Search Results - "Martin, Renée H."

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke by Broderick, Joseph P, Palesch, Yuko Y, Demchuk, Andrew M, Yeatts, Sharon D, Khatri, Pooja, Hill, Michael D, Jauch, Edward C, Jovin, Tudor G, Yan, Bernard, Silver, Frank L, von Kummer, Rüdiger, Molina, Carlos A, Demaerschalk, Bart M, Budzik, Ronald, Clark, Wayne M, Zaidat, Osama O, Malisch, Tim W, Goyal, Mayank, Schonewille, Wouter J, Mazighi, Mikael, Engelter, Stefan T, Anderson, Craig, Spilker, Judith, Carrozzella, Janice, Ryckborst, Karla J, Janis, L. Scott, Martin, Renée H, Foster, Lydia D, Tomsick, Thomas A

“…In this randomized trial involving patients with acute ischemic stroke, endovascular therapy after the administration of intravenous tissue plasminogen…”
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What Is Missing From My Missing Data Plan? by Yeatts, Sharon D, Martin, Renée H

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Meiotic errors in human oogenesis and spermatogenesis by Martin, Renée H

“…Abstract Chromosome anomalies are extraordinarily common in human gametes, with approximately 21% of oocytes and 9% of spermatozoa abnormal. The types of…”
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Meiotic chromosome abnormalities in human spermatogenesis by Martin, Renée H.

“…The last few years have witnessed an explosion in the information about chromosome abnormalities in human sperm and the meiotic events that predispose to these…”
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Covariate Imbalance and Adjustment for Logistic Regression Analysis of Clinical Trial Data by Ciolino, Jody D., Martin, Renée H., Zhao, Wenle, Jauch, Edward C., Hill, Michael D., Palesch, Yuko Y.

“…In logistic regression analysis for binary clinical trial data, adjusted treatment effect estimates are often not equivalent to unadjusted estimates in the…”
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Abnormal progression through meiosis in men with nonobstructive azoospermia by Sun, Fei, M.D., Ph.D, Turek, Paul, M.D, Greene, Calvin, M.D, Ko, Evelyn, B.Sc, Rademaker, Alfred, Ph.D, Martin, Renée H., Ph.D

“…Objective To study meiotic abnormalities in men with nonobstructive azoospermia. Design Analysis of synaptonemal complex and recombination in testicular…”
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Is there a relationship between sperm chromosome abnormalities and sperm morphology? by Sun, Fei, Ko, Evelyn, Martin, Renée H

“…This review explores the relationship between sperm chromosomal constitution and morphology. With the advent of techniques for obtaining information on the…”
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Intra-individual and inter-individual variations in sperm aneuploidy frequencies in normal men by Tempest, Helen G., Ph.D, Ko, Evelyn, B.Sc, Rademaker, Alfred, Ph.D, Chan, Peter, M.D, Robaire, Bernard, Ph.D, Martin, Renée H., Ph.D

“…Objective To investigate whether there are intra-individual and/or inter-individual variations in sperm aneuploidy frequencies within the normal male…”
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Variation in crossover interference levels on individual chromosomes from human males by Lian, Jie, Yin, Yimeng, Oliver-Bonet, Maria, Liehr, Thomas, Ko, Evelyn, Turek, Paul, Sun, Fei, Martin, Renée H.

“…Crossovers (COs) generated by homologous recombination ensure the proper segregation of chromosomes during meiosis. COs exhibit interference, which leads to…”
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Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data by Moullaali, Tom J, Wang, Xia, Martin, Reneé H, Shipes, Virginia B, Robinson, Thompson G, Chalmers, John, Suarez, Jose I, Qureshi, Adnan I, Palesch, Yuko Y, Anderson, Craig S

“…Uncertainty persists over the effects of blood pressure lowering in acute intracerebral haemorrhage. We aimed to combine individual patient-level data from the…”
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ALIAS (Albumin in Acute Ischemic Stroke) Trials: Analysis of the Combined Data From Parts 1 and 2 by Martin, Renee’ H, Yeatts, Sharon D, Hill, Michael D, Moy, Claudia S, Ginsberg, Myron D, Palesch, Yuko Y

“…BACKGROUND AND PURPOSE—The ALIAS (Albumin in Acute Ischemic Stroke) part 1 and 2 trials evaluated whether 25% human serum albumin improves clinical outcomes…”
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Immunofluorescence analysis of human spermatocytes by Ko, Evelyn, Martin, Renée H

