Search Results - "Martins Gelfuso, Guilherme"

Wound Healing Effect of Essential Oil Extracted from Eugenia dysenterica DC (Myrtaceae) Leaves by Mazutti da Silva, Sandra Márcia, Rezende Costa, Claudio Rodrigues, Martins Gelfuso, Guilherme, Silva Guerra, Eliete Neves, de Medeiros Nóbrega, Yanna Karla, Gomes, Sueli Maria, Pic-Taylor, Aline, Fonseca-Bazzo, Yris Maria, Silveira, Damaris, Magalhães, Pérola de Oliveira

“…The use of natural oils in topical pharmaceutical preparations has usually presented safe agents for the improvement of human health. Based on research into…”
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A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery by Gratieri, Taís, Gelfuso, Guilherme Martins, Rocha, Eduardo Melani, Sarmento, Victor Hugo, de Freitas, Osvaldo, Lopez, Renata Fonseca Vianna

“…The aim of the present work was to obtain an ophthalmic delivery system with improved mechanical and mucoadhesive properties that could provide prolonged…”
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Improving stability of antioxidant compounds from Plinia cauliflora (jabuticaba) fruit peel extract by encapsulation in chitosan microparticles by Cabral, Bruna Reis Pimenta, de Oliveira, Paula Martins, Gelfuso, Guilherme Martins, Quintão, Tatyane de Souza Cardoso, Chaker, Juliano Alexandre, Karnikowski, Margô Gomes de Oliveira, Gris, Eliana Fortes

“…The present work aimed to microencapsulate the phenolic extract of jabuticaba peel and to evaluate the stabilization of antioxidant compounds provided by the…”
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Characterization of ibrutinib's effects on the morphology, proliferation, phenotype, viability, and anti-inflammatory potential of adipose-derived mesenchymal stromal cells by Silva-Carvalho, Amandda Évelin, Bispo, Elizabete Cristina Iseke, da Silva, Ingrid Gracielle Martins, Correa, José Raimundo, Carvalho, Juliana Lott, Gelfuso, Guilherme Martins, Saldanha-Araujo, Felipe

“…Ibrutinib (IB) is a tyrosine kinase inhibitor (TKI) that has immunomodulatory action and can be used as second-line therapy for steroid-refractory or…”
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Medicine manipulation: An alternative to mitigate therapeutic gaps in the Brazilian Unified Health System? by Okamoto, Gabriel Gonçalves, dos Santos, Kathiely Martins, Nogueira, Luma de Lira, Gelfuso, Guilherme Martins, Santana, Rafael Santos

“…Despite the various initiatives carried out in Brazil and in the world, the challenge of offering essential medicines in adequate presentations remains,…”
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Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel by Gratieri, Taís, Gelfuso, Guilherme Martins, de Freitas, Osvaldo, Rocha, Eduardo Melani, Lopez, Renata F.V.

“…FLU aqueous humor concentrations assessed by microdialysis in rabbits after the topical administration of the following: (i) poloxamer/chitosan in situ forming…”
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Liquid chromatography-mass spectrometry for simultaneous determination of spironolactone and canrenone in plasma samples by Ferreira-Nunes, Ricardo, Almeida, Edson Aliel Teixeira de, Cunha-Filho, Marcilio, Gratieri, Tais, Gelfuso, Guilherme Martins

“…In our study, we aimed to validate a method based on liquid chromatography-mass spectrometry (LC-MS) to quantify spironolactone (SPI) and its active metabolite…”
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Incorporation of Eugenia dysenterica extract in microemulsions preserves stability, antioxidant effect and provides enhanced cutaneous permeation by Ferreira-Nunes, Ricardo, Silva, Sandra Márcia Mazutti da, Souza, Paulo Eduardo Narcizo de, Magalhães, Pérola de Oliveira, Cunha-Filho, Marcílio, Gratieri, Taís, Gelfuso, Guilherme Martins

“…The aim of this paper was to develop stable, non-irritant topical formulations for the incorporation of aqueous extract from Eugenia dysenterica leaves, which…”
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Multi-level toxicity assessment of the antidepressant venlafaxine in embryos/larvae and adults of zebrafish (Danio rerio) by Oliveira, Ana Clara, Fascineli, Maria Luiza, Oliveira, Paula Martins de, Gelfuso, Guilherme Martins, Villacis, Rolando André Rios, Grisolia, Cesar Koppe

“…The toxic effects of venlafaxine (VLX) on aquatic organisms have already been verified and therefore are a proven matter of concern. Herein, we evaluated…”
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Microemulsions incorporating Brosimum gaudichaudii extracts as a topical treatment for vitiligo: In vitro stimulation of melanocyte migration and pigmentation by Quintão, Wanessa de Souza Cardoso, Alencar-Silva, Thuany, Borin, Maria de Fátima, Rezende, Kennia Rocha, Albernaz, Lorena C., Cunha-Filho, Marcilio, Gratieri, Tais, de Carvalho, Juliana Lott, Sá-Barreto, Livia C.L., Gelfuso, Guilherme Martins

