Search Results - "Martin, Katherine R."

Increasing global ocean oxygenation and the Ordovician Radiation: Insights from Th/U of carbonates from the Ordovician of western Utah by Marenco, Pedro J., Martin, Katherine R., Marenco, Katherine N., Barber, Donald C.

“…The Cambrian and Ordovician radiations were the most important biodiversification events in the history of animal life, yet they were separated by intervals of…”
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Adaptive evolution of major histocompatibility complex class I immune genes and disease associations in coastal juvenile sea turtles by Martin, Katherine R, Mansfield, Katherine L, Savage, Anna E

“…Characterizing polymorphism at the major histocompatibility complex (MHC) genes is key to understanding the vertebrate immune response to disease. Despite…”
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The evolution of antimicrobial peptides in Chiroptera by Castellanos, Francisco X., Moreno-Santillán, Diana, Hughes, Graham M., Paulat, Nicole S., Sipperly, Nicolette, Brown, Alexis M., Martin, Katherine R., Poterewicz, Gregory M., Lim, Marisa C. W., Russell, Amy L., Moore, Marianne S., Johnson, Matthew G., Corthals, Angelique P., Ray, David A., Dávalos, Liliana M.

“…High viral tolerance coupled with an extraordinary regulation of the immune response makes bats a great model to study host-pathogen evolution. Although many…”
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Genetic variation among sea turtle life stages and species suggests connectivity among ocean basins by Phillips, Katrina F., Martin, Katherine R., Stahelin, Gustavo D., Savage, Anna E., Mansfield, Katherine L.

“…Regional genetic differentiation of mitochondrial lineages occurs in migratory species with natal philopatry such as sea turtles. However, early juvenile…”
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Promoting apoptosis of neutrophils and phagocytosis by macrophages: novel strategies in the resolution of inflammation by Martin, Katherine R, Ohayon, Delphine, Witko-Sarsat, Veronique

“…Acute inflammation is the body's response to infection or injury, characterised by the rapid infiltration of polymorphonuclear neutrophils to the site of…”
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Whole blood transcriptomics reveals granulocyte colony‐stimulating factor as a mediator of cardiopulmonary bypass‐induced systemic inflammatory response syndrome by Martin, Katherine R, Gamell, Cristina, Tai, Tsin Yee, Bonelli, Roberto, Hansen, Jacinta, Tatoulis, James, Alhamdoosh, Monther, Wilson, Nicholas, Wicks, Ian

“…Objectives Systemic inflammatory response syndrome (SIRS) is a frequent complication of cardiopulmonary bypass (CPB). SIRS is associated with significant…”
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CD98 defines a metabolically flexible, proinflammatory subset of low‐density neutrophils in systemic lupus erythematosus by Martin, Katherine R., Day, Jessica A., Hansen, Jacinta A., D'Silva, Damian B., Wong, Huon L., Garnham, Alexandra, Sandow, Jarrod J., Nijagal, Brunda, Wilson, Nicholas, Wicks, Ian P.

“…Background Low‐density neutrophils (LDN) are a distinct subset of neutrophils rarely detected in healthy people but appear in the blood of patients with…”
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Multiple congenital anomalies and adverse developmental outcomes are associated with neonatal intensive care admission and unilateral hearing loss by Horrocks, Lucy M, Kitterick, Pádraig T, Jayasinghe, Dulip S, Willis, Karen R, Martin, Katherine R M, Dixit, Abhijit, Thornton, Sally K

“…To determine congenital and developmental outcomes of children with Unilateral Hearing Loss (UHL) who were admitted to the Neonatal Intensive Care Unit (NICU)…”
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G-CSF – A double edge sword in neutrophil mediated immunity by Martin, Katherine R., Wong, Huon L., Witko-Sarsat, Véronique, Wicks, Ian P.

“…•Granulocyte colony stimulating factor (G-CSF) is a key regulator of neutrophils.•G-CSF contributes to protecting the host against infection.•Conversely, G-CSF…”
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Over-expression of DSCR1 protects against post-ischemic neuronal injury by Brait, Vanessa H, Martin, Katherine R, Corlett, Alicia, Broughton, Brad R S, Kim, Hyun Ah, Thundyil, John, Drummond, Grant R, Arumugam, Thiruma V, Pritchard, Melanie A, Sobey, Christopher G

“…The Down syndrome candidate region 1 (DSCR1) gene is located on human chromosome 21 and its protein is over-expressed in brains of Down syndrome individuals…”
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Proteinase 3: the odd one out that became an autoantigen by Martin, Katherine R., Witko‐Sarsat, Véronique

“…Review on molecular modeling, and biochemical and functional analysis of PR3 functions in vasculitis. Neutrophils are critical in the defense against bacterial…”
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Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis by Deshpande, Devyani, Srivastava, Shashikant, Nuermberger, Eric, Koeuth, Thearith, Martin, Katherine R, Cirrincione, Kayle N, Lee, Pooi S, Gumbo, Tawanda

