Search Results - "Martin Kello"

Design, Synthesis and Antiproliferative Evaluation of Bis-Indole Derivatives with a Phenyl Linker: Focus on Autophagy by Marianna, Budovska, Radka, Michalkova, Martin, Kello, Janka, Vaskova, Jan, Mojzis

“…This work deals with the study of the synthesis of new bis-indole analogues with a phenyl linker derived from indole phytoalexins. Synthesis of target…”
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Chalcones and Gastrointestinal Cancers: Experimental Evidence by Michalkova, Radka, Kello, Martin, Cizmarikova, Martina, Bardelcikova, Annamaria, Mirossay, Ladislav, Mojzis, Jan

“…Colorectal (CRC) and gastric cancers (GC) are the most common digestive tract cancers with a high incidence rate worldwide. The current treatment including…”
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Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research by Kapinova, Andrea, Stefanicka, Patrik, Kubatka, Peter, Zubor, Pavol, Uramova, Sona, Kello, Martin, Mojzis, Jan, Blahutova, Dana, Qaradakhi, Tawar, Zulli, Anthony, Caprnda, Martin, Danko, Jan, Lasabova, Zora, Busselberg, Dietrich, Kruzliak, Peter

“…Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast cancer cases are of different ‘sporadic’ cell types, thus placing…”
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Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence by Michalkova, Radka, Mirossay, Ladislav, Kello, Martin, Mojzisova, Gabriela, Baloghova, Janette, Podracka, Anna, Mojzis, Jan

“…There is no doubt that significant progress has been made in tumor therapy in the past decades. However, the discovery of new molecules with potential…”
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Indole phytoalexin derivatives induce mitochondrialmediated apoptosis in human colorectal carcinoma cells by Viera Tischlerova Martin Kello Mariana Budovska Jan Mojzis

“…AIM To investigate the mechanism of the antiproliferative effect of synthetic indole phytoalexin derivatives on human colorectal cancer cell lines.METHODS…”
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Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro by Kubatka, Peter, Uramova, Sona, Kello, Martin, Kajo, Karol, Samec, Marek, Jasek, Karin, Vybohova, Desanka, Liskova, Alena, Mojzis, Jan, Adamkov, Marian, Zubor, Pavol, Smejkal, Karel, Svajdlenka, Emil, Solar, Peter, Samuel, Samson Mathews, Zulli, Anthony, Kassayova, Monika, Lasabova, Zora, Kwon, Taeg Kyu, Pec, Martin, Danko, Jan, Büsselberg, Dietrich

“…Naturally-occurring mixtures of phytochemicals present in plant foods are proposed to possess tumor-suppressive activities. In this work, we aimed to evaluate…”
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The Newly Synthetized Chalcone L1 Is Involved in the Cell Growth Inhibition, Induction of Apoptosis and Suppression of Epithelial-to-Mesenchymal Transition of HeLa Cells by Kuruc, Tomas, Kello, Martin, Petrova, Klaudia, Kudlickova, Zuzana, Kubatka, Peter, Mojzis, Jan

“…Over the past decades, natural products have emerged as promising agents with multiple biological activities. Many studies suggest the antioxidant,…”
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Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma by Kubatka, Peter, Uramova, Sona, Kello, Martin, Kajo, Karol, Kruzliak, Peter, Mojzis, Jan, Vybohova, Desanka, Adamkov, Marian, Jasek, Karina, Lasabova, Zora, Zubor, Pavol, Fialova, Silvia, Dokupilova, Svetlana, Solar, Peter, Pec, Martin, Adamicova, Katarina, Danko, Jan, Adamek, Mariusz, Busselberg, Dietrich

“…It is supposed that plant functional foods, rich in phytochemicals, may potentially have preventive effects in carcinogenesis. In this study, the anticancer…”
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Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses by Kubatka, Peter, Kello, Martin, Kajo, Karol, Samec, Marek, Jasek, Karin, Vybohova, Desanka, Uramova, Sona, Liskova, Alena, Sadlonova, Vladimira, Koklesova, Lenka, Murin, Radovan, Adamkov, Marian, Smejkal, Karel, Svajdlenka, Emil, Solar, Peter, Samuel, Samson Mathews, Kassayova, Monika, Kwon, Taeg Kyu, Zubor, Pavol, Pec, Martin, Danko, Jan, Büsselberg, Dietrich, Mojzis, Jan

“…Comprehensive oncology research suggests an important role of phytochemicals or whole plant foods in the modulation of signaling pathways associated with…”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Kubatka, Peter, Kello, Martin, Kajo, Karol, Samec, Marek, Liskova, Alena, Jasek, Karin, Koklesova, Lenka, Kuruc, Tomas, Adamkov, Marian, Smejkal, Karel, Svajdlenka, Emil, Solar, Peter, Pec, Martin, Büsselberg, Dietrich, Sadlonova, Vladimira, Mojzis, Jan

