Search Results - "Martindale, L."

LincRNA-p21 Suppresses Target mRNA Translation by Yoon, Je-Hyun, Abdelmohsen, Kotb, Srikantan, Subramanya, Yang, Xiaoling, Martindale, Jennifer L., De, Supriyo, Huarte, Maite, Zhan, Ming, Becker, Kevin G., Gorospe, Myriam

“…Mammalian long intergenic noncoding RNAs (lincRNAs) are best known for modulating transcription. Here we report a posttranscriptional function for lincRNA-p21…”
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Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1 by Abdelmohsen, Kotb, Panda, Amaresh C., Munk, Rachel, Grammatikakis, Ioannis, Dudekula, Dawood B., De, Supriyo, Kim, Jiyoung, Noh, Ji Heon, Kim, Kyoung Mi, Martindale, Jennifer L., Gorospe, Myriam

“…HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to…”
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Identification of senescent cell surface targetable protein DPP4 by Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L, Yang, Xiaoling, Indig, Fred E, Basu, Sandip K, Ohnuma, Kei, Morimoto, Chikao, Johnson, Peter F, Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam

“…Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass…”
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Diagnosing Acute Heart Failure in the Emergency Department: A Systematic Review and Meta‐analysis by Martindale, Jennifer L., Wakai, Abel, Collins, Sean P., Levy, Phillip D., Diercks, Deborah, Hiestand, Brian C., Fermann, Gregory J., deSouza, Ian, Sinert, Richard, Carpenter, Christopher

“…Background Acute heart failure (AHF) is one of the most common diagnoses assigned to emergency department (ED) patients who are hospitalized. Despite its high…”
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HuR recruits let-7/RISC to repress c-Myc expression by Kim, Hyeon Ho, Kuwano, Yuki, Srikantan, Subramanya, Lee, Eun Kyung, Martindale, Jennifer L, Gorospe, Myriam

“…RNA-binding proteins (RBPs) and microRNAs (miRNAs) are potent post-transcriptional regulators of gene expression. Here, we show that the RBP HuR reduced c-Myc…”
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Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination by Yoon, Je-Hyun, Abdelmohsen, Kotb, Kim, Jiyoung, Yang, Xiaoling, Martindale, Jennifer L., Tominaga-Yamanaka, Kumiko, White, Elizabeth J., Orjalo, Arturo V., Rinn, John L., Kreft, Stefan G., Wilson, Gerald M., Gorospe, Myriam

“…Although mammalian long non-coding (lnc)RNAs are best known for modulating transcription, their post-transcriptional influence on mRNA splicing, stability and…”
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Cellular response to oxidative stress: Signaling for suicide and survival by Martindale, Jennifer L., Holbrook, Nikki J.

“…Reactive oxygen species (ROS), whether produced endogenously as a consequence of normal cell functions or derived from external sources, pose a constant threat…”
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Resolution of Sonographic B-Lines as a Measure of Pulmonary Decongestion in Acute Heart Failure by Martindale, Jennifer L., MD

“…Abstract Objective non-invasive measures of dyspnea in patients with acute heart failure are lacking. In this review we describe lung ultrasound as a tool to…”
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Are All Endoscopy-Related Musculoskeletal Injuries Created Equal? Results of a National Gender-Based Survey by Pawa, Swati, Banerjee, Promila, Kothari, Shivangi, D'Souza, Sharlene L., Martindale, Sarah L., Gaidos, Jill K. J., Oxentenko, Amy S., Burke, Carol A.

“…Endoscopy-related injury (ERI) is common in gastroenterologists (GI). The study aim was to assess the prevalence of self-reported ERI, patterns of injury, and…”
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Considerations for the assessment of blast exposure in service members and veterans by Rowland, Jared A, Martindale, Sarah L

“…Blast exposure is an increasingly present occupational hazard for military service members, particularly in modern warfare scenarios. The study of blast…”
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Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs by Lal, Ashish, Mazan-Mamczarz, Krystyna, Kawai, Tomoko, Yang, Xiaoling, Martindale, Jennifer L, Gorospe, Myriam

“…RNA‐binding proteins HuR and AUF1 bind to many common AU‐rich target mRNAs and exert opposing influence on target mRNA stability, but the functional…”
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miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor γ Expression by Lee, Eun Kyung, Lee, Mi Jeong, Abdelmohsen, Kotb, Kim, Wook, Kim, Mihee M., Srikantan, Subramanya, Martindale, Jennifer L., Hutchison, Emmette R., Kim, Hyeon Ho, Marasa, Bernard S., Selimyan, Roza, Egan, Josephine M., Smith, Steven R., Fried, Susan K., Gorospe, Myriam

