Search Results - "Martinez, Débora"
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Antidepressant-like activity of dehydrozingerone: Involvement of the serotonergic and noradrenergic systems
Published in Pharmacology, biochemistry and behavior (01-12-2014)“…Dehydrozingerone (DHZ) is a phenolic compound isolated from ginger rhizomes (Zingiber officinale). It is known for its diverse spectrum of biological…”
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2
Synthesis and antioxidant activity of new C-3 sulfenyl indoles
Published in Tetrahedron letters (01-09-2013)“…A convenient and efficient methodology for the synthesis of new C-3 sulfur-substituted indoles under CeCl3·7H2O promotion is reported. Model…”
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3
Base-free oxidation of thiols to disulfides using selenium ionic liquid
Published in Tetrahedron letters (02-02-2011)“…We present here the results on the use of 1-n-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)], in the synthesis of symmetrical disulfides starting…”
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4
Twice acting antioxidants: synthesis and antioxidant properties of selenium and sulfur-containing zingerone derivatives
Published in Tetrahedron letters (22-04-2015)“…[Display omitted] •Two new organochalcogen derivatives of zingerone were synthesised.•The antioxidant activities of these compounds were examined.•The phenol…”
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5
Antioxidant properties of (R)-Se-aryl thiazolidine-4-carboselenoate
Published in Chemico-biological interactions (25-09-2013)“…•(R)-Se-aryl thiazolidine-4-carboselenoate (Se-PTC) is a promising antioxidant compound.•Antioxidant activity of Se-PTC is influenced by the amino…”
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6
Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice
Published in Regulatory toxicology and pharmacology (01-12-2015)“…Selenium is an essential micronutrient with several biological roles in the human body, but supra nutritional consumption can cause toxic effects. The…”
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7
Frequency and spectrum of PIK3CA somatic mutations in breast cancer
Published in Breast cancer research : BCR (13-05-2020)“…The therascreen PIK3CA mutation assay and the alpha-specific PI3K inhibitor alpelisib are FDA-approved for identifying and treating patients with advanced…”
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8
A High Performing Conjugated Microporous Polymer Cathode for Practical Sodium Metal Batteries Using an Ammoniate as Electrolyte
Published in Advanced energy materials (01-07-2024)“…The development of room‐temperature sodium‐metal batteries (SMBs) presents a cost‐effective solution for both large‐scale energy storage and high‐energy…”
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9
Glycerol as a promoting and recyclable medium for catalyst-free synthesis of linear thioethers: new antioxidants from eugenol
Published in Green chemistry letters and reviews (01-12-2013)“…We describe herein the use of glycerol as an efficient and recyclable solvent for the addition of thiols to nonactivated alkenes. The catalyst-free reactions…”
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10
Correlative Biomarker Analysis of Intrinsic Subtypes and Efficacy Across the MONALEESA Phase III Studies
Published in Journal of clinical oncology (01-05-2021)“…The prognostic and predictive value of intrinsic subtypes in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast…”
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Palbociclib and Trastuzumab in HER2-Positive Advanced Breast Cancer: Results from the Phase II SOLTI-1303 PATRICIA Trial
Published in Clinical cancer research (15-11-2020)“…To assess palbociclib in combination with trastuzumab with or without endocrine therapy in patients with HER2-positive advanced breast cancer. PATRICIA is a…”
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12
In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation
Published in Cell metabolism (03-06-2014)“…Obesity and type 2 diabetes have a heritable component that is not attributable to genetic factors. Instead, epigenetic mechanisms may play a role. We have…”
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13
Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer
Published in Nature communications (01-03-2023)“…Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the ability of plasma ctDNA to capture complex tumor phenotypes with…”
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14
The role of nutrition on epigenetic modifications and their implications on health
Published in Biochimie (01-11-2012)“…Nutrition plays a key role in many aspects of health and dietary imbalances are major determinants of chronic diseases including cardiovascular disease,…”
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15
Synthesis of Allylic Amines by Asymmetric Transfer Hydrogenation of α,β-Unsaturated N‑(tert-Butylsulfinyl)imines
Published in Journal of organic chemistry (15-12-2017)“…Primary allylic amines with enantiomeric excesses from 97 to >99% were prepared by asymmetric transfer hydrogenation of α,β-unsaturated…”
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16
Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer
Published in EBioMedicine (01-01-2022)“…Both clinical and genomic data independently predict survival and treatment response in early-stage HER2-positive breast cancer. Here we present the…”
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17
Organochalcogen compounds from glycerol: Synthesis of new antioxidants
Published in Bioorganic & medicinal chemistry (01-11-2014)“…We describe here a simple method for the synthesis of glycerol derivatives containing an organochalcogen unit (Se, Te and S) using NaBH4 and PEG-400 as a…”
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18
A protocol for testing the stability of biochemical analytes. Technical document
Published in Clinical chemistry and laboratory medicine (26-11-2019)“…Stability of a measurand in a specimen is a function of the property variation over time in specific storage conditions, which can be expressed as a stability…”
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A stable anthraquinone-derivative cathode to develop sodium metal batteries: The role of ammoniates as electrolytes
Published in Journal of energy chemistry (01-02-2023)“…Sodium metal batteries based on ammoniates as electrolytes and a widely available and cost-effective organic compound (indanthrone blue) as a cathode material,…”
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Sulfur Dioxide and Sulfolane as Additives in Organic Electrolytes to Develop Room-Temperature Sodium Batteries
Published in Batteries (Basel) (01-09-2022)“…Sodium metal anodes have attracted great attention for the development of a next generation of high-energy batteries because of their high theoretical capacity…”
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