Search Results - "Martins, Berta M"
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Photoactivatable Mussel‐Based Underwater Adhesive Proteins by an Expanded Genetic Code
Published in Chembiochem : a European journal of chemical biology (19-09-2017)“…Marine mussels exhibit potent underwater adhesion abilities under hostile conditions by employing 3,4‐dihydroxyphenylalanine (DOPA)‐rich mussel adhesive…”
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Site‐Resolved Observation of Vibrational Energy Transfer Using a Genetically Encoded Ultrafast Heater
Published in Angewandte Chemie International Edition (25-02-2019)“…Allosteric information transfer in proteins has been linked to distinct vibrational energy transfer (VET) pathways in a number of theoretical studies…”
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3
Structural Basis for a Kolbe-Type Decarboxylation Catalyzed by a Glycyl Radical Enzyme
Published in Journal of the American Chemical Society (21-09-2011)“…4-Hydroxyphenylacetate decarboxylase is a [4Fe–4S] cluster containing glycyl radical enzyme proposed to use a glycyl/thiyl radical dyad to catalyze the last…”
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4
Determinants of substrate specificity and biochemical properties of the sn-glycerol-3-phosphate ATP binding cassette transporter (UgpB-AEC2) of Escherichia coli
Published in Molecular microbiology (01-11-2012)“…Summary Under phosphate starvation conditions, Escherichia coli can utilize sn‐glycerol‐3‐phosphate (G3P) and G3P diesters as phosphate source when transported…”
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Fermentative Cyclohexane Carboxylate Formation in Syntrophus aciditrophicus
Published in Journal of molecular microbiology and biotechnology (01-01-2016)“…Short-chain fatty acids such as acetic, propionic, butyric or lactic acids are typical primary fermentation products in the anaerobic feeding chain. Fifteen…”
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Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
Published in Biochemical journal (15-01-2010)“…The eukaryotic transcription elongation factor DSIF [DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole) sensitivity-inducing factor] is composed of two…”
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Crystal Structure of 4-Hydroxybutyryl-CoA Dehydratase: Radical Catalysis Involving a [4Fe-4S] Cluster and Flavin
Published in Proceedings of the National Academy of Sciences - PNAS (02-11-2004)“…Dehydratases catalyze the breakage of a carbon-oxygen bond leading to unsaturated products via the elimination of water. The 1.6-Å resolution crystal structure…”
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8
Basic Requirements for a Metal-Binding Site in a Protein: The Influence of Loop Shortening on the Cupredoxin Azurin
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2006)“…The main active-site loop of the copper-binding protein azurin (a cupredoxin) has been shortened from $C^{112}TPH^{117}PFM^{121}$ to…”
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9
Active Site Geometry and Substrate Recognition of the Molybdenum Hydroxylase Quinoline 2-Oxidoreductase
Published in Structure (London) (01-08-2004)“…The soil bacterium Pseudomonas putida 86 uses quinoline as a sole source of carbon and energy. Quinoline 2-oxidoreductase (Qor) catalyzes the first metabolic…”
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Double‐Cubane [8Fe9S] Clusters: A Novel Nitrogenase‐Related Cofactor in Biology
Published in Chembiochem : a European journal of chemical biology (15-06-2020)“…Three different types of electron‐transferring metallo‐ATPases are able to couple ATP hydrolysis to the reduction of low‐potential metal sites, thereby…”
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Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment
Published in Journal of molecular microbiology and biotechnology (01-01-2016)“…Hydrocarbons are abundant in anoxic environments and pose biochemical challenges to their anaerobic degradation by microorganisms. Within the framework of the…”
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Catalytic Mechanism of the Glycyl Radical Enzyme 4‑Hydroxyphenylacetate Decarboxylase from Continuum Electrostatic and QC/MM Calculations
Published in Journal of the American Chemical Society (02-10-2013)“…Using continuum electrostatics and QC/MM calculations, we investigate the catalytic cycle of the glycyl radical enzyme 4-hydroxyphenylacetate decarboxylase, an…”
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13
HTHP: A Novel Class of Hexameric, Tyrosine-coordinated Heme Proteins
Published in Journal of molecular biology (11-05-2007)“…We have cloned, expressed, isolated and characterized a hexameric tyrosine-coordinated heme protein (HTHP) from the marine bacterium Silicibacter pomeroyi…”
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Structure and Function of Benzylsuccinate Synthase and Related Fumarate-Adding Glycyl Radical Enzymes
Published in Journal of molecular microbiology and biotechnology (01-01-2016)“…The pathway of anaerobic toluene degradation is initiated by a remarkable radical-type enantiospecific addition of the chemically inert methyl group to the…”
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15
X-Ray Crystallography of Carbon Monoxide Dehydrogenases
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Carbon monoxide dehydrogenases (CODHs) are central players in the biogeochemical carbon monoxide (CO) cycle and have been extensively studied from the…”
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Carbon Monoxide Dehydrogenases
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Carbon monoxide dehydrogenases (CODHs) catalyze the reversible oxidation of CO with water to CO , two electrons, and two protons. Two classes of CODHs exist,…”
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Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL
Published in Angewandte Chemie International Edition (05-06-2023)“…Lanthipeptides are ribosomally‐synthesized natural products from bacteria featuring stable thioether‐crosslinks and various bioactivities. Herein, we report on…”
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Zero-field splittings in metHb and metMb with aquo and fluoro ligands: a FD-FT THz-EPR study
Published in Molecular physics (01-10-2013)“…A combined X-band and frequency-domain Fourier-transform THz electron paramagnetic resonance (FD-FT THz-EPR) approach has been employed to determine heme…”
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Substrate-induced radical formation in 4-hydroxybutyryl coenzyme A dehydratase from Clostridium aminobutyricum
Published in Applied and Environmental Microbiology (01-02-2015)“…4-Hydroxybutyryl-coenzyme A (CoA) dehydratase (4HBD) from Clostridium aminobutyricum catalyzes the reversible dehydration of 4-hydroxybutyryl-CoA to…”
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The ferredoxin-like domain of the activating enzyme is required for generating a lasting glycyl radical in 4-hydroxyphenylacetate decarboxylase
Published in Journal of biological inorganic chemistry (01-12-2014)“…4-Hydroxyphenylacetate decarboxylase-activating enzyme (4Hpad-AE) uses S -adenosylmethionine (SAM or AdoMet) and a [4Fe-4S] 2+/+ cluster (RS cluster) to…”
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