Search Results - "Martinez Saguer, Inmaculada"

Development of the Angioedema Control Test—A patient‐reported outcome measure that assesses disease control in patients with recurrent angioedema by Weller, Karsten, Donoso, Tamara, Magerl, Markus, Aygören‐Pürsün, Emel, Staubach, Petra, Martinez‐Saguer, Inmaculada, Hawro, Tomasz, Altrichter, Sabine, Krause, Karoline, Siebenhaar, Frank, Metz, Martin, Zuberbier, Torsten, Freier, Denise, Maurer, Marcus

“…Background Recurrent angioedema (AE) is an important clinical problem in the context of chronic urticaria (mast cell mediator–induced), ACE‐inhibitor intake…”
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Real World treatment patterns of hereditary angioedema with lanadelumab in Germany: A prescription data analysis by Martinez‐Saguer, Inmaculada, Knop, Jana, Flemming, Amadeus, Thomann, Michael, Maurer, Marcus

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Long‐term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study by Banerji, Aleena, Bernstein, Jonathan A., Johnston, Douglas T., Lumry, William R., Magerl, Markus, Maurer, Marcus, Martinez‐Saguer, Inmaculada, Zanichelli, Andrea, Hao, James, Inhaber, Neil, Yu, Ming, Riedl, Marc A., Hébert, J., Ritchie, B., Sussman, G., Yang, W.H., Aygören‐Pürsün, E., Magerl, M., Martinez‐Saguer, I., Staubach, P., Cicardi, M., Shennak, M., Zaragoza‐Urdaz, R.H., Kiani‐Alikhan, S., Anderson, J., Banerji, A., Baptist, A.P., Bernstein, J.A., Busse, P.J., Craig, T., Davis‐Lorton, M., Gierer, S., Gower, R.G., Harris, D., Jacobs, J., Johnston, D.T., Li, H.H., Lockey, R.F., Lugar, P., Lumry, W.R., Manning, M.E., McNeil, D.L., Melamed, I., Otto, W.R., Rehman, S.M., Riedl, M.A., Schwartz, L.B., Shapiro, R., Sher, E., Smith, A.M., Soteres, D., Tachdjian, R., Wedner, H.J., Weinstein, M.E., Zafra, H.

“…Background The aim was to evaluate long‐term effectiveness and safety of lanadelumab in patients ≥12 y old with hereditary angioedema (HAE) 1/2 (NCT02741596)…”
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International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency by Caballero, Teresa, MD, PhD, Farkas, Henriette, MD, PhD, DSc, Bouillet, Laurence, MD, PhD, Bowen, Tom, MD, Gompel, Anne, MD, PhD, Fagerberg, Christina, MD, Bjökander, Janne, MD, Bork, Konrad, MD, Bygum, Anette, MD, Cicardi, Marco, MD, de Carolis, Caterina, MD, Frank, Michael, MD, Gooi, Jimmy H.C., MD, Longhurst, Hilary, MD, Martínez-Saguer, Inmaculada, MD, Nielsen, Erik Waage, MD, Obtulowitz, Krystina, MD, Perricone, Roberto, MD, Prior, Nieves, MD

“…Background There are a limited number of publications on the management of gynecologic/obstetric events in female patients with hereditary angioedema caused by…”
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A randomized trial of human C1 inhibitor prophylaxis in children with hereditary angioedema by Aygören‐Pürsün, Emel, Soteres, Daniel F., Nieto‐Martinez, Sandra A., Christensen, Jim, Jacobson, Kraig W., Moldovan, Dumitru, Van Leerberghe, Arthur, Tang, Yongqiang, Lu, Peng, Vardi, Moshe, Schranz, Jennifer, Martinez‐Saguer, Inmaculada

“…Background Patients with hereditary angioedema with C1 inhibitor deficiency or dysfunction have burdensome recurrent angioedema attacks. The safety, efficacy,…”
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Hereditary angioedema in children and adolescents – A consensus update on therapeutic strategies for German‐speaking countries by Wahn, Volker, Aberer, Werner, Aygören‐Pürsün, Emel, Bork, Konrad, Eberl, Wolfgang, Faßhauer, Maria, Krüger, Renate, Magerl, Markus, Martinez‐Saguer, Inmaculada, Späth, Peter, Staubach‐Renz, Petra, Weber‐Chrysochoou, Christina, Atanaskovic‐Markovic, Marina