“…New immunofluorescence techniques allow visual identification of human cells in various stages of meiotic prophase. Antibodies to the synaptonemal complex, the…”
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Level of Systolic Blood Pressure Within the Normal Range and Risk of Recurrent Stroke by Ovbiagele, Bruce, Diener, Hans-Christophe, Yusuf, Salim, Martin, Reneé H, Cotton, Daniel, Vinisko, Richard, Donnan, Geoffrey A, Bath, Philip M, PROFESS Investigators, for the

“…CONTEXT Recurrent stroke prevention guidelines suggest that larger reductions in systolic blood pressure (SBP) are positively associated with a greater…”
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Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass: Randomized Controlled Trial by Graham, Eric M, Martin, Reneé H, Buckley, Jason R, Zyblewski, Sinai C, Kavarana, Minoo N, Bradley, Scott M, Alsoufi, Bahaaldin, Mahle, William T, Hassid, Marc, Atz, Andrew M

“…The efficacy of intraoperative corticosteroids to improve outcomes following congenital cardiac operations remains controversial. The purpose of this study was…”
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Discontinuities and unsynapsed regions in meiotic chromosomes have a cis effect on meiotic recombination patterns in normal human males by Sun, Fei, Oliver-Bonet, Maria, Liehr, Thomas, Starke, Heike, Trpkov, Kiril, Ko, Evelyn, Rademaker, Alfred, Martin, Renée H.

“…During meiosis, homologous chromosome pairing is essential for subsequent meiotic recombination (crossover). Discontinuous chromosome regions (gaps) or…”
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Two-stage Bayesian hierarchical modeling for blinded and unblinded safety monitoring in randomized clinical trials by Liu, Junhao, Wick, Jo, Martin, Renee' H, Meinzer, Caitlyn, Roy, Dooti, Gajewski, Byron

“…Monitoring and reporting of drug safety during a clinical trial is essential to its success. More recent attention to drug safety has encouraged statistical…”
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J-shape relation of blood pressure reduction and outcome in acute intracerebral hemorrhage: A pooled analysis of INTERACT2 and ATACH-II individual participant data by Wang, Xia, Di Tanna, Gian Luca, Moullaali, Tom J, Martin, Renee’ H, Shipes, Virginia B, Robinson, Thompson G, Chalmers, John, Suarez, Jose I, Qureshi, Adnan I, Palesch, Yuko Y, Anderson, Craig S

“…Objective: The aim of this study was to better define the shape of association between the degree (“magnitude”) of early (< 1 h) reduction in systolic blood…”
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Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial by Hill, Michael D, Prof, Martin, Renee H, PhD, Mikulis, David, Prof, Wong, John H, MD, Silver, Frank L, Prof, terBrugge, Karel G, Prof, Milot, Geneviève, Prof, Clark, Wayne M, Prof, MacDonald, R Loch, Prof, Kelly, Michael E, MD, Boulton, Melford, MD, Fleetwood, Ian, MD, McDougall, Cameron, Prof, Gunnarsson, Thorsteinn, MD, Chow, Michael, MD, Lum, Cheemun, MD, Dodd, Robert, MD, Poublanc, Julien, MSc, Krings, Timo, Prof, Demchuk, Andrew M, Prof, Goyal, Mayank, Prof, Anderson, Roberta, PhD, Bishop, Julie, MA, Garman, David, PhD, Tymianski, Michael, Prof

“…Summary Background Neuroprotection with NA-1 (Tat-NR2B9c), an inhibitor of postsynaptic density-95 protein, has been shown in a primate model of stroke. We…”
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High-dose albumin treatment for acute ischaemic stroke (ALIAS) part 2: a randomised, double-blind, phase 3, placebo-controlled trial by Ginsberg, Myron D, Dr Prof, Palesch, Yuko Y, Prof, Hill, Michael D, Prof, Martin, Renee H, PhD, Moy, Claudia S, PhD, Barsan, William G, Prof, Waldman, Bonnie D, JD, Tamariz, Diego, MD, Ryckborst, Karla J, RN

“…Summary Background In animal models of ischaemic stroke, 25% albumin reduced brain infarction and improved neurobehavioural outcome. In a pilot clinical trial,…”
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Bayesian hierarchical EMAX model for dose‐response in early phase efficacy clinical trials by Gajewski, Byron J., Meinzer, Caitlyn, Berry, Scott M., Rockswold, Gaylan L., Barsan, William G., Korley, Frederick K., Martin, Renee’ H.

“…A primary goal of a phase II dose‐ranging trial is to identify a correct dose before moving forward to a phase III confirmatory trial. A correct dose is one…”
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