Search Results - "Martin, Geoffrey V"
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Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling
Published in eLife (09-11-2021)“…Checkpoint inhibitor therapy of cancer has led to markedly improved survival of a subset of patients in multiple solid malignant tumor types, yet the factors…”
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Patterns of failure for recurrent head and neck squamous cell carcinoma treated with salvage surgery and postoperative IMRT reirradiation
Published in Clinical and translational radiation oncology (01-01-2024)“…The purpose of this study was to evaluate patterns of locoregional recurrence (LRR) after surgical salvage and adjuvant reirradiation with IMRT for recurrent…”
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The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactin
Published in Molecular biology of the cell (01-05-2015)“…Kv1.3 channels play a pivotal role in the activation and migration of T-lymphocytes. These functions are accompanied by the channels' polarization, which is…”
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Pre‐treatment neutrophil/lymphocyte ratio and platelet/lymphocyte ratio are prognostic of progression in early stage classical Hodgkin lymphoma
Published in British journal of haematology (01-02-2018)“…Summary To determine whether pre‐treatment neutrophil/lymphocyte (NLR) or platelet/lymphocyte ratios (PLR) are predictive for progression in early‐stage…”
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Modulation of T cell activation by localized K+ accumulation at the immunological synapse—A mathematical model
Published in Journal of theoretical biology (07-05-2012)“…The response of T cells to antigens (T cell activation) is marked by an increase in intracellular Ca2+ levels. Voltage-gated and Ca2+-dependent K+ channels…”
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A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden
Published in Nature biomedical engineering (01-04-2021)“…A large proportion of patients with cancer are unresponsive to treatment with immune checkpoint blockade and other immunotherapies. Here, we report a…”
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Comparison of prostate distortion by inflatable and rigid endorectal MRI coils in permanent prostate brachytherapy imaging
Published in Brachytherapy (01-03-2018)“…To study the deformation of the prostate by a rigid reusable endorectal coil and a balloon-type endorectal coil (BTC) during MRI of the prostate in…”
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Lightning and its association with the frequency of headache in migraineurs: an observational cohort study
Published in Cephalalgia (01-04-2013)“…The aim of this article is to determine if lightning is associated with the frequency of headache in migraineurs. Participants fulfilling diagnostic criteria…”
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Permanent prostate brachytherapy postimplant magnetic resonance imaging dosimetry using positive contrast magnetic resonance imaging markers
Published in Brachytherapy (01-07-2017)“…Permanent prostate brachytherapy dosimetry using computed tomography-magnetic resonance imaging (CT-MRI) fusion combines the anatomic detail of MRI with seed…”
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Allergy and Immunotherapy: Are They Related to Migraine Headache?
Published in Headache (01-01-2011)“…(Headache 2011;51:8‐20) Introduction.— Several studies have reported that migraine headaches are more common in patients with allergic rhinitis and that…”
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Permanent prostate brachytherapy pubic arch evaluation with diagnostic magnetic resonance imaging
Published in Brachytherapy (01-07-2017)“…Pubic arch interference (PAI), when it occurs, is often a limiting factor for patients pursuing brachytherapy treatment of prostate cancer. Pre-brachytherapy…”
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Permanent prostate brachytherapy pubic arch evaluation with diagnostic MRI
Published in Brachytherapy (2017)“…Abstract Purpose Pubic arch interference (PAI), when it occurs, is often a limiting factor for patients pursuing brachytherapy treatment of prostate cancer…”
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Automated Prostate Brachytherapy Seed Detection on Post-Implant MRI Using Novel Martin Algorithm
Published in Brachytherapy (01-05-2017)Get full text
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Are We Ready to Replace Post-Implant CT Dosimetry? Permanent Prostate Brachytherapy Post-Implant MRI Dosimetry Using Positive Contrast MRI Markers
Published in Brachytherapy (01-05-2016)Get full text
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The Sh3-Binding Domain of Kv1.3 Channels is Required for their Cortactin-Conveyed Coupling to Actin
Published in Biophysical journal (28-01-2014)Get full text
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Cortactin and the actin cytoskeleton control the lateral membrane mobility of Kv1.3 channels
Published in The FASEB journal (01-04-2013)“…Abstract only The proper Kv1.3 membrane motility is necessary for T cell polarization and activation. The exact mechanisms regulating Kv1.3 membrane movement,…”
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Permanent Prostate Brachytherapy Post-Implant MRI Dosimetry Using Positive Contrast MRI Markers
Published in Brachytherapy (01-01-2017)Get full text
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Permanent prostate brachytherapy postimplant MRI dosimetry using positive contrast MRI markers
Published in Brachytherapy (2017)“…Abstract Purpose Permanent prostate brachytherapy dosimetry using computed tomography-magnetic resonance imaging (CT-MRI) fusion combines the anatomic detail…”
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