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer by Li, Xiao Ling, Subramanian, Murugan, Jones, Matthew F., Chaudhary, Ritu, Singh, Deepak K., Zong, Xinying, Gryder, Berkley, Sindri, Sivasish, Mo, Min, Schetter, Aaron, Wen, Xinyu, Parvathaneni, Swetha, Kazandjian, Dickran, Jenkins, Lisa M., Tang, Wei, Elloumi, Fathi, Martindale, Jennifer L., Huarte, Maite, Zhu, Yuelin, Robles, Ana I., Frier, Susan M., Rigo, Frank, Cam, Maggie, Ambs, Stefan, Sharma, Sudha, Harris, Curtis C., Dasso, Mary, Prasanth, Kannanganattu V., Lal, Ashish

“…Basal p53 levels are tightly suppressed under normal conditions. Disrupting this regulation results in elevated p53 levels to induce cell cycle arrest,…”
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A dual-activity topoisomerase complex regulates mRNA translation and turnover by Su, Shuaikun, Xue, Yutong, Sharov, Alexei, Zhang, Yongqing, Lee, Seung Kyu, Martindale, Jennifer L, Li, Wen, Ku, Wai Lim, Zhao, Keji, De, Supriyo, Shen, Weiping, Sen, Payel, Gorospe, Myriam, Xu, Dongyi, Wang, Weidong

“…Abstract Topoisomerase 3β (TOP3B) and TDRD3 form a dual-activity topoisomerase complex that interacts with FMRP and can change the topology of both DNA and…”
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LncRNA OIP5-AS1-directed miR-7 degradation promotes MYMX production during human myogenesis by Yang, Jen-Hao, Chang, Ming-Wen, Tsitsipatis, Dimitrios, Yang, Xiaoling, Martindale, Jennifer L, Munk, Rachel, Cheng, Aiwu, Izydore, Elizabeth, Pandey, Poonam R, Piao, Yulan, Mazan-Mamczarz, Krystyna, De, Supriyo, Abdelmohsen, Kotb, Gorospe, Myriam

“…Abstract Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) modulate gene expression programs in physiology and disease. Here, we report a noncoding RNA…”
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PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity by Yoon, Je-Hyun, De, Supriyo, Srikantan, Subramanya, Abdelmohsen, Kotb, Grammatikakis, Ioannis, Kim, Jiyoung, Kim, Kyoung Mi, Noh, Ji Heon, White, Elizabeth J. F., Martindale, Jennifer L., Yang, Xiaoling, Kang, Min-Ju, Wood, William H., Hooten, Nicole Noren, Evans, Michele K., Becker, Kevin G., Tripathi, Vidisha, Prasanth, Kannanganattu V., Wilson, Gerald M., Tuschl, Thomas, Ingolia, Nicholas T., Hafner, Markus, Gorospe, Myriam

“…Post-transcriptional gene regulation is robustly regulated by RNA-binding proteins (RBPs). Here we describe the collection of RNAs regulated by AUF1…”
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The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells by Chen, Jing, Martindale, Jennifer L., Cramer, Carole, Gorospe, Myriam, Atasoy, Ulus, Drew, Paul D., Yu, Shiguang

“…In both multiple sclerosis and experimental autoimmune encephalomyelitis (EAE), the C-C chemokine receptor 6 (CCR6) is critical for pathogenic T helper 17…”
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A BDNF-TrkB autocrine loop enhances senescent cell viability by Anerillas, Carlos, Herman, Allison B., Munk, Rachel, Garrido, Amanda, Lam, Kwan-Wood Gabriel, Payea, Matthew J., Rossi, Martina, Tsitsipatis, Dimitrios, Martindale, Jennifer L., Piao, Yulan, Mazan-Mamczarz, Krystyna, Fan, Jinshui, Cui, Chang-Yi, De, Supriyo, Abdelmohsen, Kotb, de Cabo, Rafael, Gorospe, Myriam

“…Cellular senescence is characterized by cell cycle arrest, resistance to apoptosis, and a senescence-associated secretory phenotype (SASP) whereby cells…”
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Competitive Regulation of Nucleolin Expression by HuR and miR-494 by Tominaga, Kumiko, Srikantan, Subramanya, Lee, Eun Kyung, Subaran, Sarah S., Martindale, Jennifer L., Abdelmohsen, Kotb, Gorospe, Myriam

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increased PTCHD4 expression via m6A modification of PTCHD4 mRNA promotes senescent cell survival by Rossi, Martina, Banskota, Nirad, Shin, Chang Hoon, Anerillas, Carlos, Tsitsipatis, Dimitrios, Yang, Jen-Hao, Munk, Rachel, Martindale, Jennifer L, Yang, Xiaoling, Piao, Yulan, Mazan-Mamczarz, Krystyna, Fan, Jinshui, Lehrmann, Elin, Lam, Kwan-Wood Gabriel, De, Supriyo, Abdelmohsen, Kotb, Gorospe, Myriam

“…RNA modifications, including N6-methyladenosine (m6A), critically modulate protein expression programs in a range of cellular processes. Although the…”
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