“…The purpose of the study reported here was to develop and characterize microemulsions incorporating two ethanolic extracts of Brosimum gaudichaudii with…”
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Topical ophthalmic antimicrobials: unfulfilled demands and possibility of new investments in Brazil and in the United States by Kollross, Bianca, Gelfuso, Guilherme Martins, Cunha-Filho, Marcilio, Gratieri, Tais

“…In general, topical ophthalmic drug products, especially those used for treating infections, present low effectiveness because of various reasons, from…”
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Ibrutinib Modulates Proliferation, Migration, Mitochondrial Homeostasis, and Apoptosis in Melanoma Cells by Lins, Fernanda Vitelli, Bispo, Elizabete Cristina Iseke, Rodrigues, Naomí Souza, Silva, Maria Victória Souto, Carvalho, Juliana Lott, Gelfuso, Guilherme Martins, Saldanha-Araujo, Felipe

“…Ibrutinib, a tyrosine kinase inhibitor with a broad spectrum of action, has been successfully explored to treat hematological and solid cancers. Herein, we…”
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Skin Regenerative Potential of Cupuaçu Seed Extract ( Theobroma grandiflorum ), a Native Fruit from the Amazon: Development of a Topical Formulation Based on Chitosan-Coated Nanocapsules by Barbalho, Geisa Nascimento, Matos, Breno Noronha, da Silva Brito, Gabriel Ferreira, da Cunha Miranda, Thamires, Alencar-Silva, Thuany, Sodré, Fernando Fabriz, Gelfuso, Guilherme Martins, Cunha-Filho, Marcilio, Carvalho, Juliana Lott, da Silva, Joyce Kelly do Rosário, Gratieri, Taís

“…Scarless skin regeneration is a challenge in regenerative medicine. Herein, we explore the regenerative potential of a Cupuaçu seed extract ( ) to develop an…”
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Active Potential of Bacterial Cellulose-Based Wound Dressing: Analysis of Its Potential for Dermal Lesion Treatment by Hodel, Katharine Valéria Saraiva, Machado, Bruna Aparecida Souza, Sacramento, Giulia da Costa, Maciel, Carine Assunção de Oliveira, Oliveira-Junior, Gessualdo Seixas, Matos, Breno Noronha, Gelfuso, Guilherme Martins, Nunes, Silmar Baptista, Barbosa, Josiane Dantas Viana, Godoy, Ana Leonor Pardo Campos

“…The use of innate products for the fast and efficient promotion of healing process has been one of the biomedical sector’s main bets for lesion treatment…”
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Regulatory Requirements and Innovation: A Comparison of the Dermatologic Antifungal Drug Product Markets in Brazil and United States by Kollross, Bianca, Cunha-Filho, Marcilio, Gelfuso, Guilherme Martins, Gratieri, Tais

“…Development of novel dermatological topical products for the treatment of cutaneous fungal infections is a constant necessity, especially in developing…”
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Characterization and Determination of the Antibacterial Activity of Baccharis dracunculifolia Essential-Oil Nanoemulsions by Monteiro, Erika da Silva, da Silva, Franklyn Santos, Gomes, Karolina Oliveira, do Prado, Bruno Alcântara, Dos Santos, Rebeca Dias, Gomes da Camara, Claudio Augusto, de Moraes, Marcilio Martins, Silva, Izabel Cristina Rodrigues da, de Macêdo, Vinicius Teixeira, Gelfuso, Guilherme Martins, Sá Barreto, Lívia Cristina Lira de, Orsi, Daniela Castilho

“…The aim of this study was to evaluate the antibacterial activity of nanoemulsions of essential oil. The volatile compounds of the essential oil were identified…”
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Chitosan microparticles for sustaining the topical delivery of minoxidil sulphate by Gelfuso, Guilherme Martins, Gratieri, Taís, Simão, Patrícia Sper, de Freitas, Luís Alexandre Pedro, Lopez, Renata Fonseca Vianna

“…Given the hypothesis that microparticles can penetrate the skin barrier along the transfollicular route, this work aimed to obtain and characterise chitosan…”
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Bioequivalence of dermatological topical medicines:the Brazilian scenario and the challenges for health surveillance by Soares, Kelen Carine Costa, Moraes, Marcelo Vogler, Gelfuso, Guilherme Martins, Gratieri, Taís

“…The comparative evaluation required for the registration of generic topical medicines in Brazil is conducted by means of a pharmaceutical equivalence study,…”
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The effects of pH and ionic strength on topical delivery of a negatively charged porphyrin (TPPS4) by Gelfuso, Guilherme Martins, Figueiredo, Fábio Vasconcelos, Gratieri, Taís, Lopez, Renata Fonseca Vianna

“…Meso-tetra-[4-sulfonatophenyl]-porphyrin (TPPS(4)) is a charged porphyrin derivate used in photodynamic therapy (PDT) by parenteral administration. This study…”
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Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies by Cunha-Filho, Marcilio S. S., Joanitti, Graziella A., Bentes de Azevedo, Ricardo, Gratieri, Taís, Alves, Rubens da Costa, Jaculi, Ana Elise, Reis, Thaiene Avila, Gelfuso, Guilherme Martins

“…Considering the feasibility of the aluminum phthalocyanine chloride (AlPcCl) application in the topical photodynamic therapy of cutaneous tumors and the lack…”
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