Search Results - "Martinez‐Brito, Dayamin"

LC‐HRMS‐based metabolomics workflow: An alternative strategy for metabolite identification in the antidoping field by Leogrande, Patrizia, Jartdines, Daniel, Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale The proposed metabolomic workflow, based on coupling high‐resolution mass spectrometry with computational tools, can be an alternative strategy for…”
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Detection of urinary metabolites of arimistane in humans by gas chromatography coupled to high‐accuracy mass spectrometry for antidoping analyses by Martinez Brito, Dayamin, Torre, Xavier, Botrè, Francesco

“…Rationale The selection of the most appropriate metabolites of the substances included in the Prohibited List of the World Anti‐Doping Agency (WADA) is…”
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Investigation of the Physiological and Post‐training Effects of Ecdysteroid Supplementation by Multivariate Analysis of the Human Serum Metabolome by Leogrande, Patrizia, Jardines, Daniel, Brito, Dayamin Martinez, Torre, Xavier, Botrè, Francesco, Luch, Andreas, Diel, Patrick, Parr, Maria Kristina

“…ABSTRACT This work aims to characterize the serum profile of athletes after the administration of ecdysteroids, natural steroid hormones recently reported to…”
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A further insight into methyltestosterone metabolism: New evidences from in vitro and in vivo experiments by Martinez‐Brito, Dayamin, Iannone, Michele, Tatangelo, Maria Antonietta, Molaioni, Francesco, Torre, Xavier, Botrè, Francesco

“…Rationale Although the metabolism of methyltestosterone (MT) has been extensively studied since the 1950s using different techniques, the aim of this study was…”
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Detection of urinary arimistane metabolites in humans using liquid chromatography–mass spectrometry: Complementary results to gas chromatography mass spectrometric data and its application to antidoping analyses by Martinez Brito, Dayamin, Leogrande, Patrizia, Botrè, Francesco, Torre, Xavier

“…Rationale The metabolism of arimistane (Arim) was first described in 2015, and androst‐3,5‐diene‐7β‐ol‐17‐one was proposed as the main metabolite excreted in…”
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Mass spectrometric analysis of 7‐oxygenated androst‐5‐ene structures. Influence in trimethylsilyl derivative formation by Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale Several authors have described the generation of androsta‐3,5‐diene‐7‐one structures from androst‐5‐ene‐3,7‐dione or androst‐5‐ene‐3β‐ol‐7‐one under…”
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7‐keto‐DHEAmetabolism in humans. Pitfalls in interpreting the analytical results in the antidoping field by Martinez‐Brito, Dayamin, Torre, Xavier, Colamonici, Cristiana, Curcio, Davide, Botrè, Francesco

“…7‐keto‐DHEA (3β‐hydroxy‐androst‐5‐ene‐7,17‐dione) is included in section S1 of the World Antidoping Agency (WADA) List of Prohibited Substances. The detection…”
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Detection of thyroid hormones in urine by liquid chromatography coupled to tandem mass spectrometry by Martinez Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Botrè, Francesco

“…Recently, the trend of thyroid hormones (TH) consumption in the sports community has been published. It is known the capacity of the exogenously administered…”
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Characterization of the thyroid hormones level in urine by liquid chromatography coupled to mass spectrometry focus in the antidoping field by Martínez Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Romanelli, Francesco, Botrè, Francesco

“…This paper aims to study the metabolism of thyroid hormones (TH) in urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The method was applied…”
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Metabolomics workflow as a driven tool for rapid detection of metabolites in doping analysis. Development and validation by Leogrande, Patrizia, Jardines, Daniel, Martinez‐Brito, Dayamin, Domenici, Eleonora, Torre, Xavier, Parr, Maria Kristina, Botrè, Francesco

“…Rationale This work demonstrates the high potential of combining high‐resolution mass spectrometry with chemometric tools, using metabolomics as a guided tool…”
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Low‐energy electron ionization optimization for steroidomics analysis using high‐resolution mass spectrometry by Leogrande, Patrizia, Jardines, Daniel, Martinez‐Brito, Dayamin, Torre, Xavier, Parr, Maria K., Botrè, Francesco

