Search Results - "Martina, Bago Pilátová"

Development of novel parameter for monitoring of malignant melanoma progression by Špaková, Ivana, Rabajdová, Miroslava, Dubayová, Katarína, Nagyová, Vladimíra, Pilátová, Martina Bago, Mareková, Mária

“…Increasing HIFs in malignant melanoma, the highly aggressive skin tumour, results in the stimulation of invasiveness. Increased HIF-1α fallouts in inhibition…”
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Synthesis and anticancer profile of novel FTY720 analogues with azobenzene frameworks by Fazekašová, Simona, Gonda, Jozef, Martinková, Miroslava, Pilátová, Martina Bago, Majirská, Monika, Turčanová, Veronika, Jáger, Dávid

“…A short synthetic route towards novel cytotoxic FTY720 analogues bearing a variously substituted azobenzene unit was developed. The target compounds were…”
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Targeting hematological malignancies with isoxazole derivatives by Majirská, Monika, Pilátová, Martina Bago, Kudličková, Zuzana, Vojtek, Martin, Diniz, Carmen

“…[Display omitted] •Hematological malignancies comprise 1.2 million new cases annually worldwide.•Current treatment options are limited by cancer cell…”
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A simple approach to novel 1,3-diamino-1,3-dideoxydihydrosphingosines by Fábian, Martin, Vargová, Kristína, Pončáková, Tatiana, Martinková, Miroslava, Pilátová, Martina Bago, Kuchár, Juraj, Litecká, Miroslava

“…[Display omitted] A short and flexible construction of novel dihydrosphingosine-type analogues has been accomplished. The pivotal step of this approach was a…”
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An efficient synthesis and cytotoxic profile of D-ribo-phytosphingosine and its analogues by Želinská, Milica, Vargová, Kristína, Pončáková, Tatiana, Pilátová, Martina Bago, Martinková, Miroslava, Majirská, Monika, Kuchár, Juraj, Litecká, Miroslava, Prchal, Lukáš

“…In this paper we describe the efficient synthesis of d-ribo-phytosphingosine and its analogues commencing from the easily available l-erythrose chiron, which…”
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A ‘Chiron’ approach to novel phytosphingosine mimetics based on a cascade [3,3]-sigmatropic rearrangement by Raschmanová, Jana Špaková, Fazekašová, Simona, Martinková, Miroslava, Fábian, Martin, Pilátová, Martina Bago, Cvačka, Josef, Kofroňová, Edita, Mezencev, Roman

“…Straightforward access to enantiomerically pure 3,4-diamino-3,4-dideoxyphytosphingosines, as novel analogues of natural d-ribo-phytosphingosine was…”
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A straightforward approach toward cytotoxic pyrrolidine alkaloids: Novel analogues of natural broussonetines by Fábianová, Dominika, Pončáková, Tatiana, Martinková, Miroslava, Fábian, Martin, Fabišíková, Milica, Pilátová, Martina Bago, Macejová, Alexandra, Kuchár, Juraj, Jáger, Dávid

“…Straightforward access to a series of the cytotoxic sphingolipid-derived alkaloids possessing a pyrrolidine unit and a long hydrophobic side chain was…”
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Divergent access to a novel 3,4-diaminophytosphingosine-like ceramide via sequential Overman rearrangement by Fábian, Martin, Novotná, Michaela, Raschmanová, Jana Špaková, Vargová, Kristína, Martinková, Miroslava, Pilátová, Martina Bago, Kešeľáková, Alexandra

“…A straightforward approach to a novel phytosphingosine-like ceramide has been accomplished. The cornerstone features of this divergent synthesis are a cascade…”
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Synthesis and in vitro antiproliferative profile of novel isomeric aza-analogues of natural jaspine B by Novotná, Michaela, Raschmanová, Jana Špaková, Martinková, Miroslava, Pilátová, Martina Bago, Kuchár, Juraj, Litecká, Miroslava, Jáger, Dávid

“…A successful strategy for the construction of novel isomeric aza-analogues 13. HCl and 14. HCl of natural jaspine B was developed by constructing a vicinal…”
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Stereoselective synthesis and anticancer profile of C-alkyl pyrrolidine-diols with a sphingoid base-like backbone by Pončáková, Tatiana, Fábian, Martin, Martinková, Miroslava, Novotná, Michaela, Fabišíková, Milica, Tvrdoňová, Monika, Pilátová, Martina Bago, Nosálová, Natália, Kuchár, Juraj, Jáger, Dávid, Litecká, Miroslava

