Search Results - "Martin, Olga A"
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Abscopal effects of radiation therapy: A clinical review for the radiobiologist
Published in Cancer letters (01-01-2015)“…Abstract An “abscopal” effect occurs when localized irradiation perturbs the organism as a whole, with consequences that can be either beneficial or…”
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Low dose ionizing radiation effects on the immune system
Published in Environment international (01-04-2021)“…•Immune alterations are present in many ionizing radiation-induced adverse health outcomes.•Low doses of ionizing radiation induce subtle but persistent immune…”
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Radiotherapy for Non-Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues
Published in Clinical cancer research (01-10-2016)“…To study the response of irradiated and out-of-field normal tissues during localized curative intent radiotherapy. Sixteen patients with non-small cell lung…”
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Radiation therapy-induced metastasis: radiobiology and clinical implications
Published in Clinical & experimental metastasis (01-04-2018)“…Radiation therapy is an effective means of achieving local control in a wide range of primary tumours, with the reduction in the size of the tumour(s) thought…”
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Microbeam Radiotherapy-A Novel Therapeutic Approach to Overcome Radioresistance and Enhance Anti-Tumour Response in Melanoma
Published in International journal of molecular sciences (20-07-2021)“…Melanoma is the deadliest type of skin cancer, due to its invasiveness and limited treatment efficacy. The main therapy for primary melanoma and solitary organ…”
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Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer
Published in PloS one (27-11-2023)“…Background Surgery is essential for curative treatment of solid tumors. Evidence from recent retrospective clinical analyses suggests that use of…”
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Cancer Radiotherapy: Understanding the Price of Tumor Eradication
Published in Frontiers in cell and developmental biology (24-04-2020)Get full text
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Mobilization of Viable Tumor Cells Into the Circulation During Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-02-2014)“…Purpose To determine whether radiation therapy (RT) could mobilize viable tumor cells into the circulation of non-small cell lung cancer (NSCLC) patients…”
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Potential strategies to ameliorate risk of radiotherapy-induced second malignant neoplasms
Published in Seminars in cancer biology (01-06-2016)“…Abstract This review is aimed at the issue of radiation-induced second malignant neoplasms (SMN), which has become an important problem with the increasing…”
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Synchrotron X-Ray Radiation-Induced Bystander Effect: An Impact of the Scattered Radiation, Distance From the Irradiated Site and p53 Cell Status
Published in Frontiers in oncology (21-05-2021)“…Synchrotron radiation, especially microbeam radiotherapy (MRT), has a great potential to improve cancer radiotherapy, but non-targeted effects of synchrotron…”
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Non-Targeted Effects of Synchrotron Radiation: Lessons from Experiments at the Australian and European Synchrotrons
Published in Applied sciences (01-02-2022)“…Studies have been conducted at synchrotron facilities in Europe and Australia to explore a variety of applications of synchrotron X-rays in medicine and…”
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p21: A Two-Faced Genome Guardian
Published in Trends in molecular medicine (01-04-2017)“…Upon DNA damage or other stressors, the tumor suppressor p53 is activated, leading to transient expression of the cyclin-dependent kinase inhibitor (CKI) p21…”
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The role of miRNA in the direct and indirect effects of ionizing radiation
Published in Radiation and environmental biophysics (01-11-2011)“…This review focuses on a number of recent studies that have examined changes in microRNA (miRNA) expression profiles in response to ionizing radiation and…”
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Targeted Accumulation of Macrophages Induced by Microbeam Irradiation in a Tissue-Dependent Manner
Published in Biomedicines (22-03-2022)“…Radiation therapy (RT) is a vital component of multimodal cancer treatment, and its immunomodulatory effects are a major focus of current therapeutic…”
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Treatment for non-small-cell lung cancer and circulating tumor cells
Published in Lung cancer management (01-12-2017)“…Surgery is the main curative therapy for patients with localized non-small-cell lung cancer while radiotherapy (RT), alone or with concurrent platinum-based…”
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Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals
Published in Aging (Albany, NY.) (18-06-2011)“…Younger individuals are more prone to develop cancer upon ionizing radiation (IR) exposure. Radiation-induced tumors are associated with inefficient repair of…”
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Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research
Published in Cancer letters (31-12-2012)“…Abstract Formation of γ-H2AX in response to DNA double stranded breaks (DSBs) provides the basis for a sensitive assay of DNA damage in human biopsies. The…”
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Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?
Published in Nature reviews. Clinical oncology (01-01-2017)“…Key Points Distant metastasis remains a frequent cause of death, even after locoregional disease control is achieved using surgery, radiotherapy, and/or…”
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Combining FLASH and spatially fractionated radiation therapy: The best of both worlds
Published in Radiotherapy and oncology (01-10-2022)“…•Advantages and current limitations of FLASH and spatially fractionated radiotherapy (SFRT).•Similarities and differences between FLASH and SFRT.•Devices for…”
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What's Changed in 75 Years of RadRes? – An Australian Perspective on Selected Topics
Published in Radiation research (01-08-2024)“…Several scientific themes are reviewed in the context of the 75-year period relevant to this special platinum issue of Radiation Research. Two criteria have…”
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