“…Rationale Systematic electron ionization fragmentation studies of steroids have been performed to elucidate and trace their characteristic fragmentation…”
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Optimization of a method to detect levothyroxine and related compounds in serum and urine by liquid chromatography coupled to triple quadrupole mass spectrometry by Martínez_Brito, Dayamin, Leogrande, Patrizia, de la Torre, Xavier, Botrè, Francesco

“…Thyroid hormones and their derivatives are structurally related to the non-essential amino acid tyrosine (4-hydroxyphenylalanine). However, there are…”
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Quantification of thyroid hormones and analogs by liquid chromatography coupled to mass spectrometry. Preliminary results in athletes and non‐athletes serum samples by Martínez Brito, Dayamin, Leogrande, Patrizia, Donati, Francesco, Torre, Xavier, Botrè, Francesco

“…This paper aimed to assess a method to measure eight thyroid‐related compounds in serum by liquid chromatography‐mass spectrometry (LC‐MS/MS), to verify the…”
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Thyroid metabolism and supplementation: A review framed in sports environment by Martínez Brito, Dayamin, Botrè, Francesco, Romanelli, Francesco, Torre, Xavier

“…Objectives This paper aimed to consider those features that may suggest a link between thyroid hormones pharmacology and athletes' health based on current…”
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Gas chromatography/mass spectrometry characterization of urinary metabolites of danazol after oral administration in human by de Oca Porto, Rodny Montes, Fernández, Ariana Rodríguez, Brito, Dayamín Martínez, Vidal, Teresa Correa, Diaz, Ahiram Lopez

“…Danazol (17α-pregna-2,4-dien-20-yno [2,3-d]-isoxazol-17β-ol), is a synthetic derivative of ethisterone, structurally related to stanozolol. For this reason its…”
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Effect of thyroid hormones administration on urinary endogenous steroid profile of the athlete biological passport by Martínez_Brito, Dayamin, Torre, Xavier, Botrè, Francesco

“…This work focused on the possible alterations of the markers of the steroidal module of the athlete biological passport, considering samples of athletes…”
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Development and application of analytical procedures for the GC–MS/MS analysis of the sulfates metabolites of anabolic androgenic steroids: The pivotal role of chemical hydrolysis by Iannone, Michele, Botrè, Francesco, Martinez-Brito, Dayamin, Matteucci, Roberta, de la Torre, Xavier

“…•Chemical and enzymatic hydrolysis of sulfate moiety have been evaluated.•Different extraction methods for isolation of sulfate steroids are taking into…”
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Arimistane: Degradation product or metabolite of 7‐oxo‐DHEA? by Martínez Brito, Dayamín, Leogrande, Patrizia, Colamonici, Cristiana, Curcio, Davide, Botre, Francesco, Torre, Xavier

“…Rationale The instability of androst‐5‐ene‐3,7‐dione structures under acidic conditions is known. The formation of arimistane from 7‐oxo‐DHEA, influenced by…”
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Correction of the urinary testosterone to epitestosterone ratio measurement in antidoping analyses by chromatographic and mass spectrometric techniques by Martínez Brito, Dayamín, Vidal, Teresa Correa, Torre, Xavier, Oca Porto, Rodny Montes, Botrè, Francesco

“…The ratio of testosterone (T) to epitestosterone (E) determined in urine samples is the main biomarker used to prove T and precursors abused by athletes…”
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Carbon isotope ratio of endogenous urinary steroids of the Cuban population of athletes studied for doping purposes by Montes de Oca Porto, Rodny, Fernández_Hormiga, Miguel Angel, Correa_Vidal, Margarita Teresa, Martínez_Brito, Dayamin

“…The aim of this work was to validate the gas chromatography/combustion/isotope ratio mass spectrometry method in Havana Antidoping Laboratory and verify its…”
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