Search Results - "Martin, Dale S."

Persistence of Borrelia burgdorferi in rhesus macaques following antibiotic treatment of disseminated infection by Embers, Monica E, Barthold, Stephen W, Borda, Juan T, Bowers, Lisa, Doyle, Lara, Hodzic, Emir, Jacobs, Mary B, Hasenkampf, Nicole R, Martin, Dale S, Narasimhan, Sukanya, Phillippi-Falkenstein, Kathrine M, Purcell, Jeanette E, Ratterree, Marion S, Philipp, Mario T

“…The persistence of symptoms in Lyme disease patients following antibiotic therapy, and their causes, continue to be a matter of intense controversy. The…”
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Robust B Cell Responses Predict Rapid Resolution of Lyme Disease by Blum, Lisa K, Adamska, Julia Z, Martin, Dale S, Rebman, Alison W, Elliott, Serra E, Cao, Richard R L, Embers, Monica E, Aucott, John N, Soloski, Mark J, Robinson, William H

“…Lyme disease ( infection) is increasingly recognized as a significant source of morbidity worldwide. Here, we show that blood plasmablasts and CD27 memory B…”
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The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype by Caskey, John R, Hasenkampf, Nicole R, Martin, Dale S, Chouljenko, Vladimir N, Subramanian, Ramesh, Cheslock, Mercedes A, Embers, Monica E

“…Recent studies have shown that can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs…”
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Possible role of glial cells in the onset and progression of Lyme neuroborreliosis by Ramesh, Geeta, Borda, Juan T, Gill, Amy, Ribka, Erin P, Morici, Lisa A, Mottram, Peter, Martin, Dale S, Jacobs, Mary B, Didier, Peter J, Philipp, Mario T

“…Lyme neuroborreliosis (LNB) may present as meningitis, cranial neuropathy, acute radiculoneuropathy or, rarely, as encephalomyelitis. We hypothesized that…”
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Correction: Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection by Embers, Monica E, Barthold, Stephen W, Borda, Juan T, Bowers, Lisa, Doyle, Lara, Hodzic, Emir, Jacobs, Mary B, Hasenkampf, Nicole R, Martin, Dale S, Narasimhan, Sukanya, Phillippi-Falkenstein, Kathrine M, Purcell, Jeanette E, Ratterree, Marion S, Philipp, Mario T

“…[This corrects the article on p. e29914 in vol. 7.]…”
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Induction of Plasmodium falciparum Transmission-Blocking Antibodies in Nonhuman Primates by a Combination of DNA and Protein Immunizations by COBAN, Cevayir, PHILIPP, Mario T, PURCELL, Jeanette E, KEISTER, David B, OKULATE, Mobolaji, MARTIN, Dale S, KUMAR, Nirbhay

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A decline in C6 antibody titer occurs in successfully treated patients with culture-confirmed early localized or early disseminated Lyme Borreliosis by Philipp, Mario T, Wormser, Gary P, Marques, Adriana R, Bittker, Susan, Martin, Dale S, Nowakowski, John, Dally, Leonard G

“…C(6), a Borrelia burgdorferi-derived peptide, is used as the antigen in the C(6)-Lyme disease diagnostic test. We assessed retrospectively whether a fourfold…”
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Inflammation in the Pathogenesis of Lyme Neuroborreliosis by Ramesh, Geeta, Didier, Peter J, England, John D, Santana-Gould, Lenay, Doyle-Meyers, Lara A, Martin, Dale S, Jacobs, Mary B, Philipp, Mario T

“…Lyme neuroborreliosis, caused by the spirochete Borrelia burgdorferi , affects both peripheral and central nervous systems. We assessed a causal role for…”
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Comparative functional potency of DNA vaccines encoding Plasmodium falciparum transmission blocking target antigens Pfs48/45 and Pfs25 administered alone or in combination by in vivo electroporation in rhesus macaques by Datta, Dibyadyuti, Bansal, Geetha P., Grasperge, Brooke, Martin, Dale S., Philipp, Mario, Gerloff, Dietlind, Ellefsen, Barry, Hannaman, Drew, Kumar, Nirbhay

“…Antibodies recognizing conformational epitopes in Pfs48/45, an antigen expressed on the surface of Plasmodium falciparum gametes and zygotes, have firmly…”
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Effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in glial and neuronal cells of the central nervous system by Ramesh, Geeta, Martinez, Alejandra N, Martin, Dale S, Philipp, Mario T

