Search Results - "Martin, Zachary M."

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish by Xie, Yanqi, Kril, Liliia M., Yu, Tianxin, Zhang, Wen, Frasinyuk, Mykhaylo S., Bondarenko, Svitlana P., Kondratyuk, Kostyantyn M., Hausman, Elizabeth, Martin, Zachary M., Wyrebek, Przemyslaw P., Liu, Xifu, Deaciuc, Agripina, Dwoskin, Linda P., Chen, Jing, Zhu, Haining, Zhan, Chang-Guo, Sviripa, Vitaliy M., Blackburn, Jessica, Watt, David S., Liu, Chunming

“…Structure-activity relationships (SAR) in the aurone pharmacophore identified heterocyclic variants of the ( Z )-2-benzylidene-6-hydroxybenzofuran-3(2 H )-one…”
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Efficient synthesis of aurone Mannich bases and evaluation of their antineoplastic activity in PC-3 prostate cancer cells by Popova, Antonina V., Frasinyuk, Mykhaylo S., Bondarenko, Svitlana P., Zhang, Wen, Xie, Yanqi, Martin, Zachary M., Cai, Xianfeng, Fiandalo, Michael V., Mohler, James L., Liu, Chunming, Watt, David S., Sviripa, Vitaliy M.

“…An efficient method for regioselective synthesis of C-7 Mannich bases of 6-hydroxyaurones was accomplished by the N,N -dialkylaminomethylation using aminals…”
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