Search Results - "Martin, Eric"
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Liver Transplantation for Primary Biliary Cholangitis
Published in Clinics in liver disease (01-11-2022)“…Despite a significant increase in the total number of liver transplants (LTs) performed over the last 3 decades, primary biliary cholangitis (PBC) has become…”
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Timing, Management, and Outcomes of Liver Transplantation in Primary Sclerosing Cholangitis
Published in Seminars in liver disease (01-11-2017)“…Primary sclerosing cholangitis (PSC) is a chronic, immune-mediated cholestatic liver disease that often progresses to secondary biliary cirrhosis and end-stage…”
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All-Assay-Max2 pQSAR: Activity Predictions as Accurate as Four-Concentration IC50s for 8558 Novartis Assays
Published in Journal of chemical information and modeling (28-10-2019)“…Profile-quantitative structure–activity relationship (pQSAR) is a massively multitask, two-step machine learning method with unprecedented scope, accuracy, and…”
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Paradigm Shift in Utilization of Livers from Hepatitis C–Viremic Donors into Hepatitis C Virus–Negative Patients
Published in Clinics in liver disease (01-02-2021)“…Despite record-breaking numbers of liver transplants (LTs) performed in the United States in each of the last 7 years, many patients remain on the wait list as…”
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S4265 Mixed Adenoneuroendocrine Carcinoma of the Stomach: A Case Report
Published in The American journal of gastroenterology (01-10-2023)Get full text
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Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Published in Cell (27-04-2012)“…Tumor maintenance relies on continued activity of driver oncogenes, although their rate-limiting role is highly context dependent. Oncogenic Kras mutation is…”
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Profile-QSAR 2.0: Kinase Virtual Screening Accuracy Comparable to Four-Concentration IC50s for Realistically Novel Compounds
Published in Journal of chemical information and modeling (28-08-2017)“…While conventional random forest regression (RFR) virtual screening models appear to have excellent accuracy on random held-out test sets, they prove lacking…”
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The Four Cs of disaster partnering: communication, cooperation, coordination and collaboration
Published in Disasters (01-10-2016)“…Public, nonprofit and private organisations respond to large‐scale disasters domestically and overseas. Critics of these assistance efforts, as well as those…”
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Collaborative Profile-QSAR: A Natural Platform for Building Collaborative Models among Competing Companies
Published in Journal of chemical information and modeling (26-04-2021)“…Massively multitask bioactivity models that transfer learning between thousands of assays have been shown to work dramatically better than separate models…”
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A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype
Published in Haematologica (Roma) (01-05-2012)“…A phase II trial of dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin and rituximab (DA-EPOCH-R) from the National Cancer…”
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TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers
Published in Nature genetics (01-08-2020)“…Mammalian cells stably maintain high levels of DNA methylation despite expressing both positive (DNMT3A/B) and negative (TET1-3) regulators. Here, we analyzed…”
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A season long investigation of social emotional learning associated with high school basketball participation
Published in Journal of applied sport psychology (02-11-2022)“…This qualitative, longitudinal investigation had three purposes: (1) to investigate social emotional learning (SEL) outcomes athletes reported from…”
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Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells
Published in Stem cell reports (10-11-2015)“…Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes are regulated…”
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On the Choice of Active Site Sequences for Kinase-Ligand Affinity Prediction
Published in Journal of chemical information and modeling (26-09-2022)“…Recent work showed that active site rather than full-protein-sequence information improves predictive performance in kinase-ligand binding affinity prediction…”
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Oxidative pyrolysis of wood chips and of wood pellets in a downdraft continuous fixed bed reactor
Published in Fuel (Guildford) (15-05-2017)“…•A counter-current oxidation zone was stabilized inside a downdraft reactor.•Detailed mass balance including char, permanent gases and tar yields.•The fed air…”
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Biased Diversity for Effective Virtual Screening
Published in Journal of chemical information and modeling (28-09-2020)“…Virtual screening is no longer merely a matter of identifying the subset of compounds from a large collection likely to be active against a particular…”
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How Humans Comply With a (Potentially) Faulty Robot: Effects of Multidimensional Transparency
Published in IEEE transactions on human-machine systems (01-08-2023)“…This article deals with how a human operator follows a request made by a robot in an industrial context. This robot is potentially myopic, i.e., its request…”
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The Human Epigenome Browser at Washington University
Published in Nature methods (01-12-2011)Get full text
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Basic creep behavior of concretes investigation of the physical mechanisms by using acoustic emission
Published in Cement and concrete research (2012)“…The Laboratoire Central des Ponts et Chaussées has launched a research project to study the physical mechanisms related to the basic creep of concrete to…”
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S4060 Symptomatic Jejunal Diverticulosis: A Rare Entity and a Cause of Recurrent Small Bowel Obstruction
Published in The American journal of gastroenterology (01-10-2023)Get full text
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