“…Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant foods may beneficially modify carcinogenesis. The aim of this study…”
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Chalcone-Acridine Hybrid Suppresses Melanoma Cell Progression via G2/M Cell Cycle Arrest, DNA Damage, Apoptosis, and Modulation of MAP Kinases Activity by Gazdova, Maria, Michalkova, Radka, Kello, Martin, Vilkova, Maria, Kudlickova, Zuzana, Baloghova, Janette, Mirossay, Ladislav, Mojzis, Jan

“…This study was focused on investigating the antiproliferative effects of chalcone hybrids in melanoma cancer cells. Among seven chalcone hybrids, the…”
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Involvement of Both Extrinsic and Intrinsic Apoptotic Pathways in Tridecylpyrrolidine-Diol Derivative-Induced Apoptosis In Vitro by Nosalova, Natalia, Keselakova, Alexandra, Kello, Martin, Martinkova, Miroslava, Fabianova, Dominika, Pilatova, Martina Bago

“…Despite the decreasing trend in mortality from colorectal cancer, this disease still remains the third most common cause of death from cancer. In the present…”
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Derivatization of Rosmarinic Acid Enhances its in vitro Antitumor, Antimicrobial and Antiprotozoal Properties by Bittner Fialová, Silvia, Kello, Martin, Čoma, Matúš, Slobodníková, Lívia, Drobná, Eva, Holková, Ivana, Garajová, Mária, Mrva, Martin, Zachar, Vlastimil, Lukáč, Miloš

“…On its own, rosmarinic acid possesses multiple biological activities such as anti-inflammatory, antimicrobial, cardioprotective and antitumor properties, and…”
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Programmed Cell Death Alterations Mediated by Synthetic Indole Chalcone Resulted in Cell Cycle Arrest, DNA Damage, Apoptosis and Signaling Pathway Modulations in Breast Cancer Model by Michalkova, Radka, Kello, Martin, Kudlickova, Zuzana, Gazdova, Maria, Mirossay, Ladislav, Mojzisova, Gabriela, Mojzis, Jan

“…Although new chemotherapy significantly increased the survival of breast cancer (BC) patients, the use of these drugs is often associated with serious…”
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Apoptotic Effect of Homobrassinin and Thiazino[6,5-b]indol is Associated with Downregulation of Heat Shock Proteins in Human Ovarian Adenocarcinoma Cells by Solárová, Zuzana, Kello, Martin, Solár, Peter

“…Phytoalexins are substances with antimicrobial properties produced by plants after being attacked by microorganisms, especially phytopathogenic fungi and…”
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Oxidative Stress-Induced DNA Damage and Apoptosis in Clove Buds-Treated MCF-7 Cells by Kello, Martin, Takac, Peter, Kubatka, Peter, Kuruc, Tomas, Petrova, Klaudia, Mojzis, Jan

“…In recent decades, several spices have been studied for their potential in the prevention and treatment of cancer. It is documented that spices have…”
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Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress by Takac, Peter, Kello, Martin, Vilkova, Maria, Vaskova, Janka, Michalkova, Radka, Mojzisova, Gabriela, Mojzis, Jan

“…Chalcones are naturally occurring phytochemicals with diverse biological activities including antioxidant, antiproliferative, and anticancer effects. Some…”
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Mechanochemistry of Chitosan-Coated Zinc Sulfide (ZnS) Nanocrystals for Bio-imaging Applications by Bujňáková, Zdenka, Dutková, Erika, Kello, Martin, Mojžiš, Ján, Baláž, Matej, Baláž, Peter, Shpotyuk, Oleh

“…The ZnS nanocrystals were prepared in chitosan solution (0.1 wt.%) using a wet ultra-fine milling. The obtained suspension was stable and reached high value of…”
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Caffeic Acid Phosphanium Derivatives: Potential Selective Antitumor, Antimicrobial and Antiprotozoal Agents by Lukáč, Miloš, Slobodníková, Lívia, Mrva, Martin, Dušeková, Aneta, Garajová, Mária, Kello, Martin, Šebová, Dominika, Pisárčik, Martin, Kojnok, Marián, Vrták, Andrej, Kurin, Elena, Bittner Fialová, Silvia

“…Caffeic acid (CA) is one of the most abundant natural compounds present in plants and has a broad spectrum of beneficial pharmacological activities. However,…”
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Antimicrobial and Anticancer Application of Silver(I) Dipeptide Complexes by Kuzderová, Gabriela, Rendošová, Michaela, Gyepes, Róbert, Sovová, Simona, Sabolová, Danica, Vilková, Mária, Olejníková, Petra, Bačová, Ivana, Stokič, Simonida, Kello, Martin, Vargová, Zuzana

“…Three silver(I) dipeptide complexes [Ag(GlyGly)] (NO ) (AgGlyGly), [Ag (GlyAla)(NO ) ] (AgGlyAla) and [Ag (HGlyAsp)(NO )] (AgGlyAsp) were prepared,…”
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