Search Results - "Martin‐Ruiz, C. M."

Telomeres as biomarkers for ageing and age-related diseases by von Zglinicki, T, Martin-Ruiz, C M

“…Telomeres in telomerase-negative cells shorten during DNA replication in vitro due to numerous causes including the inability of DNA polymerases to fully copy…”
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Immunohistochemical localisation of nicotinic acetylcholine receptor subunits in human cerebellum by Graham, A, Court, J.A, Martin-Ruiz, C.M, Jaros, E, Perry, R, Volsen, S.G, Bose, S, Evans, N, Ince, P, Kuryatov, A, Lindstrom, J, Gotti, C, Perry, E.K

“…Neuronal nicotinic acetylcholine receptors are members of the ligand-gated ion channel superfamily composed of α and β subunits with specific structural,…”
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Molecular analysis of nicotinic receptor expression in autism by Martin-Ruiz, C.M., Lee, M., Perry, R.H., Baumann, M., Court, J.A., Perry, E.K.

“…Autism is a developmental disorder of unknown aetiopathology and lacking any specific pharmacological therapeutic intervention. Neurotransmitters such as…”
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α4 but Not α3 and α7 Nicotinic Acetylcholine Receptor Subunits Are Lost from the Temporal Cortex in Alzheimer's Disease by Martin‐Ruiz, C. M., Court, J. A., Molnar, E., Lee, M., Gotti, C., Mamalaki, A., Tsouloufis, T., Tzartos, S., Ballard, C., Perry, R. H., Perry, E. K.

“…: Neuronal nicotinic acetylcholine receptors labelled with tritiated agonists are reduced in the cerebral cortex in Alzheimer's disease (AD), but to date it…”
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Cholinergic Activity in Autism: Abnormalities in the Cerebral Cortex and Basal Forebrain by Perry, Elaine K., Lee, Mandy L.W., Martin-Ruiz, Carmen M., Court, Jennifer A., Volsen, Stephen G., Merrit, Jenny, Folly, Elizabeth, Iversen, Portia E., Bauman, Margaret L., Perry, Robert H., Wenk, Gary L.

“…OBJECTIVE: Measures of cholinergic transmitter activity were investigated in patients with autism because of reported neuropathological abnormalities in…”
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Alpha and beta nicotinic acetylcholine receptors subunits and synaptophysin in putamen from Parkinson's disease by Martin-Ruiz, C.M, Piggott, M, Gotti, C, Lindstrom, J, Mendelow, A.D, Siddique, M.S, Perry, R.H, Perry, E.K, Court, J.A

“…It is well established that nicotinic receptors in the mammalian striatum are involved in modulation of the release of several neurotransmitters, including…”
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Short telomere length is associated with impaired cognitive performance in European ancestry cohorts by Hägg, S, Zhan, Y, Karlsson, R, Gerritsen, L, Ploner, A, van der Lee, S J, Broer, L, Deelen, J, Marioni, R E, Wong, A, Lundquist, A, Zhu, G, Hansell, N K, Sillanpää, E, Fedko, I O, Amin, N A, Beekman, M, de Craen, A J M, Degerman, S, Harris, S E, Kan, K-J, Martin-Ruiz, C M, Montgomery, G W, Adolfsson, A N, Reynolds, C A, Samani, N J, Suchiman, H E D, Viljanen, A, von Zglinicki, T, Wright, M J, Hottenga, J-J, Boomsma, D I, Rantanen, T, Kaprio, J A, Nyholt, D R, Martin, N G, Nyberg, L, Adolfsson, R, Kuh, D, Starr, J M, Deary, I J, Slagboom, P E, van Duijn, C M, Codd, V, Pedersen, N L

“…The association between telomere length (TL) dynamics on cognitive performance over the life-course is not well understood. This study meta-analyses…”
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Human brain nicotinic receptors, their distribution and participation in neuropsychiatric disorders by Graham, A J, Martin-Ruiz, C M, Teaktong, T, Ray, M A, Court, J A

“…Mapping of nicotinic acetylcholine receptor (nAChR) subtypes and subunits in human brain is far from complete, however it is clear that multiple subunits are…”
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Nicotinic receptor subtypes in human brain related to aging and dementia by Perry, Elaine K, Martin-Ruiz, Carmen M, Court, Jennifer A

“…Neuronal nicotinic receptors are attracting increasing interest, beyond their role in relation to tobacco use, in the areas of human brain aging and disorders…”
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Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population‐based study by Martin‐Ruiz, Carmen M., Gussekloo, Jacobijn, Heemst, Diana, Zglinicki, Thomas, Westendorp, Rudi G. J.

“…Summary Cross‐sectional studies have repeatedly suggested peripheral blood monocyte telomere length as a biomarker of aging. To test this suggestion in a large…”
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Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts by Bateson, Melissa, Aviv, Abraham, Bendix, Laila, Benetos, Athanase, Ben-Shlomo, Yoav, Bojesen, Stig E, Cooper, Cyrus, Cooper, Rachel, Deary, Ian J, Hägg, Sara, Harris, Sarah E, Kark, Jeremy D, Kronenberg, Florian, Kuh, Diana, Labat, Carlos, Martin-Ruiz, Carmen M, Meyer, Craig, Nordestgaard, Børge G, Penninx, Brenda W J H, Pepper, Gillian V, Révész, Dóra, Said, M Abdullah, Starr, John M, Syddall, Holly, Thomson, William Murray, van der Harst, Pim, Whooley, Mary, von Zglinicki, Thomas, Willeit, Peter, Zhan, Yiqiang, Nettle, Daniel

“…Smoking is associated with shorter leucocyte telomere length (LTL), a biomarker of increased morbidity and reduced longevity. This association is widely…”
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Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia by Martin-Ruiz, Carmen M, Haroutunian, Vahram H, Long, Philip, Young, Allan H, Davis, Kenneth L, Perry, Elaine K, Court, Jennifer A

“…The etiology of dementia that occurs in patients with schizophrenia is not well understood. Nicotinic acetylcholine receptors have been implicated in cognitive…”
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alpha 4 But not alpha 3 and alpha 7 Nicotinic Acetylcholine Receptor Subunits Are Lost from the Temporal Cortex in Alzheimer's Disease by Martin-Ruiz, C M, Court, JA, Molnar, E, Lee, M, Gotti, C, Mamalaki, A, Tsouloufis, T, Tzartos, S, Ballard, C, Perry, R H, Perry, E K

“…Neuronal nicotinic acetylcholine receptors labelled with tritiated agonists are reduced in the cerebral cortex in Alzheimer's disease (AD), but to date it has…”
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Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease by Martin-Ruiz, C M, Court, J A, Molnar, E, Lee, M, Gotti, C, Mamalaki, A, Tsouloufis, T, Tzartos, S, Ballard, C, Perry, R H, Perry, E K

“…Neuronal nicotinic acetylcholine receptors labelled with tritiated agonists are reduced in the cerebral cortex in Alzheimer's disease (AD), but to date it has…”
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Cognitive impairment in first psychotic episodes: The role of cannabis by Boi, S., Sanz-Aranguez, B., Salvador, M.T. González, Labrador, R. Gutierrez, Ruíz, C.M. Martín, Caballero, L., De Arce Cordón, R.

“…IntroductionThe role of cannabis on cognitive impairment in first-episode psychosis (FEP) is becoming more important, with multiple investigations on this…”
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