Search Results - "Martins Chaves, Mı́riam"
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Increase of reactive oxygen (ROS) and nitrogen (RNS) species generated by phagocyting granulocytes related to age
Published in Mechanisms of ageing and development (20-10-2000)“…In this present paper the age-induced effect on reactive oxidizing species generated by oxygen (ROS) and nitrogen (RNS) was studied using human phagocyting…”
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Baccharis trimera (Carqueja) Improves Metabolic and Redox Status in an Experimental Model of Type 1 Diabetes
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Diabetes mellitus is a metabolic disorder that causes severe complications due to the increased oxidative stress induced by disease. Many plants are popularly…”
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Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen
Published in Mediators of Inflammation (01-01-2014)“…Background. Acetaminophen (APAP) is a commonly used analgesic and antipyretic. When administered in high doses, APAP is a clinical problem in the US and…”
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From hyperglycemia to AGE-RAGE interaction on the cell surface: a dangerous metabolic route for diabetic patients
Published in Expert opinion on therapeutic targets (01-07-2008)“…Diabetes mellitus constitutes a serious public health problem. Recent advances in therapies are unable to control its vascular complications. New medications…”
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Antioxidant properties of Baccharis trimera in the neutrophils of Fisher rats
Published in Journal of ethnopharmacology (16-06-2010)“…In vitro, the hydroethanolic extract of Baccharis trimera 5.0 μg/mL (Bt5) reduced the release of reactive oxygen species (RLU/30 min) in neutrophils, even…”
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Ascorbic acid, alpha-tocopherol, and beta-carotene reduce oxidative stress and proinflammatory cytokines in mononuclear cells of Alzheimer's disease patients
Published in Nutritional neuroscience (01-11-2012)“…Objectives The in vitro effect of a vitamin complex in generating and reducing oxidative species in peripheral blood mononuclear cells (PBMNC) and plasma of…”
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Baccharis trimera improves the antioxidant defense system and inhibits iNOS and NADPH oxidase expression in a rat model of inflammation
Published in Current pharmaceutical biotechnology (01-11-2013)“…Acetaminophen is a common analgesic and antipyretic compound which, when administered in high doses, has been associated with significant morbidity and…”
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Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats
Published in Journal of Clinical Biochemistry and Nutrition (01-05-2012)“…Annatto has been identified as carotenoids that have antioxidative effects. It is well known that one of the key elements in the development of diabetic…”
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Role PKA and p38 MAPK on ROS production in neutrophil age-related: Lack of IL-10 effect in older subjects
Published in Mechanisms of ageing and development (01-09-2009)“…There is a large increase in the number of elderly people in modern societies. This demographic phenomenon has been paralleled by an epidemic of chronic…”
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Antioxidant effect of Resveratrol: Change in MAPK cell signaling pathway during the aging process
Published in Archives of gerontology and geriatrics (01-01-2021)“…•Resveratrol is a polyphenol with potent antioxidant effect.•Elderly individuals have higher baseline oxidative stress.•Resveratrol has better antioxidant…”
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Role of inositol 1,4,5-triphosphate and p38 mitogen-activated protein kinase in reactive oxygen species generation by granulocytes in a cyclic AMP-dependent manner: an age-related phenomenon
Published in Gerontology (Basel) (01-01-2007)“…It is generally agreed that elderly subjects undergo progressive deterioration of their immune responsiveness, which leads to an increased susceptibility to…”
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Nrf2 cell signaling pathway is responsible for the antioxidant effect of resveratrol in aging
Published in Geriatrics & gerontology international (01-09-2024)“…Introduction One of the markers of aging is oxidative stress, a condition characterized by an increase in free radicals concomitant with a reduction in…”
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Aging: functional metabolic balance among cAMP, cGMP and reactive oxygen intermediate generation by human granulocytes
Published in Gerontology (Basel) (01-11-2005)“…The nature of the aging process has been the subject of considerable speculation. It has been reported that in the aging process several components of the…”
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Correlation between NADPH oxidase and protein kinase C in the ROS production by human granulocytes related to age
Published in Gerontology (Basel) (01-11-2002)“…Aging may be defined as gradual and progressive changes in an organism that increase the probability of death. Accumulating evidence now indicates that the sum…”
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Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats
Published in Free radical research (01-03-2012)“…Annatto (Bixa orellana L.) contains a mixture of orange-yellowish pigments due to the presence of various carotenoids that have antioxidant effect. The immune…”
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Host defenses in the aged: evaluation of the balance between oxidizing species generation and reducing power in phagocyting human granulocytes
Published in Mechanisms of ageing and development (01-08-1998)“…The respiratory burst reaction has been studied in human granulocytes from normal subjects divided in four age groups: (I) 20–29, (II) 30–39, (III) 40–49, and…”
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Effect of captopril and the bradykinin-PKC pathway on ROS production in type 1 diabetic rats
Published in Canadian journal of physiology and pharmacology (01-12-2011)“…The aim of this study was to investigate the possible effects of captopril as a promoter in modulating the oxidant-antioxidant balance in rats with type 1…”
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Oxidizing and reducing responses of granulocytes from type 2 diabetic patients
Published in Metabolism, clinical and experimental (01-10-2006)“…Oxidizing/reducing response by granulocytes and a potential correlation between reactive oxygen species generation and triglyceride, total cholesterol,…”
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Silencing of the Nrf2 pathway in aging promotes a decrease in the anti-inflammatory effect of resveratrol
Published in Archives of gerontology and geriatrics (01-02-2025)“…•Aging is related to oxidative stress and inflammation.•Resveratrol, through Nrf2, appears to act in the increase of IL-10.•The Nrf2 cell signaling pathway is…”
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Resveratrol: Change of SIRT 1 and AMPK signaling pattern during the aging process
Published in Experimental gerontology (01-04-2021)“…One of the causes for aging is free radical damage. Resveratrol (RSV), a polyphenolic compound has been shown to act as an antioxidant and anti-inflammatory…”
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