“…Abstract Background Children are often neglected during early development of antituberculosis agents, and most receive treatment after it is first tested in…”
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Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis by Millet, Arnaud, Martin, Katherine R, Bonnefoy, Francis, Saas, Philippe, Mocek, Julie, Alkan, Manal, Terrier, Benjamin, Kerstein, Anja, Tamassia, Nicola, Satyanarayanan, Senthil Kumaran, Ariel, Amiram, Ribeil, Jean-Antoine, Guillevin, Loïc, Cassatella, Marco A, Mueller, Antje, Thieblemont, Nathalie, Lamprecht, Peter, Mouthon, Luc, Perruche, Sylvain, Witko-Sarsat, Véronique

“…Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis that is associated with granulomatous inflammation and the presence of…”
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G-CSF reshapes the cytosolic PCNA scaffold and modulates glycolysis in neutrophils by Aymonnier, Karen, Bosetta, Enzo, Leborgne, Nathan G F, Ullmer, Audrey, Le Gall, Morgane, De Chiara, Alessia, Salnot, Virginie, Many, Souganya, Scapini, Patrizia, Wicks, Ian, Chatfield, Simon, Martin, Katherine R, Witko-Sarsat, Véronique

“…Cytosolic proliferating cell nuclear antigen (PCNA) is involved in neutrophil survival and function, in which it acts as a scaffold and associates with…”
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Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis by Deshpande, Devyani, Srivastava, Shashikant, Bendet, Paula, Martin, Katherine R, Cirrincione, Kayle N, Lee, Pooi S, Pasipanodya, Jotam G, Dheda, Keertan, Gumbo, Tawanda

“…The modern chemotherapy era started with Fleming's discovery of benzylpenicillin. He demonstrated that benzylpenicillin did not kill In this study, we found…”
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Dysregulation of neutrophil oxidant production and interleukin-1-related cytokines in granulomatosis with polyangiitis by Amsler, Jennifer, Everts-Graber, Judith, Martin, Katherine R, Roccabianca, Arnaud, Lopes, Chloé, Tourneur, Léa, Mocek, Julie, Karras, Alexandre, Naccache, Jean-Marc, Bonnotte, Bernard, Samson, Maxime, Hanslik, Thomas, Puéchal, Xavier, Terrier, Benjamin, Guillevin, Loïc, Néel, Antoine, Mouthon, Luc, Witko-Sarsat, Véronique

“…Neutrophils play a key role in ANCA-associated vasculitis, both as targets of autoimmunity and as facilitators of vascular damage. In granulomatosis with…”
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Invasive Bullfrogs Maintain MHC Polymorphism Including Alleles Associated with Chytrid Fungal Infection by LaFond, Jacob, Martin, Katherine R, Dahn, Hollis, Richmond, Jonathan Q, Murphy, Robert W, Rollinson, Njal, Savage, Anna E

“…Abstract Maintenance of genetic diversity at adaptive loci may facilitate invasions by non-native species by allowing populations to adapt to novel…”
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Minocycline Immunomodulates via Sonic Hedgehog Signaling and Apoptosis and Has Direct Potency Against Drug-Resistant Tuberculosis by Deshpande, Devyani, Pasipanodya, Jotam G, Srivastava, Shashikant, Martin, Katherine R, Athale, Shruti, van Zyl, Johanna, Antiabong, John, Koeuth, Thearith, Lee, Pooi S, Dheda, Keertan, Gumbo, Tawanda

“…We are running out of treatments for multidrug-resistant tuberculosis. Minocycline, an old and safe antibiotic, was highly potent against Mycobacterium…”
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Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance by Everts-Graber, Judith, Martin, Katherine R, Thieblemont, Nathalie, Mocek, Julie, Roccabianca, Arnaud, Chafey, Philippe, Le Gall, Morgane, Tacnet-Delorme, Pascale, Reutelingsperger, Chris P, Naccache, Jean-Marc, Bonnotte, Bernard, Karras, Alexandre, Puéchal, Xavier, Guillevin, Loïc, Terrier, Benjamin, Frachet, Philippe, Perretti, Mauro, Mouthon, Luc, Witko-Sarsat, Véronique

“…Granulomatosis with polyangiitis (GPA) is an autoimmune vasculitis associated with anti-neutrophil-cytoplasmic antibodies (ANCA) against proteinase 3 leading…”
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Once-a-week tigecycline for the treatment of drug-resistant TB by Deshpande, Devyani, Magombedze, Gesham, Srivastava, Shashikant, Bendet, Paula, Lee, Pooi S, Cirrincione, Kayle N, Martin, Katherine R, Dheda, Keertan, Gumbo, Tawanda

“…MDR-TB and XDR-TB have poor outcomes. To examine the efficacy of tigecycline monotherapy in the hollow fibre system model of TB. We performed…”
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