Search Results - "Martina RUDGALVYTĖ"

Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP(+) Toxicity-Induced Parkinson's Disease Models by Lehtonen, Šárka, Jaronen, Merja, Vehviläinen, Piia, Lakso, Merja, Rudgalvyte, Martina, Keksa-Goldsteine, Velta, Wong, Garry, Courtney, Michael J, Koistinaho, Jari, Goldsteins, Gundars

“…Protein misfolding occurs in neurodegenerative diseases, including Parkinson's disease (PD). In endoplasmic reticulum (ER), an overload of misfolded proteins,…”
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Implementation of postgenomic technologies for cancer research. Institutional experience by Martina RUDGALVYTĖ, Diana STANČIŪTĖ, Kristina BIELSKIENĖ, Violeta JONUŠIENĖ, Vida KIRVELIENĖ, Kęstutis SUŽIEDĖLIS, Vydmantas ATKOČIUS, Konstantinas Povilas VALUCKAS

“…Advance in molecular biology and the new technologies for biomedical research are being rapidly introduced into the research of complex pathologies worldwide…”
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Chronic MeHg exposure modifies the histone H3K4me3 epigenetic landscape in Caenorhabditis elegans by Rudgalvyte, Martina, Peltonen, Juhani, Lakso, Merja, Wong, Garry

“…Methylmercury (MeHg) is a persistent environmental pollutant that occurs in the food chain, at occupational sites, and via medical procedures. Exposure in…”
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Perspectives on C. elegans models of human Parkinson’s Disease by Rudgalvyte, Martina, Wong, Garry

“…Caenorhabditis elegans is a 1 mm long nematode comprised of 959 cells in the adult hermaphrodite. Through transgenic injection, neurotoxin treatment, or…”
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Dual-Acting Nitric Oxide Donor and Phosphodiesterase Inhibitor TOP-N53 Increases Lifespan and Health Span of Caenorhabditis elegans by Rudgalvyte, Martina, Atzei, Paola, de Brito Francisco, Rita, Naef, Reto, Glauser, Dominique A

“…The quest for extending lifespan and promoting a healthy aging has been a longstanding pursuit in the field of aging research. The control of aging and…”
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RNA-Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans by Rudgalvyte, Martina, Peltonen, Juhani, Lakso, Merja, Nass, Richard, Wong, Garry

“…ABSTRACT Manganese (Mn) is an essential nutrient; nonetheless, excessive amounts can accumulate in brain tissues causing manganism, a severe neurological…”
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Global microRNA Expression Profiling of Caenorhabditis elegans Parkinson's Disease Models by Asikainen, Suvi, Rudgalvyte, Martina, Heikkinen, Liisa, Louhiranta, Kristiina, Lakso, Merja, Wong, Garry, Nass, Richard

“…MicroRNAs (miRNAs) play an important role in human brain development and maintenance. To search for miRNAs that may be involved in the pathogenesis of…”
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Methylmercury exposure increases lipocalin related (lpr) and decreases activated in blocked unfolded protein response (abu) genes and specific miRNAs in Caenorhabditis elegans by Rudgalvyte, Martina, VanDuyn, Natalia, Aarnio, Vuokko, Heikkinen, Liisa, Peltonen, Juhani, Lakso, Merja, Nass, Richard, Wong, Garry

“…•Chronic methylmercury exposure increases oxidative stress and endoplasmic reticulum stress gene expression.•Chronic methylmercury exposure increases lpr and…”
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Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans by Aarnio, Vuokko, Storvik, Markus, Lehtonen, Marko, Asikainen, Suvi, Reisner, Kaja, Callaway, James, Rudgalvyte, Martina, Lakso, Merja, Wong, Garry

“…The aryl hydrocarbon receptor (AHR) is a eukaryotic transcription factor that plays an essential role in neuronal, immune, vascular, hepatic and hematopoietic…”
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Perspectives on Caenorhabditis elegans models of human Parkinson’s Disease by Rudgalvyte, Martina, Wong, Garry

“…Caenorhabditis elegans is a 1 mm long nematode comprised of 959 cells in the adult hermaphrodite. Through transgenic injection, neurotoxin treatment, or…”
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