“…Lyme neuroborreliosis (LNB), caused by the spirochete Borrelia burgdorferi (Bb), affects both the central and peripheral nervous systems. Previously, we…”
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Borrelia burgdorferi Spirochetes That Harbor Only a Portion of the lp28-1 Plasmid Elicit Antibody Responses Detectable with the C6 Test for Lyme Disease by Embers, Monica E, Wormser, Gary P, Schwartz, Ira, Martin, Dale S, Philipp, Mario T

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C6 Test as an Indicator of Therapy Outcome for Patients with Localized or Disseminated Lyme Borreliosis by PHILIPP, Mario T, MARQUES, Adriana R, FAWCETT, Paul T, DALLY, Leonard G, MARTIN, Dale S

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Evaluation of the C6 Peptide Enzyme-Linked Immunosorbent Assay for Individuals Vaccinated with the Recombinant OspA Vaccine by MARQUES, Adriana R, MARTIN, Dale S, PHILIPP, Mario T

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Correction: Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection by Embers, Monica E., Barthold, Stephen W., Borda, Juan T., Bowers, Lisa, Doyle, Lara, Hodzic, Emir, Jacobs, Mary B., Hasenkampf, Nicole R., Martin, Dale S., Narasimhan, Sukanya, Phillippi-Falkenstein, Kathrine M., Purcell, Jeanette E., Ratterree, Marion S., Philipp, Mario T.

“…There was an error in the Materials and Methods section titled Animals, spirochetal inoculation, animal groups, and antibiotic treatment. (2012) Correction:…”
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Experimental infection of rhesus macaques with Streptococcus pneumoniae: a possible model for vaccine assessment by Philipp, Mario T., Purcell, Jeanette E., Martin, Dale S., Buck, Wayne R., Plauché, Gail B., Ribka, Erin P., DeNoel, Philippe, Hermand, Philippe, Leiva, Lily E., Bagby, Gregory J., Nelson, Steve

“…Background  We explored the possibility of using normal adult rhesus macaques for the preclinical assessment of safety, immunogenicity, and efficacy of newly…”
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Concentration-dependent differential induction of necrosis or apoptosis by HIV-1 lytic peptide 1 by Plymale, Douglas R, Comardelle, Alla M, Fermin, Cesar D, Martin, Dale S, Costin, Joshua M, Norris, Charles H, Burroughs Tencza, Sarah, Mietzner, Timothy A, Montelaro, Ronald C, Garry, Robert F

“…The mechanism by which human immunodeficiency virus type 1 induces depletion of CD4 + T-lymphocytes remains controversial, but may involve cytotoxic viral…”
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Borrelia burgdorferi Spirochetes That Harbor Only a Portion of the lp28-1 Plasmid Elicit Antibody Responses Detectable with the C 6 Test for Lyme Disease by Embers, Monica E., Wormser, Gary P., Schwartz, Ira, Martin, Dale S., Philipp, Mario T.

“…ABSTRACT Detection of antibody to C 6 , a peptide that reproduces the sequence of the sixth invariable region within the central domain of the VlsE protein of…”
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C 6 Test as an Indicator of Therapy Outcome for Patients with Localized or Disseminated Lyme Borreliosis by Philipp, Mario T., Marques, Adriana R., Fawcett, Paul T., Dally, Leonard G., Martin, Dale S.

“…ABSTRACT Management of Lyme disease would benefit from a test to assess therapy outcome. Such a test could be employed to ascertain if treatment of early Lyme…”
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Borrelia burgdorferi Spirochetes That Harbor Only a Portion of the lp28-1 Plasmid Elicit Antibody Responses Detectable with the C sub(6) Test for Lyme Disease by Embers, Monica E, Wormser, Gary P, Schwartz, Ira, Martin, Dale S, Philipp, Mario T

“…Detection of antibody to C sub(6), a peptide that reproduces the sequence of the sixth invariable region within the central domain of the VlsE protein of…”
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A rhesus macaque model of Streptococcus pneumoniae carriage by Philipp, M.T., Doyle, L.A., Martin, D.S., Plauché, G.B., Phillippi-Falkenstein, K.M., Bohm Jr, R.P

“…Background  Nasopharyngeal colonization by Streptococcus pneumoniae precedes pneumococcal disease. Elucidation of procedures to prevent or eradicate…”
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