Search Results - "Martin Roop, R."

Uncovering the Hidden Credentials of Brucella Virulence by Roop, 2nd, R Martin, Barton, Ian S, Hopersberger, Dariel, Martin, Daniel W

“…Bacteria in the genus are important human and veterinary pathogens. The abortion and infertility they cause in food animals produce economic hardships in areas…”
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Broad-Host-Range Expression Vectors with Tightly Regulated Promoters and Their Use To Examine the Influence of TraR and TraM Expression on Ti Plasmid Quorum Sensing by Khan, Sharik R, Gaines, Jennifer, Roop, R. Martin II, Farrand, Stephen K

“…Experiments requiring strong repression and precise control of cloned genes can be difficult to conduct because of the relatively high basal level of…”
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That's the Way You Do It by Roop, 2nd, R Martin

“…About one-third of the proteins encoded by the bacterial genomes that have been sequenced to date are proteins of "unknown function." Studies aimed at defining…”
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Just When We Thought We Knew Everything We Needed To Know about Zn Acquisition and Bacterial Pathogenesis by Roop, 2nd, R Martin

“…It is well established that high-affinity zinc importers play essential roles in bacterial virulence, but the studies described by Moreau et al. in this issue…”
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Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing by Campbell, Maxwell, Barton, Ian Scott, Roop, 2nd, R Martin, Chien, Peter

“…Bacteria rely on DNA methylation for restriction-modification systems and epigenetic control of gene expression. Here, we use direct detection of methylated…”
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A novel formamidase is required for riboflavin biosynthesis in invasive bacteria by Yurgel, Svetlana N., Johnson, Skylar A., Rice, Jennifer, Sa, Na, Bailes, Clayton, Baumgartner, John, Pitzer, Josh E., Roop, R. Martin, Roje, Sanja

“…Biosynthesis of riboflavin (RF), the precursor of the redox cofactors FMN and FAD, was thought to be well understood in bacteria, with all the pathway enzymes…”
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Brucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid by Barton, Ian S, Ren, Zhongqing, Cribb, Connor B, Pitzer, Joshua E, Baglivo, Ilaria, Martin, Daniel W, Wang, Xindan, Roop, 2nd, R Martin

“…Histone-like nucleoid structuring (H-NS) and H-NS-like proteins serve as global gene silencers and work with antagonistic transcriptional activators…”
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RNA Chaperone Hfq Independently Coordinates Expression of the VirB Type IV Secretion System and the LuxR-Type Regulator BabR in Brucella abortus 2308 by Caswell, Clayton C, Gaines, Jennifer M, Roop, R. Martin, II

“…The type IV secretion system encoded by the virB operon is required for full virulence of Brucella sp., and the present study links the RNA chaperone Hfq to…”
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Identification of two small regulatory RNAs linked to virulence in Brucella abortus 2308 by Caswell, Clayton C., Gaines, Jennifer M., Ciborowski, Pawel, Smith, Derek, Borchers, Christoph H., Roux, Christelle M., Sayood, Khalid, Dunman, Paul M., Roop II, R. Martin

“…Summary Hfq is an RNA‐binding protein that functions in post‐transcriptional gene regulation by mediating interactions between mRNAs and small regulatory RNAs…”
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Editorial: Pathogenomics of the genus Brucella and beyond, volume II by Cloeckaert, Axel, Roop, 2nd, R Martin, Scholz, Holger C, Whatmore, Adrian M, Zygmunt, Michel S

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Transcriptome-Wide Identification of Hfq-Associated RNAs in Brucella suis by Deep Sequencing by Saadeh, Bashir, Caswell, Clayton C, Chao, Yanjie, Berta, Philippe, Wattam, Alice Rebecca, Roop, 2nd, R Martin, O'Callaghan, David

“…Recent breakthroughs in next-generation sequencing technologies have led to the identification of small noncoding RNAs (sRNAs) as a new important class of…”
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Characterizing the transport and utilization of the neurotransmitter GABA in the bacterial pathogen Brucella abortus by Budnick, James A, Sheehan, Lauren M, Benton, Angela H, Pitzer, Joshua E, Kang, Lin, Michalak, Pawel, Roop, R. Martin, Caswell, Clayton C

“…The neurotransmitter gamma-aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the human brain; however, it is becoming more evident…”
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Subversion of Innate Immune Responses by Brucella through the Targeted Degradation of the TLR Signaling Adapter, MAL by Sengupta, Dola, Koblansky, Alicia, Gaines, Jennifer, Brown, Tim, West, A. Phillip, Zhang, Dekai, Nishikawa, Tak, Park, Sung-Gyoo, Roop, R. Martin, II, Ghosh, Sankar

“…Gram-negative bacteria belonging to the Brucella species cause chronic infections that can result in undulant fever, arthritis, and osteomyelitis in humans…”
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Diverse Genetic Regulon of the Virulence-Associated Transcriptional Regulator MucR in Brucella abortus 2308 by Caswell, Clayton C, Elhassanny, Ahmed E M, Planchin, Emilie E, Roux, Christelle M, Weeks-Gorospe, Jenni N, Ficht, Thomas A, Dunman, Paul M, Roop, 2nd, R Martin

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host by Roop, R. Martin II, Gaines, Jennifer M, Anderson, Eric S, Caswell, Clayton C, Martin, Daniel W

“…Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease in humans known as undulant fever. These bacteria do not…”
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Characterization of the Organic Hydroperoxide Resistance System of Brucella abortus 2308 by Caswell, Clayton C, Baumgartner, John E, Martin, Daniel W, Roop, R. Martin

“…The organic hydroperoxide resistance protein Ohr has been identified in numerous bacteria where it functions in the detoxification of organic hydroperoxides,…”
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The Cation Diffusion Facilitator Family Protein EmfA Confers Resistance to Manganese Toxicity in Brucella abortus 2308 and Is an Essential Virulence Determinant in Mice by Johnsrude, Matthew J, Pitzer, Joshua E, Martin, Daniel W, Roop, 2nd, R Martin

“…The gene designated in the 2308 genome encodes an ortholog of the cation diffusion facilitator family protein EmfA which has been linked to resistance to Mn…”
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The Brucella abortus General Stress Response System Regulates Chronic Mammalian Infection and Is Controlled by Phosphorylation and Proteolysis by Kim, Hye-Sook, Caswell, Clayton C., Foreman, Robert, Roop, R. Martin, Crosson, Sean

“…Brucella spp. are adept at establishing a chronic infection in mammals. We demonstrate that core components of the α-proteobacterial general stress response…”
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Manganese Transporter MntH Is a Critical Virulence Determinant for Brucella abortus 2308 in Experimentally Infected Mice by Anderson, Eric S, Paulley, James T, Gaines, Jennifer M, Valderas, Michelle W, Martin, Daniel W, Menscher, Evan, Brown, Timothy D, Burns, Colin S, Roop, R. Martin II

“…The gene designated BAB1_1460 in the Brucella abortus 2308 genome sequence is predicted to encode the manganese transporter MntH. Phenotypic analysis of an…”
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Investigating the roles of the conserved Cu2+-binding residues on Brucella FtrA in producing conformational stability and functionality by Banerjee, Sambuddha, Garrigues, Ryan J., Chanakira, Mina N., Negron-Olivo, Jacob J., Odeh, Yasmene H., Spuches, Anne M., Martin Roop, R., Pitzer, Joshua Edison, Martin, Daniel W., Dasgupta, Saumya

“…Brucella is a zoonotic pathogen requiring iron for its survival and acquires this metal through the expression of several high-affinity uptake systems. Of…”
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