Search Results - "Martini, Veronica"

The chemokine landscape: one system multiple shades by Cecchinato, Valentina, Martini, Veronica, Pirani, Edisa, Ghovehoud, Elaheh, Uguccioni, Mariagrazia

“…Leukocyte trafficking is mainly governed by chemokines, chemotactic cytokines, which can be concomitantly produced in tissues during homeostatic conditions or…”
Get full text

T and B Cell Immune Responses to Influenza Viruses in Pigs by Holzer, Barbara, Martini, Veronica, Edmans, Matthew, Tchilian, Elma

“…Influenza viruses are an ongoing threat to humans and are endemic in pigs, causing considerable economic losses to farmers. Pigs are also a source of new…”
Get full text

Distribution of Droplets and Immune Responses After Aerosol and Intra-Nasal Delivery of Influenza Virus to the Respiratory Tract of Pigs by Martini, Veronica, Hinchcliffe, Michael, Blackshaw, Elaine, Joyce, Mary, McNee, Adam, Beverley, Peter, Townsend, Alain, MacLoughlin, Ronan, Tchilian, Elma

“…Recent evidence indicates that local immune responses and tissue resident memory T cells (T ) are critical for protection against respiratory infections but…”
Get full text

Inhibition of the Histone Methyltransferase EZH2 Enhances Protumor Monocyte Recruitment in Human Mesothelioma Spheroids by Mola, Silvia, Pinton, Giulia, Erreni, Marco, Corazzari, Marco, De Andrea, Marco, Grolla, Ambra A, Martini, Veronica, Moro, Laura, Porta, Chiara

“…Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a long latency period and dismal prognosis. Recently, tazemetostat (EPZ-6438), an…”
Get full text

Untargeted lipidomics reveal association of elevated plasma C18 ceramide levels with reduced survival in metastatic castration-resistant prostate cancer patients by Cattrini, Carlo, Manfredi, Marcello, Barboro, Paola, Ghirimoldi, Marco, Mennitto, Alessia, Martini, Veronica, Battioni, Alessio, Le Van, Marco, Gobbato, Simone, Branni, Carmen, Ayed, Rahma Ben, Pinato, David James, Catalano, Fabio, Zanardi, Elisa, Boccardo, Francesco, Gennari, Alessandra

“…Emerging evidence highlights the potential prognostic relevance of circulating lipids in metastatic castration-resistant prostate cancer (mCRPC), with a…”
Get full text

Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia by Patrussi, Laura, Capitani, Nagaja, Martini, Veronica, Pizzi, Marco, Trimarco, Valentina, Frezzato, Federica, Marino, Filippo, Semenzato, Gianpietro, Trentin, Livio, Baldari, Cosima T

“…Lymphocyte trafficking is orchestrated by chemokine and sphingosine 1-phosphate (S1P) receptors that enable homing and egress from secondary lymphoid organs…”
Get full text

Simultaneous Infection With Porcine Reproductive and Respiratory Syndrome and Influenza Viruses Abrogates Clinical Protection Induced by Live Attenuated Porcine Reproductive and Respiratory Syndrome Vaccination by Chrun, Tiphany, Maze, Emmanuel A, Vatzia, Eleni, Martini, Veronica, Paudyal, Basudev, Edmans, Matthew D, McNee, Adam, Manjegowda, Tanuja, Salguero, Francisco J, Wanasen, Nanchaya, Koonpaew, Surapong, Graham, Simon P, Tchilian, Elma

“…The porcine respiratory disease complex (PRDC) is responsible for significant economic losses in the pig industry worldwide. Porcine reproductive and…”
Get full text

Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model by Severin, Filippo, Urbani, Andrea, Varanita, Tatiana, Bachmann, Magdalena, Azzolini, Michele, Martini, Veronica, Pizzi, Marco, Tos, Angelo Paolo Dei, Frezzato, Federica, Mattarei, Andrea, Ghia, Paolo, Bertilaccio, Maria Teresa Sabrina, Gulbins, Erich, Paradisi, Cristina, Zoratti, Mario, Semenzato, Gianpietro Carlo, Leanza, Luigi, Trentin, Livio, Szabò, Ildiko

“…Ion channels are emerging as promising oncological targets. The potassium channels Kv1.3 and IKCa are highly expressed in the plasma membrane and mitochondria…”
Get full text

Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs by Edmans, Matthew, McNee, Adam, Porter, Emily, Vatzia, Eleni, Paudyal, Basu, Martini, Veronica, Gubbins, Simon, Francis, Ore, Harley, Ross, Thomas, Amy, Burt, Rachel, Morgan, Sophie, Fuller, Anna, Sewell, Andrew, Charleston, Bryan, Bailey, Mick, Tchilian, Elma

“…We have used the pig, a large natural host animal for influenza with many physiological similarities to humans, to characterize αβ, γδ T cell and antibody (Ab)…”
Get full text

Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Bonnet-Di Placido, Marie, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies…”
Get full text

Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model by Schmidt, Anna, Paudyal, Basudev, Villanueva-Hernández, Sonia, Mcnee, Adam, Vatzia, Eleni, Carr, Brigid Veronica, Schmidt, Selma, Mccarron, Amy, Martini, Veronica, Schroedel, Silke, Thirion, Christian, Waters, Ryan, Salguero, Francisco J, Gerner, Wilhelm, Tenbusch, Matthias, Tchilian, Elma

