Search Results - "Martin, Richard J."

Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin by Liu, Sucai, PhD, Verma, Mukesh, PhD, Michalec, Lidia, PhD, Liu, Weimin, PhD, Sripada, Anand, PhD, Rollins, Donald, MD, Good, James, MD, Ito, Yoko, PhD, Chu, HongWei, PhD, Gorska, Magdalena M., MD, PhD, Martin, Richard J., MD, Alam, Rafeul, MD, PhD

“…Background Type 2 innate lymphoid cells (ILC2s) represent an important type 2 immune cell. Glucocorticoid regulation of human ILC2s is largely unknown…”
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Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33 by Christianson, Christina A., PhD, Goplen, Nicholas P., MS, Zafar, Iram, MS, Irvin, Chaoyu, MS, Good, James T., MD, Rollins, Donald R., MD, Gorentla, Balachandra, PhD, Liu, Weimin, PhD, Gorska, Magdalena M., MD, PhD, Chu, HongWei, MD, Martin, Richard J., MD, Alam, Rafeul, MD, PhD

“…Background Asthma in a mouse model spontaneously resolves after cessation of allergen exposure. We developed a mouse model in which asthma features persisted…”
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Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment by Durack, Juliana, PhD, Lynch, Susan V., PhD, Nariya, Snehal, BS, Bhakta, Nirav R., MD, PhD, Beigelman, Avraham, MD, Castro, Mario, MD, Dyer, Anne-Marie, MS, Israel, Elliot, MD, Kraft, Monica, MD, Martin, Richard J., MD, Mauger, David T., PhD, Rosenberg, Sharon R., MD, MS, Sharp-King, Tonya, PhD, White, Steven R., MD, Woodruff, Prescott G., MD, MPH, Avila, Pedro C., MD, MPH, Denlinger, Loren C., MD, PhD, Holguin, Fernando, MD, Lazarus, Stephen C., MD, Lugogo, Njira, MD, Moore, Wendy C., MD, Peters, Stephen P., MD, Que, Loretta, MD, Smith, Lewis J., MD, Sorkness, Christine A., PharmD, Wechsler, Michael E., MD, MMSc, Wenzel, Sally E., MD, Boushey, Homer A., MD, Huang, Yvonne J., MD

“…Background Compositional differences in the bronchial bacterial microbiota have been associated with asthma, but it remains unclear whether the findings are…”
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The Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma by GOLEVA, Elena, JACKSON, Leisa P, KIRK HARRIS, J, ROBERTSON, Charles E, RAND SUTHERLAND, E, HALL, Clifton F, GOOD, James T, GELFAND, Erwin W, MARTIN, Richard J, LEUNG, Donald Y. M

“…The role of airway microbiome in corticosteroid response in asthma is unknown. To examine airway microbiome composition in patients with…”
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Airway and serum biochemical correlates of refractory neutrophilic asthma by Alam, Rafeul, MD, PhD, Good, James, MD, Rollins, Donald, MD, Verma, Mukesh, PhD, Chu, HongWei, MD, Pham, Tuyet-Hang, MT, Martin, Richard J., MD

“…Background Despite progress in the diagnosis and management of asthma, many patients have poorly controlled or refractory asthma (RA). The mechanism of this RA…”
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Intermittent Hypoxemia in Preterm Infants by Di Fiore, Juliann M., BS, MacFarlane, Peter M., PhD, Martin, Richard J., MD

“…Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple…”
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The nasal methylome and childhood atopic asthma by Yang, Ivana V., PhD, Pedersen, Brent S., PhD, Liu, Andrew H., MD, O'Connor, George T., MD, Pillai, Dinesh, MD, Kattan, Meyer, MD, Misiak, Rana Tawil, MD, Gruchalla, Rebecca, MD, Szefler, Stanley J., MD, Khurana Hershey, Gurjit K., MD, PhD, Kercsmar, Carolyn, MD, Richards, Adam, PhD, Stevens, Allen D., BA, Kolakowski, Christena A., MS, Makhija, Melanie, MD, Sorkness, Christine A., PharmD, Krouse, Rebecca Z., MS, Visness, Cynthia, PhD, Davidson, Elizabeth J., BA, Hennessy, Corinne E., BS, Martin, Richard J., MD, Togias, Alkis, MD, Busse, William W., MD, Schwartz, David A., MD

“…Background Given the strong environmental influence on both epigenetic marks and allergic asthma in children, the epigenetic alterations in respiratory…”
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A brief review on the mode of action of antinematodal drugs by Abongwa, Melanie, Martin, Richard J., Robertson, Alan P.

