Search Results - "Martinez‐Valbuena, Ivan"

Misfolded α‐Synuclein in Cerebrospinal Fluid of Contact Sport Athletes by Vasilevskaya, Anna, Martinez‐Valbuena, Ivan, Anastassiadis, Chloe, Taghdiri, Foad, Khodadadi, Mozhgan, Tarazi, Apameh, Green, Robin, Colella, Brenda, Wennberg, Richard, Mikulis, David, Davis, Karen Deborah, Kovacs, Gabor G., Tator, Charles, Tartaglia, Maria Carmela

“…Background Misfolded α‐synuclein in Parkinson's disease (PD) and dementia with Lewy bodies (DLB) can be detected using the real‐time quaking‐induced conversion…”
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Misfolded α‐Synuclein Seeding Is Detected in Suspected LRRK2‐Parkinson's Disease without Immunohistochemically Detectable α‐Synuclein Pathology by Kim, Ain, Martinez‐Valbuena, Ivan, Keith, Julia L., Kovacs, Gabor G., Lang, Anthony E.

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Combining Skin α‐Synuclein Real‐Time Quaking‐Induced Conversion and Circulating Neurofilament Light Chain to Distinguish Multiple System Atrophy and Parkinson's Disease by Martinez‐Valbuena, Ivan, Visanji, Naomi P., Olszewska, Diana A., Sousa, Mario, Bhakta, Puja, Vasilevskaya, Anna, Anastassiadis, Chloe, Tartaglia, Maria Carmela, Kovacs, Gabor G., Lang, Anthony E.

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Amylin as a potential link between type 2 diabetes and alzheimer disease by Martinez‐Valbuena, Ivan, Valenti‐Azcarate, Rafael, Amat‐Villegas, Irene, Riverol, Mario, Marcilla, Irene, Andrea, Carlos E., Sánchez‐Arias, Juan Antonio, Mar Carmona‐Abellan, Maria, Marti, Gloria, Erro, Maria‐Elena, Martínez‐Vila, Eduardo, Tuñon, Maria‐Teresa, Luquin, Maria‐Rosario

“…Objective Alzheimer disease (AD) is the leading cause of dementia, and although its etiology remains unclear, it seems that type 2 diabetes mellitus (T2DM) and…”
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Cell‐Specific Dysregulation of Iron and Oxygen Homeostasis as a Novel Pathophysiology in PSP by Lee, Seojin, Martinez‐Valbuena, Ivan, Andrea, Carlos E., Villalba‐Esparza, Maria, Ilaalagan, Suganthini, Couto, Blas, Visanji, Naomi P., Lang, Anthony E., Kovacs, Gabor G.

“…Objective Progressive supranuclear palsy (PSP) is a 4R‐tauopathy showing heterogeneous tau cytopathology commencing in the globus pallidus (GP) and the…”
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Protracted course progressive supranuclear palsy by Couto, Blas, Martinez‐Valbuena, Ivan, Lee, Seojin, Alfradique‐Dunham, Isabel, Perrin, Richard J., Perlmutter, Joel S., Cruchaga, Carlos, Kim, Ain, Visanji, Naomi, Sato, Christine, Rogaeva, Ekaterina, Lang, Anthony E., Kovacs, Gabor G.

“…Background and purpose Progressive supranuclear palsy (PSP) encompasses a broader range of disease courses than previously appreciated. The most frequent…”
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Ageing‐related tau astrogliopathy severely affecting the substantia nigra by Tanaka, Hidetomo, Lee, Seojin, Martinez‐Valbuena, Ivan, Couto, Blas, Tartaglia, Maria Carmela, Gordoa, Javier Sanchez‐Ruiz, Erro, M. Elena, Lang, Anthony E., Forrest, Shelley L., Kovacs, Gabor G.

“…Aims Astrocytic tau pathology is a major feature of tauopathies and ageing‐related tau astrogliopathy (ARTAG). The substantia nigra (SN) is one of the…”
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Alpha‐Synuclein RT‐QuIC in Idiopathic Normal Pressure Hydrocephalus by Fasano, Alfonso, Martinez‐Valbuena, Ivan, Azevedo, Paula, Silva, Carolina Candeias, Algarni, Musleh, Vasilevskaya, Anna, Anastassiadis, Chloe, Taghdiri, Foad, Kongkham, Paul, Radovanovic, Ivan, Zadeh, Gelareh, Lang, Anthony E., Tang‐Wai, David F., Kovacs, Gabor G., Tartaglia, Maria Carmela

“…This study quantified the occurrence of an underlying synucleinopathy in 50 patients with idiopathic normal pressure hydrocephalus by means of real‐time…”
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Neuronal SNCA transcription during Lewy body formation by Kon, Tomoya, Forrest, Shelley L., Lee, Seojin, Martinez‑Valbuena, Ivan, Li, Jun, Nassir, Nasna, Uddin, Mohammed J., Lang, Anthony E., Kovacs, Gabor G.

