Search Results - "Martinez, Carlos M."
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Cell Volume Regulation Modulates NLRP3 Inflammasome Activation
Published in Immunity (Cambridge, Mass.) (21-09-2012)“…Cell volume regulation is a primitive response to alterations in environmental osmolarity. The NLRP3 inflammasome is a multiprotein complex that senses…”
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The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
Published in Nature immunology (01-08-2014)“…The NLRP3 inflammasome is involved in IL-1 production and pyroptosis. Pelegrín et al . demonstrate that it is also released extracellularly as a functional…”
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Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection
Published in Cell reports (Cambridge) (19-12-2017)“…Immune cells are equipped with a number of receptors that recognize sterile injury and pathogens. We find that host immune cells release ATP as an inflammatory…”
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Obesity is associated with a greater number of long-term post-COVID symptoms and poor sleep quality: A multicentre case-control study
Published in International journal of clinical practice (Esher) (01-12-2021)“…Obesity is a risk factor associated with higher mortality at the acute phase of COVID-19; however, its influence on post-COVID symptoms is not known. Our aim…”
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Ultrasound Therapy With High-Pressure Pulses Is Effective to Reduce the Effects of Collagenase-Induced Tendinopathy in Rat's Achilles Tendon
Published in Ultrasound in medicine & biology (01-09-2024)“…We propose an ultrasonic treatment for collagenase-induced tendinopathy in rat's Achilles tendon using pulses with a low number of cycles, high acoustic…”
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The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability
Published in Journal of experimental & clinical cancer research (29-04-2024)“…TP53, the most frequently mutated gene in human cancers, orchestrates a complex transcriptional program crucial for cancer prevention. While certain…”
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Photocatalytic reverse polarity Povarov reaction
Published in Chemical science (Cambridge) (28-08-2018)“…A visible light mediated iridium photocatalysed reverse polarity Povarov reaction of aryl imines and electron deficient alkenes is described. Operating a…”
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Defibrotide inhibits donor leucocyte‐endothelial interactions and protects against acute graft‐versus‐host disease
Published in Journal of cellular and molecular medicine (01-07-2020)“…Allogeneic hematopoietic stem cell transplantation (allo‐HCT) is an effective therapy for the treatment of high‐risk haematological malignant disorders and…”
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Silk fibroin scaffolds seeded with Wharton's jelly mesenchymal stem cells enhance re-epithelialization and reduce formation of scar tissue after cutaneous wound healing
Published in Stem cell research & therapy (27-04-2019)“…The treatment of extensive and/or chronic skin wounds is a widespread and costly public health problem. Mesenchymal stem cells (MSCs) have been proposed as a…”
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CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis
Published in eLife (02-11-2020)“…P2X7 receptor activation induces the release of different cellular proteins, such as CD14, a glycosylphosphatidylinositol (GPI)-anchored protein to the plasma…”
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Anxiety, depression and poor sleep quality as long-term post-COVID sequelae in previously hospitalized patients: A multicenter study
Published in The Journal of infection (01-10-2021)Get full text
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Efficiency of Machine Learning Algorithms for the Determination of Macrovesicular Steatosis in Frozen Sections Stained with Sudan to Evaluate the Quality of the Graft in Liver Transplantation
Published in Sensors (Basel, Switzerland) (12-03-2021)“…Liver transplantation is the only curative treatment option in patients diagnosed with end-stage liver disease. The low availability of organs demands an…”
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Optimizing cryopreservation conditions for use of fucosylated human mesenchymal stromal cells in anti-inflammatory/immunomodulatory therapeutics
Published in Frontiers in immunology (28-03-2024)“…Mesenchymal stem/stromal cells (MSCs) are being increasingly used in cell-based therapies due to their broad anti-inflammatory and immunomodulatory properties…”
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Retinal response to systemic inflammation differs between sexes and neurons
Published in Frontiers in immunology (07-02-2024)“…Neurological dysfunction and glial activation are common in severe infections such as sepsis. There is a sexual dimorphism in the response to systemic…”
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Galectin-3 as a marker of interstitial atrial remodelling involved in atrial fibrillation
Published in Scientific reports (12-01-2017)“…Remodelling in the atria could appear as a result of hypertension, diabetes or ischaemic heart disease. Galectin-3 (Gal-3) is a mediator of profibrotic…”
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Diazaspirononane Nonsaccharide Inhibitors of O‑GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders
Published in Journal of medicinal chemistry (25-11-2020)“…O-GlcNAcylation is a post-translational modification of tau understood to lower the speed and yield of its aggregation, a pathological hallmark of Alzheimer’s…”
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Evaluation of rat liver with ARFI elastography: In vivo and ex vivo study
Published in PloS one (23-05-2019)“…The aim of this study was to compare in vivo vs ex vivo liver stiffness in rats with acoustic radiation force impulse (ARFI) elastography using the…”
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Demineralized Bone Matrix Coating Si-Ca-P Ceramic Does Not Improve the Osseointegration of the Scaffold
Published in Materials (01-09-2018)“…The aim of this study was to manufacture and evaluate the effect of a biphasic calcium silicophosphate (CSP) scaffold ceramic, coated with a natural…”
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Enforced mesenchymal stem cell tissue colonization counteracts immunopathology
Published in npj Regenerative medicine (19-10-2022)“…Mesenchymal stem/stromal cells (MSCs) are distributed within all tissues of the body. Though best known for generating connective tissue and bone, these cells…”
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Melatonin as an Agent for Direct Pulp-Capping Treatment
Published in International journal of environmental research and public health (06-02-2020)“…Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on…”
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