Search Results - "Martins, Grazieli Olinda"
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Impact of Degree of Ionization and PEGylation on the Stability of Nanoparticles of Chitosan Derivatives at Physiological Conditions
Published in Marine drugs (25-07-2022)“…Nowadays, the therapeutic efficiency of small interfering RNAs (siRNA) is still limited by the efficiency of gene therapy vectors capable of carrying them…”
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Amphipathic chitosans improve the physicochemical properties of siRNA-chitosan nanoparticles at physiological conditions
Published in Carbohydrate polymers (15-07-2019)“…[Display omitted] •Chitosan derivatives were synthesized and characterized.•Amphipathic character is tuned by degree of acetylation and tertiary amino…”
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Diethylaminoethyl- chitosan as an efficient carrier for siRNA delivery: Improving the condensation process and the nanoparticles properties
Published in International journal of biological macromolecules (01-11-2018)“…Chitosan has been indicated as a promising carrier for the preparation of small interfering RNA (siRNA) delivery systems due to its remarkable properties…”
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Journal Article