Search Results - "Martin, Sarah K."

Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer by Martin, Sarah K, Pu, Hong, Penticuff, Justin C, Cao, Zheng, Horbinski, Craig, Kyprianou, Natasha

“…Patients with metastatic castration-resistant prostate cancer (CRPC) frequently develop therapeutic resistance to taxane chemotherapy and antiandrogens…”
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Exploitation of the Androgen Receptor to Overcome Taxane Resistance in Advanced Prostate Cancer by Martin, Sarah K, Kyprianou, Natasha

“…Prostate cancer is a tumor addicted to androgen receptor (AR) signaling, even in its castration resistant state, and recently developed antiandrogen therapies…”
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Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease by Astarita, Giuseppe, Jung, Kwang-Mook, Vasilevko, Vitaly, Dipatrizio, Nicholas V, Martin, Sarah K, Cribbs, David H, Head, Elizabeth, Cotman, Carl W, Piomelli, Daniele

“…The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic approach to identify lipid abnormalities in the brains of subjects with AD…”
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N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy by Martin, Sarah K., Banuelos, Carmen A., Sadar, Marianne D., Kyprianou, Natasha

“…Taxane-based chemotherapy is an effective treatment for castration-resistant-prostate cancer (CRPC) via stabilization of microtubules. Previous studies…”
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Early Jurassic Coleopterans from the Mintaja Insect Locality, Western Australia by MARTIN, Sarah K.

“…Beetles （Coleoptera） are the most common insects recovered from the Lower Jurassic Mintaja insect locality of Western Australia, with over half of the fossils…”
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Gene fusions find an ERG-way to tumor inflammation by Martin, Sarah K., Kyprianou, Natasha

“…Commentary to: ERG oncogene modulates prostaglandin signaling in prostate cancer cells Ahmed A. Mohamed, Shyh-Han Tan, Chen Sun, Syed Shaheduzzaman, Ying Hu,…”
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Cofilin Drives Cell-Invasive and Metastatic Responses to TGF-β in Prostate Cancer by COLLAZO, Joanne, BEIBEI ZHU, LARKIN, Spencer, MARTIN, Sarah K, HONG PU, HORBINSKI, Craig, KOOCHEKPOUR, Shahriar, KYPRIANOU, Natasha

“…Cofilin (CFL) is an F-actin-severing protein required for the cytoskeleton reorganization and filopodia formation, which drives cell migration. CFL binding and…”
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Identifying the powers, players, and emotions associated with REDD+ implementation: The case of Guyana’s LCDS by Cummings, Anthony R., Martin, Sarah K.

“…REDD+ remains a critical tool for dealing with increasing levels of atmospheric carbon dioxide. Like other global-level initiatives, REDD+ has strong…”
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Early Triassic (early Olenekian) life in the interior of East Gondwana: mixed marine–terrestrial biota from the Kockatea Shale, Western Australia by Haig, David W., Martin, Sarah K., Mory, Arthur J., McLoughlin, Stephen, Backhouse, John, Berrell, Rodney W., Kear, Benjamin P., Hall, Russell, Foster, Clinton B., Shi, Guang R., Bevan, Jennifer C.

“…A new terrestrial–marine assemblage from the lower beds of a thin outcrop section of the Kockatea Shale in the northern Perth Basin, Western Australia,…”
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Cytoskeleton targeting value in prostate cancer treatment by Martin, Sarah K, Kamelgarn, Marisa, Kyprianou, Natasha

“…Prostate cancer is a disease that affects hundreds of thousands of men in the United States each year. In the early stages of advanced prostate cancer, the…”
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Emerging biomarkers of prostate cancer (Review) by MARTIN, SARAH K, VAUGHAN, TAYLOR B, ATKINSON, TIMOTHY, ZHU, HAINING, KYPRIANOU, NATASHA

