Search Results - "Martinez Martinez, Fernando"

Early-Life Origins of Chronic Obstructive Pulmonary Disease by Martinez, Fernando D

“…The conventional thinking about COPD is that exposures in adult life, such as smoking, lead to a low FEV 1 :FVC ratio, the physiological hallmark of COPD. In…”
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Severe Covid-19 by Berlin, David A, Gulick, Roy M, Martinez, Fernando J

“…Patients with severe Covid-19 should have close monitoring for the need for endotracheal intubation; intubated patients should receive lung-protective…”
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Alternative Activation of Macrophages: Mechanism and Functions by Gordon, Siamon, Martinez, Fernando O.

“…The concept of an alternative pathway of macrophage activation has stimulated interest in its definition, mechanism, and functional significance in homeostasis…”
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Macrophage heterogeneity in tissues: phenotypic diversity and functions by Gordon, Siamon, Plüddemann, Annette, Martinez Estrada, Fernando

“…Summary During development and throughout adult life, macrophages derived from hematopoietic progenitors are seeded throughout the body, initially in the…”
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The M1 and M2 paradigm of macrophage activation: time for reassessment by Martinez, Fernando O, Gordon, Siamon

“…Macrophages are endowed with a variety of receptors for lineage-determining growth factors, T helper (Th) cell cytokines, and B cell, host, and microbial…”
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The role of the microbiome in exacerbations of chronic lung diseases by Dickson, Robert P, MD, Martinez, Fernando J, Prof, Huffnagle, Gary B, Prof

“…Summary Culture-independent microbiological techniques have shown a previously unappreciated complexity to the bacterial microbiome of the respiratory tract…”
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Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells by Kimura, Hiroki, Francisco, Dave, Conway, Michelle, Martinez, Fernando D., Vercelli, Donata, Polverino, Francesca, Billheimer, Dean, Kraft, Monica

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has dramatically changed our world, country, communities, and families. There is controversy…”
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Reply to Gan et al by Martinez, Fernando J

“…Martinez read with interest the comments of Gan et al regarding their phase IIB study of the cystic fibrosis transmembrane conductance regulator (CFTR)…”
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Idiopathic Pulmonary Fibrosis by Lederer, David J, Martinez, Fernando J

“…Idiopathic pulmonary fibrosis appears to be increasing in incidence. It requires early recognition and intervention with supportive care and pharmacologic…”
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Alternative activation of macrophages: an immunologic functional perspective by Martinez, Fernando O, Helming, Laura, Gordon, Siamon

“…Macrophages are innate immune cells with well-established roles in the primary response to pathogens, but also in tissue homeostasis, coordination of the…”
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Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease by Halpin, David M G, Criner, Gerard J, Papi, Alberto, Singh, Dave, Anzueto, Antonio, Martinez, Fernando J, Agusti, Alvar A, Vogelmeier, Claus F

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has raised many questions about the management of patients with chronic obstructive…”
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The Microbiome and the Respiratory Tract by Dickson, Robert P, Erb-Downward, John R, Martinez, Fernando J, Huffnagle, Gary B

“…Although the notion that "the normal lung is free from bacteria" remains common in textbooks, it is virtually always stated without citation or argument. The…”
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Genetic mutations in RNA-binding proteins and their roles in ALS by Kapeli, Katannya, Martinez, Fernando J., Yeo, Gene W.

“…Mutations in genes that encode RNA-binding proteins (RBPs) have emerged as critical determinants of neurological diseases, especially motor neuron disorders…”
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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines by Murray, Peter J., Allen, Judith E., Biswas, Subhra K., Fisher, Edward A., Gilroy, Derek W., Goerdt, Sergij, Gordon, Siamon, Hamilton, John A., Ivashkiv, Lionel B., Lawrence, Toby, Locati, Massimo, Mantovani, Alberto, Martinez, Fernando O., Mege, Jean-Louis, Mosser, David M., Natoli, Gioacchino, Saeij, Jeroen P., Schultze, Joachim L., Shirey, Kari Ann, Sica, Antonio, Suttles, Jill, Udalova, Irina, van Ginderachter, Jo A., Vogel, Stefanie N., Wynn, Thomas A.

“…Description of macrophage activation is currently contentious and confusing. Like the biblical Tower of Babel, macrophage activation encompasses a panoply of…”
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Asthma in the Time of COVID-19 by Martinez, Fernando D

“…During the last 15 months, all human activity has been profoundly affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The…”
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Strengthening patients' triage in community pharmacies: A cluster randomised controlled trial to evaluate the clinical impact of a minor ailment service by Amador-Fernández, Noelia, Benrimoj, Shalom I, Olry de Labry Lima, Antonio, García-Cárdenas, Victoria, Gastelurrutia, Miguel Ángel, Berger, Jérôme, Baixauli-Fernández, Vicente J, Climent-Catalá, María Teresa, Colomer-Molina, Vicente, Martínez-Martínez, Fernando

“…Self-perceived minor ailments might conceal other health conditions if patients are not appropriately assisted by health care professionals. The aim of the…”
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Regulators of macrophage activation by Martinez, Fernando O.

“…Macrophages are ubiquitous phagocytes that can constitute up to 15% of the cellular content of tissues. These heterogeneous cells of the innate immune system…”
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After asthma: redefining airways diseases by Pavord, Ian D, Beasley, Richard, Agusti, Alvar, Anderson, Gary P, Bel, Elisabeth, Brusselle, Guy, Cullinan, Paul, Custovic, Adnan, Ducharme, Francine M, Fahy, John V, Frey, Urs, Gibson, Peter, Heaney, Liam G, Holt, Patrick G, Humbert, Marc, Lloyd, Clare M, Marks, Guy, Martinez, Fernando D, Sly, Peter D, von Mutius, Erika, Wenzel, Sally, Zar, Heather J, Bush, Andy

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Pulmonary hypertension in chronic lung disease and hypoxia by Nathan, Steven D, Barbera, Joan A, Gaine, Sean P, Harari, Sergio, Martinez, Fernando J, Olschewski, Horst, Olsson, Karen M, Peacock, Andrew J, Pepke-Zaba, Joanna, Provencher, Steeve, Weissmann, Norbert, Seeger, Werner

“…Pulmonary hypertension (PH) frequently complicates the course of patients with various forms of chronic lung disease (CLD). CLD-associated PH (CLD-PH) is…”
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Childhood Asthma Inception and Progression: Role of Microbial Exposures, Susceptibility to Viruses and Early Allergic Sensitization by Martinez, Fernando D

“…Inappropriate responses to respiratory viruses, especially rhinovirus, and early allergic sensitization are the strongest contributors to the inception and…”
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