“…Background/Methods At a consensus meeting in August 2018, pediatricians and dermatologists from German‐speaking countries discussed the therapeutic strategy…”
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Successful management of hereditary angioedema during pregnancy in a patient with heterozygous MTHFR mutation by Martinez Saguer, Inmaculada, MD, Escuriola Ettingshausen, Carmen, MD

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Population pharmacokinetics of subcutaneous C1‐inhibitor for prevention of attacks in patients with hereditary angioedema by Pawaskar, Dipti, Tortorici, Michael A., Zuraw, Bruce, Craig, Timothy, Cicardi, Marco, Longhurst, Hilary, Li, H. Henry, Lumry, William R., Martinez‐Saguer, Inmaculada, Jacobs, Joshua, Bernstein, Jonathan A., Riedl, Marc A., Katelaris, Constance H., Keith, Paul K., Feussner, Annette, Sidhu, Jagdev

“…Summary Background Long‐term prophylaxis with subcutaneous (SC) administration of a highly concentrated plasma‐derived C1‐esterase inhibitor (C1‐INH)…”
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Epidemiology and treatment of children with hereditary angioedema in Germany: A retrospective database study by Prenzel, Freerk, Abraham, Susanne, Hirche, Christoph, Müller, Gerrit, Kaiser, Stephan, Serdani‐Neuhaus, Leonarda, Zingel, Rebecca, Martinez‐Saguer, Inmaculada

“…Background Hereditary angioedema (HAE) is a potentially life‐threatening inherited disease that causes recurrent, serious, and debilitating episodes of…”
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Current challenges and future opportunities in patient‐focused management of hereditary angioedema: A narrative review by Grumach, Anete S., Gadir, Noga, Kessel, Aharon, Yegin, Ashley, Martinez‐Saguer, Inmaculada, Bernstein, Jonathan A.

“…Patients with hereditary angioedema (HAE) experience a high burden of disease due to unpredictable, painful, disfiguring, and potentially life‐threatening HAE…”
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Behandlung des hereditären Angioödems mit Lanadelumab in der deutschen Versorgungsrealität: Eine Analyse von Verordnungsdaten by Martinez‐Saguer, Inmaculada, Knop, Jana, Flemming, Amadeus, Thomann, Michael, Maurer, Marcus

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Erythema Marginatum as an Early Symptom of Hereditary Angioedema: Case Report of 2 Newborns by Martinez-Saguer, Inmaculada, Farkas, Henriette

“…Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare genetic disease that causes recurrent swelling attacks that may affect various body…”
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The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update by Maurer, Marcus, Magerl, Markus, Betschel, Stephen, Aberer, Werner, Ansotegui, Ignacio J., Aygören‐Pürsün, Emel, Banerji, Aleena, Bara, Noémi‐Anna, Boccon‐Gibod, Isabelle, Bork, Konrad, Bouillet, Laurence, Boysen, Henrik Balle, Brodszki, Nicholas, Busse, Paula J., Bygum, Anette, Caballero, Teresa, Cancian, Mauro, Castaldo, Anthony, Cohn, Danny M., Csuka, Dorottya, Farkas, Henriette, Gompels, Mark, Gower, Richard, Grumach, Anete S., Guidos‐Fogelbach, Guillermo, Hide, Michihiro, Kang, Hye‐Ryun, Kaplan, Allen Phillip, Katelaris, Constance, Kiani‐Alikhan, Sorena, Lei, Wei‐Te, Lockey, Richard, Longhurst, Hilary, Lumry, William R., MacGinnitie, Andrew, Malbran, Alejandro, Martinez Saguer, Inmaculada, Matta, Juan José, Nast, Alexander, Nguyen, Dinh, Nieto‐Martinez, Sandra A., Pawankar, Ruby, Peter, Jonathan, Porebski, Grzegorz, Prior, Nieves, Reshef, Avner, Riedl, Marc, Ritchie, Bruce, Rafique Sheikh, Farrukh, Smith, William B., Spaeth, Peter J., Stobiecki, Marcin, Toubi, Elias, Varga, Lilian Agnes, Weller, Karsten, Zanichelli, Andrea, Zhi, Yuxiang, Zuraw, Bruce, Craig, Timothy