“…Prostate cancer progression involves activation of signaling pathways controlling cell proliferation, apoptosis, anoikis, angiogenesis and metastasis. The…”
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A first record of Cretaceous aphids (Hemiptera, Sternorrhyncha, Aphidomorpha) in Australia, from the Lower Cretaceous Koonwarra Fossil Bed, Victoria by Martin, Sarah K, Skidmore, Luke I, Stilwell, Jeffrey D

“…This paper describes the first species of aphid from the Lower Cretaceous Koonwarra Fossil Bed of the Gippsland Basin, southeastern Victoria, Australia. This…”
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The record of Australian Jurassic plant–arthropod interactions by McLoughlin, Stephen, Martin, Sarah K., Beattie, Robert

“…A survey of Australian Jurassic plant fossil assemblages reveals examples of foliar and wood damage generated by terrestrial arthropods attributed to…”
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Early Ordovician conodonts from Barnicarndy 1 stratigraphic well of the Southern Canning Basin, Western Australia by Zhen, Yong Yi, Allen, Heidi J., Martin, Sarah K.

“…Documented here is the systematic description of conodonts from 10 samples collected within the Nambeet Formation in Barnicarndy 1, a deep stratigraphic…”
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Valanginian–Hauterivian vegetation inferred from palynological successions from the southern Perth Basin, Western Australia by Peyrot, Daniel, Ibilola, Olaoluwa, Martin, Sarah K., Thomas, Charmaine M., Olierook, Hugo K.H., Mory, Arthur J.

“…The stepwise fragmentation of Gondwana had a lasting impact on Southern Hemisphere ecosystems, but its consequences remain difficult to ascertain without…”
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A new Bothriembryon from the Nullarbor Plain, Western Australia, with insights on the age of Bothriembryon praecursor from Kangaroo Well, Northern Territory by Ryan, Helen E., Travouillon, Kenny J., Milne, Lynne A., Martin, Sarah K., Thorn, Kailah M., Whisson, Corey S.

“…Fossil Bothriembryon specimens were recovered from the northwestern edges of the Nullarbor Plain, Western Australia, ∼300 km inland from the current southern…”
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Androgen Receptor Regulation by Microtubule‐targeting Chemotherapeutics in Prostate Cancer by Martin, Sarah K., Kyprianou, Natasha

“…Abstract only Prostate cancer (PCa) is the 2 nd leading cause of cancer related death in N. American males and progression to androgen independence is…”
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Early Cretaceous polar biotas of Victoria, southeastern Australia-an overview of research to date by Poropat, Stephen F., Martin, Sarah K., Tosolini, Anne-Marie P., Wagstaff, Barbara E., Bean, Lynne B., Kear, Benjamin P., Vickers-Rich, Patricia, Rich, Thomas H.

“…Poropat, S.F., Martin, S.K., Tosolini, A.-M.P., Wagstaff, B.E, Bean, L.B., Kear, B.P., Vickers-Rich, P. & Rich, T.H., May 2018. Early Cretaceous polar biotas…”
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Late Artinskian–Early Kungurian (Early Permian) warming and maximum marine flooding in the East Gondwana interior rift, Timor and Western Australia, and comparisons across East Gondwana by Haig, David W., Mory, Arthur J., McCartain, Eujay, Backhouse, John, Håkansson, Eckart, Ernst, Andrej, Nicoll, Robert S., Shi, Guang R., Bevan, Jennifer C., Davydov, Vladimir I., Hunter, Aaron W., Keep, Myra, Martin, Sarah K., Peyrot, Daniel, Kossavaya, Olga, Santos, Zelia Dos

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Abstract 2567: Cabazitaxel chemotherapy targets mitotic kinesins resulting in multi-nucleation of prostate cancer cells: A novel mechanism of cross-resistance with antiandrogens in advanced CRPC by Martin, Sarah K., Pu, Hong, Horbinski, Craig, Cao, Zheng, Kyprianou, Natasha

“…Progression to castration-resistant prostate cancer (CRPC) is characterized by increased androgen receptor (AR) and activated AR signaling despite castrate…”
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