“…Misfolded α-synuclein (α-syn) is believed to contribute to neurodegeneration in Lewy body disease (LBD) based on considerable evidence including a gene-dosage…”
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Alpha-Synuclein in Peripheral Tissues as a Possible Marker for Neurological Diseases and Other Medical Conditions by Jiménez-Jiménez, Félix Javier, Alonso-Navarro, Hortensia, García-Martín, Elena, Santos-García, Diego, Martínez-Valbuena, Iván, Agúndez, José A. G

“…The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues (blood cells, salivary gland biopsies, olfactory mucosa, digestive…”
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Phenotype parallels protein seeding capacity in neurodegenerative diseases by Martinez‐Valbuena, Ivan

“…With the new era of disease‐modifying therapies for neurodegenerative diseases, a novel approach for the molecular classification of neurodegenerative diseases…”
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Dream Enactment Behavior Disorder Associated with Pallido‐Nigro‐Luysian Degeneration and Tau Proteinopathy by Di Luca, Daniel G., Slow, Elizabeth J., Martinez‐Valbuena, Ivan, Lang, Anthony E., Kovacs, Gabor G.

“…ABSTRACT Background Pallido‐nigro‐luysian atrophy (PNLA) is a rare neurodegenerative disorder with only a few cases reported to date. Although the clinical…”
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Cellular iron deposition patterns predict clinical subtypes of multiple system atrophy by Lee, Seojin, Martinez-Valbuena, Ivan, Lang, Anthony E., Kovacs, Gabor G.

“…Multiple system atrophy (MSA) is a primary oligodendroglial synucleinopathy, characterized by elevated iron burden in early-affected subcortical nuclei…”
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Interictal amylin levels in chronic migraine patients: A case-control study by Irimia, Pablo, Martínez-Valbuena, Iván, Mínguez-Olaondo, Ane, Domínguez-Vivero, Clara, Sánchez-Arias, Juan-Antonio, Martínez-Vila, Eduardo, Luquin, María-Rosario, Leira, Rogelio

“…Recently, amylin and its receptors were found in different structures involved in migraine pathophysiology. Here, we evaluate interictal concentrations of…”
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Distinct Molecular Signatures of Amyloid-Beta and Tau in Alzheimer's Disease Associated with Down Syndrome by Ichimata, Shojiro, Martinez-Valbuena, Ivan, Lee, Seojin, Li, Jun, Karakani, Ali M, Kovacs, Gabor G

“…Limited comparative data exist on the molecular spectrum of amyloid-beta (Aβ) and tau deposition in individuals with Down syndrome (DS) and sporadic…”
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Molecular Behavior of α-Synuclein Is Associated with Membrane Transport, Lipid Metabolism, and Ubiquitin-Proteasome Pathways in Lewy Body Disease by Kon, Tomoya, Lee, Seojin, Martinez-Valbuena, Ivan, Yoshida, Koji, Tanikawa, Satoshi, Lang, Anthony E, Kovacs, Gabor G

“…Lewy body diseases (LBDs) feature α-synuclein (α-syn)-containing Lewy bodies, with misfolded α-syn potentially propagating as seeds. Using a seeding…”
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An amygdala-cingulate network underpins changes in effort-based decision making after a fitness program by Bernacer, Javier, Martinez-Valbuena, Ivan, Martinez, Martin, Pujol, Nuria, Luis, Elkin O., Ramirez-Castillo, David, Pastor, Maria A.

“…When humans make decisions, objective rewards are mainly discounted by delay, risk and effort. Whereas recent research has demonstrated that several brain…”
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Alpha-synuclein seeding shows a wide heterogeneity in multiple system atrophy by Martinez-Valbuena, Ivan, Visanji, Naomi P, Kim, Ain, Lau, Heather H C, So, Raphaella W L, Alshimemeri, Sohaila, Gao, Andrew, Seidman, Michael A, Luquin, Maria R, Watts, Joel C, Lang, Anthony E, Kovacs, Gabor G

“…Multiple system atrophy (MSA) is a neurodegenerative condition characterized by variable combinations of parkinsonism, autonomic failure, cerebellar ataxia and…”
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Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology by Kovacs, Gabor G, Grinberg, Lea T, Halliday, Glenda, Alafuzoff, Irina, Dugger, Brittany N, Murayama, Shigeo, Forrest, Shelley L, Martinez-Valbuena, Ivan, Tanaka, Hidetomo, Kon, Tomoya, Yoshida, Koji, Jaunmuktane, Zane, Spina, Salvatore, Nelson, Peter T, Gentleman, Steve, Alegre-Abarrategui, Javier, Serrano, Geidy E, Paes, Vitor Ribeiro, Takao, Masaki, Wakabayashi, Koichi, Uchihara, Toshiki, Yoshida, Mari, Saito, Yuko, Kofler, Julia, Rodriguez, Roberta Diehl, Gelpi, Ellen, Attems, Johannes, Crary, John F, Seeley, William W, Duda, John E, Keene, C Dirk, Woulfe, John, Munoz, David, Smith, Colin, Lee, Edward B, Neumann, Manuela, White, 3rd, Charles L, McKee, Ann C, Thal, Dietmar R, Jellinger, Kurt, Ghetti, Bernardino, Mackenzie, Ian R A, Dickson, Dennis W, Beach, Thomas G

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Cardiac sympathetic innervation in the MPTP non-human primate model of Parkinson disease by Carmona-Abellan, Mar, Martínez-Valbuena, Ivan, DiCaudo, Carla, Marcilla, Irene, Luquin, Maria Rosario

“…Purpose Systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces degeneration of dopaminergic neurons and reproduces the motor…”
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