Search Results - "Martinez, Gláucia Regina"
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Structure and intracellular antioxidant activity of pectic polysaccharide from acerola (Malpighia emarginata)
Published in International journal of biological macromolecules (01-01-2018)“…Malpighia emarginata is a tropical fruit plant, found naturally in the Caribbean islands and South America that produces an edible fruit known as acerola or…”
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Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: Antioxidants, lipid peroxidation and DNA damage
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-04-2007)“…Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative…”
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Effects of the melanin precursor 5,6-dihydroxy-indole-2-carboxylic acid (DHICA) on DNA damage and repair in the presence of reactive oxygen species
Published in Archives of biochemistry and biophysics (01-09-2014)“…•DHICA causes single strand breaks in plasmid DNA in the absence of light radiation.•DHICA oxidized by 1O2 loses the capacity to induce DNA damage.•DHICA…”
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Selective Cytotoxicity of 1,3,4-Thiadiazolium Mesoionic Derivatives on Hepatocarcinoma Cells (HepG2)
Published in PloS one (17-06-2015)“…In this work, we evaluated the cytotoxicity of mesoionic 4-phenyl-5-(2-Y, 4-X or 4-X-cinnamoyl)-1,3,4-thiadiazolium-2-phenylamine chloride derivatives (MI-J:…”
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Antioxidant effect of 1,3,4-thiadiazolium mesoionic derivatives on isolated mitochondria
Published in European journal of pharmacology (05-01-2016)“…Mesoionic compounds have shown antitumor and citotoxic activity against different tumor cells lines, which has been attributed to their physical and chemical…”
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Plasmid DNA damage induced by singlet molecular oxygen released from the naphthalene endoperoxide DHPNO2 and photoactivated methylene blue
Published in Química nova (2010)“…To investigate oxidative lesions and strand breaks induction by singlet molecular oxygen (¹O2), supercoiled-DNA plasmid was treated with thermo-dissociated…”
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Pectin from Brassica oleracea var. italica triggers immunomodulating effects in vivo
Published in International journal of biological macromolecules (15-10-2020)“…The immunomodulatory ability of pectins is related with structural features such as the degree of methyl-esterification and branching, as well as the molecular…”
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Unveiling novel targets in melanoma under melanogenesis stimulation and photodynamic therapy by redox proteomics
Published in Photochemistry and photobiology (04-07-2024)“…Melanogenesis-stimulated B16-F10 cells enter in a quiescent state, present inhibited mitochondrial respiration and increased reactive oxygen species levels…”
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Effects of redox modulation on quiescin/sulfhydryl oxidase activity of melanoma cells
Published in Molecular and cellular biochemistry (01-03-2024)“…Secreted quiescin/sulfhydryl oxidase (QSOX) is overexpressed in many tumor cell lines, including melanoma, and is usually associated with a pro-invasive…”
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High Melanin Content in Melanoma Cells Contributes to Enhanced DNA Damage after Rose Bengal Photosensitization
Published in Photochemistry and photobiology (01-11-2022)“…Melanoma is a type of tumor that originates from melanocytes. Irradiation of melanin with UVA and visible light can produce reactive oxygen species (ROS) such…”
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11
Modified pectin from Theobroma cacao induces potent pro-inflammatory activity in murine peritoneal macrophage
Published in International journal of biological macromolecules (01-11-2016)“…Studied pectins modulate macrophages.They presented distinct pattern on murine peritoneal macrophage activation.Acetylated pectin (OP) from cacao pod husks…”
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12
Mitochondrial bioenergetics and enzymatic antioxidant defense differ in Paraná pine cell lines with contrasting embryogenic potential
Published in Free radical research (04-03-2021)“…is classified as a critically endangered species by the International Union for Conservation of Nature. This threat is worsened by the inefficiency of methods…”
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The metabolic response of Araucaria angustifolia embryogenic cells to heat stress is associated with their maturation potential
Published in Functional plant biology : FPB (01-12-2023)“…Araucaria angustifolia is a critically endangered species and its distribution can be affected by an increase in temperature. In this study, we evaluated the…”
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Melanogenesis inhibits respiration in B16-F10 melanoma cells whereas enhances mitochondrial cell content
Published in Experimental cell research (01-01-2017)“…Melanoma is a rare and aggressive skin tumor; the survival of patients diagnosed late is fairly low. This high mortality rate is due to the characteristics of…”
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Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions
Published in Carbohydrate polymers (01-10-2017)“…•Galactomannan from S. amazonicum (SAGM) was modified by acidic hydrolysis (MSAGM).•SAGM and MSAGM were complexed with oxovanadium resulting in SAGM:VO and…”
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Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells
Published in International journal of biological macromolecules (01-01-2019)“…The aim of this study was to investigate the effects of xyloglucan extracted from Copaifera langsdorffii seeds (XGC) and its complex with oxovanadium (XGC:VO)…”
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The alternatively spliced RECK transcript variant 3 is a predictor of poor survival for melanoma patients being upregulated in aggressive cell lines and modulating MMP gene expression in vitro
Published in Melanoma research (01-06-2020)“…The reversion-inducing cysteine-rich protein with kazal motifs (RECK) gene was described as a tumor suppressor gene two decades ago. Recently, novel…”
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Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells
Published in International journal of biological macromolecules (01-08-2017)“…This study evaluated the effects of native galactomannan from Schizolobium amazonicum seeds and its sulfated forms on certain metabolic parameters of HepG2…”
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Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway
Published in Experimental cell research (15-11-2013)“…Recent studies demonstrated that simvastatin has antitumor properties in several types of cancer cells, mainly by inducing apoptosis and inhibiting growth. The…”
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Cytotoxic effects of 4′-hydroxychalcone on human neuroblastoma cells (SH-SY5Y)
Published in Toxicology in vitro (01-12-2019)“…Neuroblastoma is an aggressive form of cancer with high mortality. Hydroxychalcones have received considerable attention because of their cytotoxic activities…”
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