Search Results - "Martins, Mariana Renovato"
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1
The remodel of the “central dogma”: a metabolomics interaction perspective
Published in Metabolomics (01-05-2021)“…Background In 1957, Francis Crick drew a linear diagram on a blackboard. This diagram is often called the “central dogma.” Subsequently, the relationships…”
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2
Minor red blood cell antigen phenotyping of athletes sampled in international competitions
Published in Drug testing and analysis (01-03-2023)“…Blood transfusion is performed by cheating athletes to rapidly increase oxygen delivery to exercise muscles and enhance their performance. This method is…”
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3
Effects of Lonomia obliqua Venom on Vascular Smooth Muscle Cells: Contribution of NADPH Oxidase-Derived Reactive Oxygen Species
Published in Toxins (07-11-2017)“…Envenomation caused by human contact with the caterpillar Lonomia is characterized by deleterious effects on coagulation and patency of blood vessels. The…”
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4
Obesity modifies bone marrow microenvironment and directs bone marrow mesenchymal cells to adipogenesis
Published in Obesity (Silver Spring, Md.) (01-12-2016)“…Objective To investigate the role of obesity on the bone marrow microenvironment and evaluate its possible impact on the adipogenic potential of mesenchymal…”
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5
Early overnutrition impairs insulin signaling in the heart of adult Swiss mice
Published in Journal of endocrinology (01-09-2008)“…Human overnutrition has caused a rise in the prevalence of obesity in recent years. In addition to the deleterious effects of obesity during childhood,…”
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6
Cellular and Molecular Mechanisms Associating Obesity to Bone Loss
Published in Cells (Basel, Switzerland) (01-02-2023)“…Obesity is an alarming disease that favors the upset of other illnesses and enhances mortality. It is spreading fast worldwide may affect more than 1 billion…”
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Extracellular vesicles as modulators of monocyte and macrophage function in tumors
Published in Anais da Academia Brasileira de Ciências (01-01-2024)“…The tumor microenvironment (TME) harbors several cell types, such as tumor cells, immune cells, and non-immune cells. These cells communicate through several…”
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8
Obese Adipose Tissue Secretion Induces Inflammation in Preadipocytes: Role of Toll-Like Receptor-4
Published in Nutrients (16-09-2020)“…In obesity, the dysfunctional adipose tissue (AT) releases increased levels of proinflammatory adipokines such as TNFα, IL-6, and IL-1β and free fatty acids…”
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9
Extracellular Vesicles From Stored Red Blood Cells Convey Heme and Induce Spic Expression on Human Monocytes
Published in Frontiers in immunology (18-05-2022)Get full text
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10
Effect of Lonomia obliqua Venom on Human Neutrophils
Published in Toxins (18-12-2021)“…The significant incidence of deforestation in South America culminates in the contact of humans with typical forests species. Among these species, one may…”
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11
Time Course of the Phenotype of Blood and Bone Marrow Monocytes and Macrophages in the Lung after Cigarette Smoke Exposure In Vivo
Published in International journal of molecular sciences (09-09-2017)“…Alveolar macrophages play a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Monocytes are recruited from blood during…”
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12
Unlocking the Secrets of Adipose Tissue: How an Obesity-Associated Secretome Promotes Osteoblast Dedifferentiation via TGF-β1 Signaling, Paving the Path to an Adipogenic Phenotype
Published in Cells (Basel, Switzerland) (25-08-2024)“…Obesity poses a significant global health challenge, given its association with the excessive accumulation of adipose tissue (AT) and various systemic…”
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13
Extracellular Vesicles Derived from MDA-MB-231 Cells Trigger Neutrophils to a Pro-Tumor Profile
Published in Cells (Basel, Switzerland) (09-06-2022)“…Immune system cells, including neutrophils, are recruited by the tumor microenvironment as a site of chronic inflammation and begin to favor tumor growth…”
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14
Increased leptin response and inhibition of apoptosis in thymocytes of young rats offspring from protein deprived dams during lactation
Published in PloS one (10-05-2013)“…We investigated the consequences of mild maternal malnutrition in rat dams, in terms of thymocyte responses and the putative role of leptin. The young progeny…”
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15
Obesity promotes alterations in iron recycling
Published in Nutrients (06-01-2015)“…Hepcidin is a key hormone that induces the degradation of ferroportin (FPN), a protein that exports iron from reticuloendothelial macrophages and enterocytes…”
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16
Long-term effects of overfeeding during lactation on insulin secretion — the role of GLUT-2
Published in The Journal of nutritional biochemistry (01-06-2009)“…Overnutrition during critical developmental periods is believed to be a risk factor for the emergence of metabolic disorders in adulthood. The present study…”
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17
Data in support of alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects in vascular smooth muscle cells
Published in Data in brief (01-03-2016)“…The data provides information in support of the research article Moraes et al., Atherosclerosis 243(2) (2015) 477–485 [1]. Here we provide data behind the…”
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18
Conditioned Medium Derived from Human Obese Adipose Tissue Induces Neutrophil Activation Via TLR-4
Published in Obesity (Silver Spring, Md.) (01-11-2023)“…Background: The adipose tissue buildup leads to inflammation, as evidenced by the increased number of immune system cell infiltrates, particularly neutrophils…”
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19
Profiling of the three circulating monocyte subpopulations in human obesity
Published in The Journal of immunology (1950) (15-04-2015)“…Three subpopulations of circulating monocytes have been described: CD14(2+)CD16(-) (classical monocytes [CM]), CD14(2+)CD16(+) (intermediate monocytes [IM]),…”
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Obese adipose tissue extracellular vesicles raise breast cancer cell malignancy
Published in Endocrine-related cancer (01-10-2020)“…Obesity is a chronic low-grade inflammatory condition that strongly impacts breast cancer. Aside from inflammatory mediators, obese adipose tissue (AT)…”
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