“…Anthelmintics are some of the most widely used drugs in veterinary medicine. Here we review the mechanism of action of these compounds on nematode parasites…”
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Optimal identification of human conventional and nonconventional (CRTH2–IL7Rα–) ILC2s using additional surface markers by Liu, Sucai, Sirohi, Kapil, Verma, Mukesh, McKay, Jerome, Michalec, Lidia, Sripada, Anand, Danhorn, Tomas, Rollins, Donald, Good, James, Gorska, Magdalena M., Martin, Richard J., Alam, Rafeul

“…Human type 2 innate lymphoid cells (ILC2s) are identified by coupled detection of CRTH2 and IL7Rα on lineage negative (Lin–) cells. Type 2 cytokine production…”
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Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma by Huang, Yvonne J., MD, Nelson, Craig E., PhD, Brodie, Eoin L., PhD, DeSantis, Todd Z., MS, Baek, Marshall S., BS, Liu, Jane, MS, Woyke, Tanja, PhD, Allgaier, Martin, PhD, Bristow, Jim, MD, Wiener-Kronish, Jeanine P., MD, Sutherland, E. Rand, MD, MPH, King, Tonya S., PhD, Icitovic, Nikolina, MAS, Martin, Richard J., MD, Calhoun, William J., MD, Castro, Mario, MD, Denlinger, Loren C., MD, PhD, DiMango, Emily, MD, Kraft, Monica, MD, Peters, Stephen P., MD, PhD, Wasserman, Stephen I., MD, Wechsler, Michael E., MD, Boushey, Homer A., MD, Lynch, Susan V., PhD

“…Background Improvement in lung function after macrolide antibiotic therapy has been attributed to reduction in bronchial infection by specific bacteria…”
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Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics by Nixon, Samantha A., Welz, Claudia, Woods, Debra J., Costa-Junior, Livio, Zamanian, Mostafa, Martin, Richard J.

“…Control of helminth parasites is a key challenge for human and veterinary medicine. In the absence of effective vaccines and adequate sanitation, prophylaxis…”
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Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions by Kotze, Andrew C., Hunt, Peter W., Skuce, Philip, von Samson-Himmelstjerna, Georg, Martin, Richard J., Sager, Heinz, Krücken, Jürgen, Hodgkinson, Jane, Lespine, Anne, Jex, Aaron R., Gilleard, John S., Beech, Robin N., Wolstenholme, Adrian J., Demeler, Janina, Robertson, Alan P., Charvet, Claude L., Neveu, Cedric, Kaminsky, Ronald, Rufener, Lucien, Alberich, Melanie, Menez, Cecile, Prichard, Roger K.

“…•We report on the Consortium for Anthelmintic Resistance and Susceptibility 2013 meeting.•Recent advances in the identification of markers for anthelmintic…”
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Refractory neutrophilic asthma and ciliary genes by Guntur, Vamsi P., Manka, Laurie A., Moore, Camille M., Wynn, Elizabeth, Vladar, Eszter K., Alam, Rafeul, Pham, Tuyet-Hang, Fingerlin, Tasha E., Martin, Richard J.

“…Refractory asthma (RA) remains poorly controlled, resulting in high health care utilization despite guideline-based therapies. Patients with RA manifest higher…”
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A Higher Incidence of Intermittent Hypoxemic Episodes Is Associated with Severe Retinopathy of Prematurity by Di Fiore, Juliann M., BSEE, Bloom, Jeffrey N., MD, Orge, Faruk, MD, Schutt, Alison, MD, Schluchter, Mark, PhD, Cheruvu, Vinay K., MSc, MS, Walsh, Michele, MD, Finer, Neil, MD, Martin, Richard J., MD

“…Objective Retinopathy of prematurity (ROP), a vasoproliferative disorder of the retina in preterm infants, is associated with multiple factors, including…”
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Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel by Kashyap, Sudhanva S, Verma, Saurabh, Voronin, Denis, Lustigman, Sara, Kulke, Daniel, Robertson, Alan P, Martin, Richard J

“…Filariae are parasitic nematodes that are transmitted to their definitive host as third-stage larvae by arthropod vectors like mosquitoes. Filariae cause…”
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Low Oxygen Saturation Target Range is Associated with Increased Incidence of Intermittent Hypoxemia by Di Fiore, Juliann M., BSEE, Walsh, Michele, MD, Wrage, Lisa, MPH, Rich, Wade, RRT, Finer, Neil, MD, Carlo, Waldemar A., MD, Martin, Richard J., MD

“…Objective To test the hypothesis that preterm infants randomized to a low vs high O2 saturation target range have a higher incidence of intermittent hypoxemia…”
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Diethylcarbamazine, TRP channels and Ca2+ signaling in cells of the Ascaris intestine by Williams, Paul D. E., Kashyap, Sudhanva S., McHugh, Mark A., Brewer, Matthew T., Robertson, Alan P., Martin, Richard J.

“…The nematode parasite intestine absorbs nutrients, is involved in innate immunity, can metabolize xenobiotics and as we show here, is also a site of action of…”
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Club cell secretory protein in serum and bronchoalveolar lavage of patients with asthma by Guerra, Stefano, MD, PhD, Vasquez, Monica M., MPH, Spangenberg, Amber, BS, Halonen, Marilyn, PhD, Martin, Richard J., MD

“…The biological functions of CC16 have not been conclusively determined, but in vitro, ex vivo, and animal studies indicate anti-inflammatory, immunomodulatory,…”
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Proteomic analysis of adult Ascaris suum fluid compartments and secretory products by Chehayeb, James F, Robertson, Alan P, Martin, Richard J, Geary, Timothy G

“…Strategies employed by parasites to establish infections are poorly understood. The host-parasite interface is maintained through a molecular dialog that,…”
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Asthma and atypical bacterial infection by Sutherland, E Rand, Martin, Richard J

“…A growing body of basic and clinical science implicates the atypical bacterial pathogens Mycoplasma pneumoniae and Chlamydophila (formerly Chlamydia)…”
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