Search Results - "Martin, Elliot T"
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Oo-site: A dashboard to visualize gene expression during Drosophila oogenesis suggests meiotic entry is regulated post-transcriptionally
Published in Biology open (15-05-2022)“…Determining how stem cell differentiation is controlled has important implications for understanding the etiology of degenerative disease and designing…”
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Ribosomal protein RACK1 enhances translation of poliovirus and other viral IRESs
Published in Virology (New York, N.Y.) (01-06-2020)“…Viruses have evolved strategies to ensure efficient translation using host cell ribosomes and translation factors. In addition to cleaving translation…”
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Journal Article -
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A feedback loop between heterochromatin and the nucleopore complex controls germ-cell-to-oocyte transition during Drosophila oogenesis
Published in Developmental cell (20-11-2023)“…Germ cells differentiate into oocytes that launch the next generation upon fertilization. How the highly specialized oocyte acquires this distinct cell fate is…”
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A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis
Published in Developmental cell (11-04-2022)“…Ribosomal defects perturb stem cell differentiation, and this is the cause of ribosomopathies. How ribosome levels control stem cell differentiation is not…”
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Msl3 promotes germline stem cell differentiation in female Drosophila
Published in Development (Cambridge) (01-01-2022)“…Gamete formation from germline stem cells (GSCs) is essential for sexual reproduction. However, the regulation of GSC differentiation is incompletely…”
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Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa‐Porthos axis in Drosophila
Published in The EMBO journal (14-06-2022)“…Cellular metabolism must adapt to changing demands to enable homeostasis. During immune responses or cancer metastasis, cells leading migration into…”
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Journal Article -
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PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology
Published in Scientific reports (03-03-2017)“…The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with…”
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Post-transcriptional gene regulation regulates germline stem cell to oocyte transition during Drosophila oogenesis
Published in Current topics in developmental biology (2020)“…During oogenesis, several developmental processes must be traversed to ensure effective completion of gametogenesis including, stem cell maintenance and…”
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Journal Article -
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H/ACA snRNP-dependent ribosome biogenesis regulates translation of polyglutamine proteins
Published in Science advances (23-06-2023)“…Stem cells in many systems, including germline stem cells (GSCs), increase ribosome biogenesis and translation during terminal differentiation. Here, we show…”
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Journal Article -
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Translation Control Tunes Drosophila Oogenesis
Published 01-01-2022“…The decision of a stem cell to either self-renew or differentiate is controlled by specific cellular pathways that can act at the level of transcription,…”
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Dissertation