“…T cell responses directed against highly conserved viral proteins contribute to the clearance of the influenza virus and confer broadly cross-reactive and…”
Get full text

Insulin/IGF Axis in Breast Cancer: Clinical Evidence and Translational Insights by Biello, Federica, Platini, Francesca, D'Avanzo, Francesca, Cattrini, Carlo, Mennitto, Alessia, Genestroni, Silvia, Martini, Veronica, Marzullo, Paolo, Aimaretti, Gianluca, Gennari, Alessandra

“…Breast cancer (BC) is the most common neoplasm in women. Many clinical and preclinical studies investigated the possible relationship between host metabolism…”
Get full text

Simultaneous co-infection with swine influenza A and porcine reproductive and respiratory syndrome viruses potentiates adaptive immune responses by Chrun, Tiphany, Maze, Emmanuel A, Roper, Kelly J, Vatzia, Eleni, Paudyal, Basudev, McNee, Adam, Martini, Veronica, Manjegowda, Tanuja, Freimanis, Graham, Silesian, Adrian, Polo, Noemi, Clark, Becky, Besell, Emily, Booth, Georges, Carr, Brigid Veronica, Edmans, Matthew, Nunez, Alejandro, Koonpaew, Surapong, Wanasen, Nanchaya, Graham, Simon P, Tchilian, Elma

“…Porcine respiratory disease is multifactorial and most commonly involves pathogen co-infections. Major contributors include swine influenza A (swIAV) and…”
Get full text

Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival by Trimarco, Valentina, Ave, Elisa, Facco, Monica, Chiodin, Giorgia, Frezzato, Federica, Martini, Veronica, Gattazzo, Cristina, Lessi, Federica, Giorgi, Carlo Alberto, Visentin, Andrea, Castelli, Monica, Severin, Filippo, Zambello, Renato, Piazza, Francesco, Semenzato, Gianpietro, Trentin, Livio

“…Leukemic cells from Chronic Lymphocytic Leukemia (CLL) patients interact with stromal cells of the surrounding microenvironment. Mesenchymal Stromal Cells…”
Get full text

Immunogenicity and Protective Efficacy of Seasonal Human Live Attenuated Cold-Adapted Influenza Virus Vaccine in Pigs by Holzer, Barbara, Morgan, Sophie B, Martini, Veronica, Sharma, Rajni, Clark, Becky, Chiu, Christopher, Salguero, Francisco J, Tchilian, Elma

“…Influenza A virus infection is a global health threat to livestock and humans, causing substantial mortality and morbidity. As both pigs and humans are readily…”
Get full text

Correction: Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Placido, Marie Bonnet-Di, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…[This corrects the article DOI: 10.1371/journal.ppat.1009330.]…”
Get full text

Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins by Frezzato, Federica, Accordi, Benedetta, Trimarco, Valentina, Gattazzo, Cristina, Martini, Veronica, Milani, Gloria, Bresolin, Silvia, Severin, Filippo, Visentin, Andrea, Basso, Giuseppe, Semenzato, Gianpietro, Trentin, Livio

“…Identification of molecules involved in apoptosis control (HSP70, Smac/DIABLO, PARP and Caspase‐6), to consider in the design of innovative therapies for CLL…”
Get full text

Respiratory and Intramuscular Immunization With ChAdOx2-NPM1-NA Induces Distinct Immune Responses in H1N1pdm09 Pre-Exposed Pigs by Vatzia, Eleni, Allen, Elizabeth R, Manjegowda, Tanuja, Morris, Susan, McNee, Adam, Martini, Veronica, Kaliath, Reshma, Ulaszewska, Marta, Boyd, Amy, Paudyal, Basudev, Carr, Veronica B, Chrun, Tiphany, Maze, Emmanuel, MacLoughlin, Ronan, van Diemen, Pauline M, Everett, Helen E, Lambe, Teresa, Gilbert, Sarah C, Tchilian, Elma

“…There is a critical need to develop superior influenza vaccines that provide broader protection. Influenza vaccines are traditionally tested in naive animals,…”
Get full text

Patients with ankylosing spondylitis present a distinct CD8 T cell subset with osteogenic and cytotoxic potential by Martini, Veronica, Silvestri, Ylenia, Ciurea, Adrian, Möller, Burkhard, Danelon, Gabriela, Flamigni, Flavio, Jarrossay, David, Kwee, Ivo, Foglierini, Mathilde, Rinaldi, Andrea, Cecchinato, Valentina, Uguccioni, Mariagrazia

“…ObjectivesAnkylosing spondylitis (AS) is a chronic inflammatory rheumatic disease affecting mainly the axial skeleton. Peripheral involvement (arthritis,…”
Get full text

Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia by Gattazzo, Cristina, Martini, Veronica, Frezzato, Federica, Trimarco, Valentina, Tibaldi, Elena, Castelli, Monica, Facco, Monica, Zonta, Francesca, Brunati, Anna Maria, Zambello, Renato, Semenzato, Gianpietro, Trentin, Livio

“…Cortactin, an actin binding protein and Lyn substrate, is up-regulated in several cancers and its level is associated with increased cell migration, metastasis…”
Get full text