Search Results - "Martineau‐Dussault, Marie‐Ève"
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A portrait of obstructive sleep apnea risk factors in 27,210 middle-aged and older adults in the Canadian Longitudinal Study on Aging
Published in Scientific reports (24-03-2022)“…Determining the prevalence and characteristics of individuals susceptible to present with obstructive sleep apnea (OSA) is essential for developing targeted…”
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Obstructive Sleep Apnea and the Brain: a Focus on Gray and White Matter Structure
Published in Current neurology and neuroscience reports (01-03-2021)“…Purpose of Review Obstructive sleep apnea is extremely prevalent in the elderly and may precipitate dementia. We review recent advances on gray and white…”
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Altered fornix integrity is associated with sleep apnea‐related hypoxemia in mild cognitive impairment
Published in Alzheimer's & dementia (01-06-2024)“…INTRODUCTION The limbic system is critical for memory function and degenerates early in the Alzheimer's disease continuum. Whether obstructive sleep apnea…”
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Obstructive Sleep Apnea and Cognitive Decline: A Review of Potential Vulnerability and Protective Factors
Published in Brain sciences (27-05-2021)“…Around 40% of dementia risk is attributable to modifiable risk factors such as physical inactivity, hypertension, diabetes and obesity. Recently, sleep…”
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REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals
Published in Alzheimer's research & therapy (08-09-2023)“…Abstract Background Rapid-eye movement (REM) sleep highly depends on the activity of cholinergic basal forebrain (BF) neurons and is reduced in Alzheimer’s…”
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Altered resting-state functional connectivity patterns in late middle-aged and older adults with obstructive sleep apnea
Published in Frontiers in neurology (19-06-2023)“…Obstructive sleep apnea (OSA) is increasingly recognized as a risk factor for cognitive decline, and has been associated with structural brain alterations in…”
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Medial temporal lobe and obstructive sleep apnea: Effect of sex, age, cognitive status and free-water
Published in NeuroImage clinical (01-01-2022)“…•We characterized the relationship between obstructive sleep apnea and medial temporal structures, while considering the potential impact of individual…”
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Association between risk of obstructive sleep apnea, inflammation and cognition after 45 years old in the Canadian Longitudinal Study on Aging
Published in Sleep medicine (01-03-2022)“…The association between obstructive sleep apnea and cognitive functioning is not yet fully understood and could be influenced by factors such as sex, age and…”
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Age- and sex-specific associations between obstructive sleep apnea risk and cognitive decline in middle-aged and older adults: A 3-year longitudinal analysis of the Canadian longitudinal study on aging
Published in Sleep medicine (01-12-2023)“…Whether obstructive sleep apnea (OSA) increases the risk of cognitive decline and how sex and age influence this association is not clear. Here, we…”
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Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers
Published in Sleep (New York, N.Y.) (11-07-2024)“…Abstract Study Objectives Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer’s disease (AD). In addition, APOE4 carriers may…”
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Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ 4 allele carriers
Published in Sleep (New York, N.Y.) (11-07-2024)“…Abstract Study Objectives Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer’s disease (AD). In addition, APOE4 carriers may…”
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Obstructive sleep apnea risk is associated with decreased executive processing speed in older women but not in men: A longitudinal analysis of the Canadian Longitudinal Study on Aging
Published in Alzheimer's & dementia (01-12-2022)“…Background Studies investigating the possible links between obstructive sleep apnea (OSA) and cognitive dysfunction have yet led to heterogenous results…”
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Association between default‐mode network and medial temporal lobe functional connectivity and episodic memory in late middle‐aged and older patients with obstructive sleep apnea
Published in Alzheimer's & dementia (01-06-2023)“…Background Obstructive sleep apnea (OSA) is associated with risk of cognitive decline in older adults. Our group previously observed that more severe OSA was…”
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Longitudinal medial temporal lobe gray matter volume and cognitive changes in late middle‐aged and older adults with treated and non‐treated obstructive sleep apnea
Published in Alzheimer's & dementia (01-12-2022)“…Background Neuroimaging studies in obstructive sleep apnea (OSA) have found both gray matter atrophy and hypertrophy in medial temporal lobe subregions, the…”
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Obstructive sleep apnea in older adults: Differential cognitive impairment moderated by sex?
Published in Alzheimer's & dementia (01-12-2020)“…Background Obstructive sleep apnea (OSA) is a risk factor for cognitive decline, but the effect of sex on this association is unknown. This study aims at…”
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Obstructive sleep apnea in older adults: Differential cognitive impairment moderated by sex?: Neuropsychology/Neuropsychological correlates of physiologic markers of cognitive decline/Dementia
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background Obstructive sleep apnea (OSA) is a risk factor for cognitive decline, but the effect of sex on this association is unknown. This study aims…”
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REM sleep is associated with the integrity of the cholinergic basal forebrain in aMCI participants
Published in Alzheimer's & dementia (01-12-2022)“…Background The basal forebrain cholinergic system (BFCS) degenerates in Alzheimer’s disease (AD) before the onset of dementia. Interestingly, rapid‐eye…”
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Associations between REM‐sleep EEG spectral power, the cholinergic basal forebrain volume and episodic memory in ageing
Published in Alzheimer's & dementia (01-12-2021)“…Background Our research team has demonstrated that quantitative electroencephalography (qEEG) slowing during rapid‐eye movement (REM) sleep is a more powerful…”
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Age‐stratified, sex‐specific differences in cognitive performance based on risk of obstructive sleep apnea and systemic inflammation: A cross‐sectional analysis of the Canadian Longitudinal Study of Aging
Published in Alzheimer's & dementia (01-12-2021)“…Background Growing evidence supports associations between cognitive impairment and obstructive sleep apnea (OSA). Our study aimed at determining the age and…”
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Differential impact of obstructive sleep apnea on hippocampal structure in late middle‐aged and older women and men
Published in Alzheimer's & dementia (01-12-2021)“…Background Recent studies have suggested that obstructive sleep apnea (OSA) could be a modifiable risk factor for dementia. Consequently, efforts have been…”
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