“…Hereditary angioedema (HAE) is a rare and disabling disease for which early diagnosis and effective therapy are critical. This revision and update of the…”
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Short-term prophylactic use of C1-inhibitor concentrate in hereditary angioedema by Magerl, Markus, MD, Frank, Michael, MD, Lumry, William, MD, Bernstein, Jonathan, MD, Busse, Paula, MD, Craig, Timothy, DO, Martinez-Saguer, Inmaculada, MD, Riedl, Marc A., MD, Shapiro, Ralph, MD, Edelman, Jonathan, MD, Williams-Herman, Debora, MD, Wood, Daniel N., PhD, Feuersenger, Henrike, PhD, Rojavin, Mikhail, PhD

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Efficacy and Safety of an Intravenous C1-Inhibitor Concentrate for Long-Term Prophylaxis in Hereditary angioedema by Craig, Timothy, Shapiro, Ralph, Vegh, Arthur, Baker, James W., Bernstein, Jonathan A., Busse, Paula, Magerl, Markus, Martinez-Saguer, Inmaculada, Riedl, Marc A., Lumry, William, Williams-Herman, Debora, Edelman, Jonathan, Feuersenger, Henrike, Machnig, Thomas, Rojavin, Mikhail

“…Background The plasma-derived, pasteurized, nanofiltered C1-inhibitor concentrate (pnfC1-INH) is approved in the United States as an intravenous (IV) on-demand…”
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Does Early Clinical Manifestation of Hereditary Angioedema (HAE) Influence the Clinical Course of the Disease? by Martinez-Saguer, Inmaculada, MD, Graff, Jochen, Rusicke, Eva, MD, Aygören-Pürsün, Emel, Klingebiel, Thomas, Kreuz, Wolfhart, MD

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Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial by Craig, Timothy J, Reshef, Avner, Li, H Henry, Jacobs, Joshua S, Bernstein, Jonathan A, Farkas, Henriette, Yang, William H, Stroes, Erik S G, Ohsawa, Isao, Tachdjian, Raffi, Manning, Michael E, Lumry, William R, Saguer, Inmaculada Martinez, Aygören-Pürsün, Emel, Ritchie, Bruce, Sussman, Gordon L, Anderson, John, Kawahata, Kimito, Suzuki, Yusuke, Staubach, Petra, Treudler, Regina, Feuersenger, Henrike, Glassman, Fiona, Jacobs, Iris, Magerl, Markus

“…Hereditary angioedema is a rare and potentially life-threatening genetic disease that is associated with kallikrein–kinin system dysregulation. Garadacimab…”
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The influence of individualized treatment on the quality of life (QoL) in 100 patients with Hereditary Angioedema (HAE C1-INH) by Saguer, Inmaculada Martinez, Ettingshausen, Carmen Escuriola, Gutowski, Zeynep, Linde, Richard

“…Methods A patient questionnaire was developed in order to evaluate QoL of the patients, type of treatment and how they deal with their current therapeutic…”
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Validation of the Angioedema Control Test (AECT)—A Patient-Reported Outcome Instrument for Assessing Angioedema Control by Weller, Karsten, Donoso, Tamara, Magerl, Markus, Aygören-Pürsün, Emel, Staubach, Petra, Martinez-Saguer, Inmaculada, Hawro, Tomasz, Altrichter, Sabine, Krause, Karoline, Siebenhaar, Frank, Metz, Martin, Zuberbier, Torsten, Freier, Denise, Maurer, Marcus

“…Recurrent angioedema (RA) is an important clinical problem in routine care and emergency medicine. As of recently, the only validated tools to specifically…”
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Home therapy with intravenous human C1-inhibitor in children and adolescents with hereditary angioedema by Kreuz, Wolfhart, Rusicke, Eva, Martinez-Saguer, Inmaculada, Aygören-Pürsün, Emel, Heller, Christine, Klingebiel, Thomas

“…BACKGROUND: C1‐esterase inhibitor (C1‐INH) replacement therapy is the treatment of choice for acute edema attacks in patients with hereditary angioedema (HAE)…”
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