Search Results - "Martinho, Nuno"

Cisplatin-Membrane Interactions and Their Influence on Platinum Complexes Activity and Toxicity by Martinho, Nuno, Santos, Tânia C B, Florindo, Helena F, Silva, Liana C

“…Cisplatin and other platinum(II) analogs are widely used in clinical practice as anti-cancer drugs for a wide range of tumors. The primary mechanism by which…”
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Evaluation of Encapsulation Potential of Selected Star-Hyperbranched Polyglycidol Architectures: Predictive Molecular Dynamics Simulations and Experimental Validation by Gosecki, Mateusz, Urbaniak, Malgorzata, Martinho, Nuno, Gosecka, Monika, Zloh, Mire

“…Polymers, including non-linear copolymers, have great potential in the development of drug delivery systems with many advantages, but the design requires…”
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Molecular Modeling to Study Dendrimers for Biomedical Applications by Martinho, Nuno, Florindo, Helena, Silva, Liana, Brocchini, Steve, Zloh, Mire, Barata, Teresa

“…Molecular modeling techniques provide a powerful tool to study the properties of molecules and their interactions at the molecular level. The use of…”
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Using Machine Learning and Molecular Docking to Leverage Urease Inhibition Data for Virtual Screening by Aniceto, Natália, Albuquerque, Tânia S, Bonifácio, Vasco D B, Guedes, Rita C, Martinho, Nuno

“…Urease is a metalloenzyme that catalyzes the hydrolysis of urea, and its modulation has an important role in both the agricultural and medical industry. Even…”
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UrbanWater: Integrating EPANET 2 in a PostgreSQL/PostGIS-Based Geospatial Database Management System by Martinho, Nuno, Almeida, José-Paulo de, Simões, Nuno E., Sá-Marques, Alfeu

“…Incorporating data stored in a geographical information system (GIS) within the development of hydraulic simulation models is crucial for operating, updating,…”
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Drug carriers for oral delivery of peptides and proteins: accomplishments and future perspectives by Reis, Catarina Pinto, Silva, Catarina, Martinho, Nuno, Rosado, Catarina

“…Effective formulation for peptide and protein delivery through the oral route has always been the critical effort with the advent of biotechnology. Stability,…”
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Assessing the applicability of OpenStreetMap data to assist the validation of land use/land cover maps by Fonte, Cidália C., Martinho, Nuno

“…The validation of land use/land cover (LULC) maps is usually performed using a reference database consisting of a sample of points or regions to which the…”
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Exploring the Chemical Space of Urease Inhibitors to Extract Meaningful Trends and Drivers of Activity by Aniceto, Natália, Bonifácio, Vasco D. B., Guedes, Rita C., Martinho, Nuno

“…Blocking the catalytic activity of urease has been shown to have a key role in different diseases as well as in different agricultural applications. A vast…”
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Prática simulada: uma estratégia inovadora no presente e protagonista no futuro by António Borges, Nuno Martinho, Isabel Rabiais, Silvia Caldeira

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Experimental and numerical evaluation of a new visor concept with aerodynamic sealing to protect medical professionals from contaminated droplets and aerosols by Rosa, Nuno, Jordão, Mário, Costa, José, Gaspar, Adélio, Martinho, Nuno, Gameiro Lopes, António, Panão, Miguel, Gameiro da Silva, Manuel

“…The fast spreading of the SARS‐CoV‐2 virus led to a significant increase in the demand for personal protective equipment (PPE). Healthcare professionals,…”
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Effect of Cisplatin and Its Cationic Analogues in the Phase Behavior and Permeability of Model Lipid Bilayers by Martinho, Nuno, Marquês, Joaquim M. T., Todoriko, Iryna, Prieto, Manuel, de Almeida, Rodrigo F.M., Silva, Liana C.

“…Increasing evidence suggests a critical role of lipids in both the mechanisms of toxicity and resistance of cells to platinum­(II) complexes. In particular,…”
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Practical computational toolkits for dendrimers and dendrons structure design by Martinho, Nuno, Silva, Liana C., Florindo, Helena F., Brocchini, Steve, Barata, Teresa, Zloh, Mire

“…Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of…”
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Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment by Reis, Catarina Pinto, Martinho, Nuno, Rosado, Catarina, Fernandes, Ana S., Roberto, Amílcar

“…Abstract Objective: The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide) (PLGA) nanoparticles containing azelaic acid for…”
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Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles by Reis, Catarina Pinto, Gomes, Ana, Rijo, Patrícia, Candeias, Sara, Pinto, Pedro, Baptista, Marina, Martinho, Nuno, Ascensão, Lia

“…Azelaic acid (AzA) is used in the treatment of acne. However, side effects and low compliance have been associated with several topical treatments with AzA…”
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Synthesis and characterization of S-nitrosoglutathione-oligosaccharide-chitosan as a nitric oxide donor by Shah, Shefaat Ullah, Martinho, Nuno, Socha, Marie, Pinto Reis, Catarina, Gibaud, Stéphane

“…The aim of this work is to synthesize a novel stable and biodegradable nitric oxide (NO) donor polymer based on a chitosan backbone. This polymer needed to be…”
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Rational design of novel, fluorescent, tagged glutamic acid dendrimers with different terminal groups and in silico analysis of their properties by Martinho, Nuno, Silva, Liana C, Florindo, Helena F, Brocchini, Steve, Zloh, Mire, Barata, Teresa S

“…Dendrimers are hyperbranched polymers with a multifunctional architecture that can be tailored for the use in various biomedical applications. Peptide…”
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Fluorescent-Based Dendrimers as Potential Drug Delivery Carriers of Cisplatin: From Design and Synthesis to Platinum-Membrane Interactions by Martinho, Nuno Filipe Rodrigues

“…Dendrimers are a class of polymers with high potential as drug delivery systems due to their unique scaffold and properties. Despite their early potential,…”
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Da Enfermagem à Enfermagem Especializada : No Exercício da Competência Rumo à Excelência by Fernandes, Nuno Martinho Rodrigues

“…Este trabalho constitui um relatório de estágio, que tem como finalidade cumprir formalmente o módulo reflexivo dos contextos de estágio em âmbito de urgência…”
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Contributo Para a Análise do Toleranciamento em Solidworks by Martinho, Nuno Miguel Ribeiro

“…A presente dissertação tem como objetivo analisar e compreender o funcionamento dos recursos de toleranciamento dimensional do software SolidWorks,…”
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An off-line map-matching algorithm for incomplete map databases by Pereira, Francisco Câmara, Costa, Hugo, Pereira, Nuno Martinho

“…The task of map-matching consists of finding a correspondence between a geographical point or sequence of points (e.g. obtained from GPS) and a given map. Due…”
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