma sordida (Hemiptera: Reduviidae)
Published in Frontiers in cellular and infection microbiology (03-01-2022)“…Triatomines have evolved salivary glands that produce versatile molecules with various biological functions, including those leading their interactions with…”
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Insights into the microRNA landscape of Rhodnius prolixus, a vector of Chagas disease
Published in Scientific reports (12-08-2023)“…The growing interest in microRNAs (miRNAs) over recent years has led to their characterization in numerous organisms. However, there is currently a lack of…”
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Larvicidal and pupicidal activities of eco-friendly phenolic lipid products from Anacardium occidentale nutshell against arbovirus vectors
Published in Environmental science and pollution research international (01-02-2019)“…Aedes aegypti and Culex quinquefasciatus are vectors of diseases that constitute public health problems. The discovery of products capable of inhibiting their…”
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Liposomes Composed by Membrane Lipid Extracts from Macrophage Cell Line as a Delivery of the Trypanocidal N,N’-Squaramide 17 towards Trypanosoma cruzi
Published in Materials (02-12-2020)“…Chagas is a neglected tropical disease caused by Trypanosoma cruzi, and affects about 25 million people worldwide. N, N’-Squaramide 17 (S) is a trypanocidal…”
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The Trypanosoma cruzi virulence factor oligopeptidase B (OPBTc) assembles into an active and stable dimer
Published in PloS one (19-01-2012)“…Oligopeptidase B, a processing enzyme of the prolyl oligopeptidase family, is considered as an important virulence factor in trypanosomiasis. Trypanosoma cruzi…”
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Triatomines: Trypanosomatids, Bacteria, and Viruses Potential Vectors?
Published in Frontiers in cellular and infection microbiology (16-11-2018)“…Triatominae bugs are the vectors of Chagas disease, a major concern to public health especially in Latin America, where vector-borne Chagas disease has…”
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Exploring the molecular complexity of Triatoma dimidiata sialome
Published in Journal of proteomics (01-03-2018)“…Triatoma dimidiata, a Chagas disease vector widely distributed along Central America, has great capability for domestic adaptation as the majority of specimens…”
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Trypanocidal activity of a new pterocarpan and other secondary metabolites of plants from Northeastern Brazil flora
Published in Bioorganic & medicinal chemistry (15-02-2008)“…This novel pterocarpan showed activity in vitro against epimastigote forms of Trypanosoma cruzi using the tetrazolium salt MTT as an alternative method. Two…”
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Detection of a homotetrameric structure and protein-protein interactions of Paracoccidioides brasiliensis formamidase lead to new functional insights
Published in FEMS yeast research (01-02-2010)“…Paracoccidioides brasiliensis causes paracoccidioidomycosis, a systemic mycosis in Latin America. Formamidases hydrolyze formamide, putatively plays a role in…”
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Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function
Published in FEMS yeast research (01-12-2007)“…Paracoccidioides brasiliensis is an important fungal pathogen. The disease it causes, paracoccidioidomycosis (PCM), ranges from localized pulmonary infection…”
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