Search Results - "Martins, Teresa C"

Claspin: From replication stress and DNA damage responses to cancer therapy by Azenha, Diana, Lopes, Maria Celeste, Martins, Teresa C

“…Cancer is still one of the major causes of death worldwide. Radiation therapy and chemotherapy remain the main treatment modalities in cancer. These therapies…”
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In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp by Prazeres, Hugo, Couto, Joana P, Rodrigues, Fernando, Vinagre, João, Torres, Joana, Trovisco, Vitor, Martins, Teresa C, Sobrinho-Simões, Manuel, Soares, Paula

“…Multiple endocrine neoplasia type 2 and a subset of apparently sporadic medullary thyroid carcinoma (AS-MTC) are caused by germ line activating point mutations…”
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Claspin functions in cell homeostasis—A link to cancer? by Azenha, Diana, Lopes, Maria Celeste, Martins, Teresa C.

“…•Claspin is a pivotal cell cycle checkpoint protein.•Claspin has an important role in the maintenance of genomic integrity.•Regulation of Claspin’s levels…”
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CD38 plays a role in effective containment of mycobacteria within granulomata and polarization of Th1 immune responses against Mycobacterium avium by Viegas, Marta S., do Carmo, Anália, Silva, Teresa, Seco, Francisco, Serra, Vasco, Lacerda, Manuela, Martins, Teresa C.

“…CD38 is a multifunctional ectoenzyme that behaves either as an enzyme, a cell adhesion molecule or as a cell surface receptor involved in cell signalling. It…”
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Adult Attachment and Dyadic Adjustment: The Mediating Role of Shame by Martins, Teresa C., Canavarro, Maria Cristina, Moreira, Helena

“…Although it is widely recognized that adult attachment is associated with romantic relationship quality, the mechanisms involved remain poorly understood. This…”
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Adult attachment insecurity and dyadic adjustment: The mediating role of self-criticism by Martins, Teresa C., Canavarro, Maria Cristina, Moreira, Helena

“…Objectives Although it is well established that adult attachment is associated with relationship quality, the mechanisms involved in this association are still…”
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Implications of CLSPN Variants in Cellular Function and Susceptibility to Cancer by Azenha, Diana, Hernandez-Perez, Santiago, Martin, Yuse, Viegas, Marta S, Martins, Alexandra, Lopes, Maria C, Lam, Eric W-F, Freire, Raimundo, Martins, Teresa C

“…Claspin is a multifunctional protein that participates in physiological processes essential for cell homeostasis that are often defective in cancer, namely due…”
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In vitro transforming potential, intracellular signaling properties and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu and Arg886Trp by Prazeres, Hugo, Couto, Joana P, Rodrigues, Fernando, Vinagre, João, Torres, Joana, Trovisco, Vitor, Martins, Teresa C, Sobrinho-Simões, Manuel, Soares, Paula

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Complete genotyping of mucosal human papillomavirus using a restriction fragment length polymorphism analysis and an original typing algorithm by Nobre, Rui Jorge, de Almeida, Luís Pereira, Martins, Teresa C

“…Abstract Background Due to the differences in the oncogenic activity of human papillomaviruses (HPV), it is clinically important to accurately identify HPV…”
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Knocking out of CD38 accelerates development of a lupus-like disease in lpr mice by Viegas, Marta S, Silva, Teresa, Monteiro, Maria M, do Carmo, Anália, Martins, Teresa C

“…CD38 participates in lymphocyte ontogeny and function and may be involved in autoimmunity. Absence of CD38 accelerates development of non-obese diabetic (NOD)…”
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Characterization of common and rare human papillomaviruses in Portuguese women by the polymerase chain reaction, restriction fragment length polymorphism and sequencing by Nobre, Rui Jorge, Cruz, Eugénia, Real, Odete, de Almeida, Luís Pereira, Martins, Teresa C

“…The present study aimed to provide additional information on the prevalence of mucosal human papillomavirus (HPV) types in Portuguese women by using polymerase…”
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Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma by Prazeres, Hugo João, Rodrigues, Fernando, Soares, Paula, Naidenov, Plamen, Figueiredo, Paulo, Campos, Beatriz, Lacerda, Manuela, Martins, Teresa C.

“…Linkage studies have identified susceptibility loci for familial nonmedullary thyroid cancer (FNMTC), with and without cell oxyphilia, at chromosomal regions…”
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Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal by Prazeres, Hugo João, Rodrigues, Fernando, Figueiredo, Paulo, Naidenov, Plamen, Soares, Paula, Bugalho, Maria João, Lacerda, Manuela, Campos, Beatriz, Martins, Teresa C.

“…Summary Objective  Medullary thyroid carcinoma (MTC) occurs both sporadically and in the context of autosomal dominantly inherited multiple endocrine neoplasia…”
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Knocking out of CD38 accelerates development of a lupus-like disease in Ipr mice by VIEGAS, Marta S, SILVA, Teresa, MONTEIRO, Maria M, DO CARMO, Anália, MARTINS, Teresa C

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A Hybrid Density Functional-Classical Molecular Dynamics Simulation of a Water Molecule in Liquid Water by Tuñón, Iñaki, Martins-Costa, Marilia Teresa C., Millot, Claude, Ruiz-López, Manuel F.

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Complete genotyping of mucosal human papillomavims using a restriction fragment length polymorphism analysis and an original typing algorithm by NOBRE, Rui Jorge, DE ALMEIDA, Luis Pereira, MARTINS, Teresa C

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ORIGINAL ARTICLE: Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal by Prazeres, Hugo Joao, Rodrigues, Fernando, Figueiredo, Paulo, Naidenov, Plamen, Soares, Paula, Bugalho, Maria Joao, Lacerda, Manuela, Campos, Beatriz, Martins, Teresa C

“…Objective: Medullary thyroid carcinoma (MTC) occurs both sporadically and in the context of autosomal dominantly inherited multiple endocrine neoplasia type 2…”
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Mechanisms of Mycobacterium avium‐induced resistance against insulin‐dependent diabetes mellitus (IDDM) in non‐obese diabetic (NOD) mice: role of Fas and Th1 cells by MARTINS, T. C., ÁGUAS, A. P.

“…NOD mice spontaneously develop autoimmune diabetes. One of the manipulations that prevent diabetes in NOD mice is infection with mycobacteria or immunization…”
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Changes in B and T Lymphocytes Associated with Mycobacteria-induced Protection of NOD Mice from Diabetes by Martins, Teresa C., Águas, Artur P.

“…Most female NOD mice spontaneously develop insulin-dependent diabetes mellitus (IDDM) after the 4th month of age. We have recently reported that infection of…”
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NOD Mice are Resistant to Depletion of Thymic Cells Caused by Acute Stress or Infection by Martins, Teresa C., Aguas, Artur P.

“…NOD mice spontaneously develop autoimmune diabetes; disease onset in females of our colony of NOD mice usually takes place around the 4th month of age…”
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