“…The chiron approach to pyrrolidine-containing isophytosphingosine base-like compounds 21.HCl-23.HCl was developed from the known d-glucofuranose template. The…”
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Spectral, structural, and pharmacological studies of perillaldehyde and myrtenal based benzohydrazides by Garberová, Monika, Potočňák, Ivan, Tvrdoňová, Monika, Bago-Pilátová, Martina, Bekešová, Slávka, Kudličková, Zuzana, Samoľová, Erika, Kešeľáková, Alexandra, Elečko, Ján, Vilková, Mária

“…•Synthesis of new perillaldehyde and myrtenal based benzohydrazides.•The NMR experiments in solution confirmed the presence of two conformers as well as H-bond…”
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Homospisulosine induced apoptosis in cervical carcinoma cells is associated with phosphorylation of Bcl-2 and up-regulation of p27/Kip1 by Pilatova, Martina Bago, Nosalova, Natalia, Ockajakova, Gabriela, Kello, Martin, Kotorova, Klaudia, Takac, Peter, Petik, Peter, Bohus, Peter, Stankova, Kvetoslava, Martinkova, Miroslava, Mezencev, Roman

“…Spisulosine (1-deoxysphinganine) is a sphingoid amino alcohol isolated from the sea clams that showed potent antiproliferative activity against a broad…”
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Derivatives Incorporating Acridine, Pyrrole, and Thiazolidine Rings as Promising Antitumor Agents by Garberová, Monika, Potočňák, Ivan, Tvrdoňová, Monika, Majirská, Monika, Bago-Pilátová, Martina, Bekešová, Slávka, Kováč, Andrej, Takáč, Peter, Khiratkar, Krutika, Kudličková, Zuzana, Elečko, Ján, Vilková, Mária

“…Derivatives combining acridine, pyrrole, and thiazolidine rings have emerged as promising candidates in the field of antitumor drug discovery. This paper aims…”
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Spirocyclization reactions and antiproliferative activity of indole phytoalexins 1-methoxybrassinin and its 1-substituted derivatives by Budovská, Mariana, Pilátová, Martina Bago, Tischlerová, Viera, Mojžiš, Ján

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Ceramides and their roles in programmed cell death by Pilátová, Martina Bago, Solárová, Zuzana, Mezencev, Roman, Solár, Peter

“…Programmed cell death plays a crucial role in maintaining the homeostasis and integrity of multicellular organisms, and its dysregulation contributes to the…”
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An approach to pyrrolidine-containing sphingomimetics based on l-tartaric acid chiron by Špaková Raschmanová, Jana, Fábian, Martin, Sudzina, Adam, Martinková, Miroslava, Bago Pilátová, Martina, Cvačka, Josef, Kofroňová, Edita, Mezencev, Roman

“…A short synthetic approach to constructing pyrrolidine-containing sphingolipid-like derivatives has been accomplished. The cornerstone feature of the synthesis…”
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Straightforward access to novel cytotoxic phytosphingosine-like aminotriols from l-erythrose chiron by Vargová, Kristína, Martinková, Miroslava, Raschmanová, Jana Špaková, Pilátová, Martina Bago, Kešeľáková, Alexandra, Jáger, Dávid

“…A divergent approach to a small library of long-chain 6-amino-1,4,5-triols as novel phytosphingosine-type entities, together with their preliminary cytotoxic…”
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The first synthesis of natural alkaloid capparine A by Očenášová, Lucia, Budovská, Mariana, Očenáš, Peter, Tomášková, Nataša, Pilátová, Martina Bago, Mojžiš, Ján

“…Substances containing a spirooxindole framework display important biological activities. Natural alkaloid capparine A [(S)-(−)-1] has an anti-inflammatory…”
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Synthesis and in vitro anticancer activity of penaresidin-related stereoisomeric analogues by Raschmanová, Jana Špaková, Martinková, Miroslava, Pilátová, Martina Bago, Nosálová, Natália, Kuchár, Juraj, Bodnár, Gergo

“…A straightforward route to penaresidin-based derivatives with an unsubstituted alkyl side chain was developed. To construct these stereoisomeric…”
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Involvement of Both Extrinsic and Intrinsic Apoptotic Pathways in Tridecylpyrrolidine-Diol Derivative-Induced Apoptosis In Vitro by Nosalova, Natalia, Keselakova, Alexandra, Kello, Martin, Martinkova, Miroslava, Fabianova, Dominika, Pilatova, Martina Bago

“…Despite the decreasing trend in mortality from colorectal cancer, this disease still remains the third most common cause of death from cancer. In the present…”
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