Search Results - "Martinez, Michael A Q"

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans by Medwig-Kinney, Taylor N, Kinney, Brian A, Martinez, Michael A Q, Yee, Callista, Sirota, Sydney S, Mullarkey, Angelina A, Somineni, Neha, Hippler, Justin, Zhang, Wan, Shen, Kang, Hammell, Christopher, Pani, Ariel M, Matus, David Q

“…A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between…”
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CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle by Martinez, Michael A Q, Matus, David Q

“…Cyclin-dependent kinase (CDK) sensors have facilitated investigations of the cell cycle in living cells. These genetically encoded fluorescent biosensors…”
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An expanded auxin-inducible degron toolkit for Caenorhabditis elegans by Ashley, Guinevere E, Duong, Tam, Levenson, Max T, Martinez, Michael A Q, Johnson, Londen C, Hibshman, Jonathan D, Saeger, Hannah N, Palmisano, Nicholas J, Doonan, Ryan, Martinez-Mendez, Raquel, Davidson, Brittany R, Zhang, Wan, Ragle, James Matthew, Medwig-Kinney, Taylor N, Sirota, Sydney S, Goldstein, Bob, Matus, David Q, Dickinson, Daniel J, Reiner, David J, Ward, Jordan D

“…Abstract The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally deplete proteins in a range of organisms and cell types. Here,…”
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The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo by Smith, Jayson J, Xiao, Yutong, Parsan, Nithin, Medwig-Kinney, Taylor N, Martinez, Michael A Q, Moore, Frances E Q, Palmisano, Nicholas J, Kohrman, Abraham Q, Chandhok Delos Reyes, Mana, Adikes, Rebecca C, Liu, Simeiyun, Bracht, Sydney A, Zhang, Wan, Wen, Kailong, Kratsios, Paschalis, Matus, David Q

“…Chromatin remodelers such as the SWI/SNF complex coordinate metazoan development through broad regulation of chromatin accessibility and transcription,…”
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Visualizing the metazoan proliferation-quiescence decision in vivo by Adikes, Rebecca C, Kohrman, Abraham Q, Martinez, Michael A Q, Palmisano, Nicholas J, Smith, Jayson J, Medwig-Kinney, Taylor N, Min, Mingwei, Sallee, Maria D, Ahmed, Ononnah B, Kim, Nuri, Liu, Simeiyun, Morabito, Robert D, Weeks, Nicholas, Zhao, Qinyun, Zhang, Wan, Feldman, Jessica L, Barkoulas, Michalis, Pani, Ariel M, Spencer, Sabrina L, Martin, Benjamin L, Matus, David Q

“…Cell proliferation and quiescence are intimately coordinated during metazoan development. Here, we adapt a cyclin-dependent kinase (CDK) sensor to uncouple…”
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Rapid Degradation of Caenorhabditis elegans Proteins at Single-Cell Resolution with a Synthetic Auxin by Martinez, Michael A Q, Kinney, Brian A, Medwig-Kinney, Taylor N, Ashley, Guinevere, Ragle, James M, Johnson, Londen, Aguilera, Joseph, Hammell, Christopher M, Ward, Jordan D, Matus, David Q

“…As developmental biologists in the age of genome editing, we now have access to an ever-increasing array of tools to manipulate endogenous gene expression. The…”
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Reevaluating the relationship between EGL-43 (EVI1) and LIN-12 (Notch) during C. elegans anchor cell invasion by Martinez, Michael A Q, Mullarkey, Angelina A, Yee, Callista, Zhao, Chris Z, Zhang, Wan, Shen, Kang, Matus, David Q

“…Development of the Caenorhabditis elegans reproductive tract is orchestrated by the anchor cell (AC). This occurs in part through a cell invasion event that…”
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A membrane reticulum, the centriculum, affects centrosome size and function in Caenorhabditis elegans by Maheshwari, Richa, Rahman, Mohammad M., Drey, Seth, Onyundo, Megan, Fabig, Gunar, Martinez, Michael A.Q., Matus, David Q., Müller-Reichert, Thomas, Cohen-Fix, Orna

“…Centrosomes are cellular structures that nucleate microtubules. At their core is a pair of centrioles that recruit pericentriolar material (PCM). Although…”
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An expandable FLP-ON::TIR1 system for precise spatiotemporal protein degradation in Caenorhabditis elegans by Xiao, Yutong, Yee, Callista, Zhao, Chris Z, Martinez, Michael A Q, Zhang, Wan, Shen, Kang, Matus, David Q, Hammell, Christopher

“…Abstract The auxin-inducible degradation system has been widely adopted in the Caenorhabditis elegans research community for its ability to empirically control…”
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An engineered, orthogonal auxin analog/ At TIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans by Hills-Muckey, Kelly, Martinez, Michael A Q, Stec, Natalia, Hebbar, Shilpa, Saldanha, Joanne, Medwig-Kinney, Taylor N, Moore, Frances E Q, Ivanova, Maria, Morao, Ana, Ward, J D, Moss, Eric G, Ercan, Sevinc, Zinovyeva, Anna Y, Matus, David Q, Hammell, Christopher M

“…Abstract The auxin-inducible degradation system in C. elegans allows for spatial and temporal control of protein degradation via heterologous expression of a…”
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Cell cycle perturbation uncouples mitotic progression and invasive behavior in a post-mitotic cell by Martinez, Michael A.Q., Zhao, Chris Z., Moore, Frances E.Q., Yee, Callista, Zhang, Wan, Shen, Kang, Martin, Benjamin L., Matus, David Q.

“…The acquisition of the post-mitotic state is crucial for the execution of many terminally differentiated cell behaviors during organismal development. However,…”
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Auxin-mediated Protein Degradation in Caenorhabditis elegans by Martinez, Michael A Q, Matus, David Q

“…The auxin-inducible degron (AID) technology was recently adapted for use in the nematode . Rapid degradation of proteins tagged with an AID is mediated by a…”
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An engineered, orthogonal auxin analog/AtTIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans by Hills-Muckey, Kelly, Martinez, Michael A Q, Stec, Natalia, Hebbar, Shilpa, Saldanha, Joanne, Medwig-Kinney, Taylor N, Moore, Frances E Q, Ivanova, Maria, Morao, Ana, Ward, J D, Moss, Eric G, Ercan, Sevinc, Zinovyeva, Anna Y, Matus, David Q, Hammell, Christopher M

“…Abstract The auxin-inducible degradation system in C. elegans allows for spatial and temporal control of protein degradation via heterologous expression of a…”
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The Relationship Between Cell Invasion and Proliferation in C. elegans by Martinez, Michael A. Q

“…According to the invasion/proliferation dichotomy, which is generally referred to as the “go versus grow” dichotomy, cell invasion and proliferation are…”
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Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans by Medwig-Kinney, Taylor N, Kinney, Brian A, Martinez, Michael AQ, Yee, Callista, Sirota, Sydney S, Mullarkey, Angelina A, Somineni, Neha, Hippler, Justin, Zhang, Wan, Shen, Kang, Hammell, Christopher, Pani, Ariel M, Matus, David Q

“…A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between…”
Get full text