Search Results - "Martin, Christopher M"

Linaclotide Inhibits Colonic Nociceptors and Relieves Abdominal Pain via Guanylate Cyclase-C and Extracellular Cyclic Guanosine 3′,5′-Monophosphate by Castro, Joel, Harrington, Andrea M, Hughes, Patrick A, Martin, Christopher M, Ge, Pei, Shea, Courtney M, Jin, Hong, Jacobson, Sarah, Hannig, Gerhard, Mann, Elizabeth, Cohen, Mitchell B, MacDougall, James E, Lavins, Bernard J, Kurtz, Caroline B, Silos-Santiago, Inmaculada, Johnston, Jeffrey M, Currie, Mark G, Blackshaw, L. Ashley, Brierley, Stuart M

“…Background & Aims Linaclotide is a minimally absorbed agonist of guanylate cyclase-C (GUCY2C or GC-C) that reduces symptoms associated with irritable bowel…”
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The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli by Brierley, Stuart M, Hughes, Patrick A, Page, Amanda J, Kwan, Kelvin Y, Martin, Christopher M, O'Donnell, Tracey A, Cooper, Nicole J, Harrington, Andrea M, Adam, Birgit, Liebregts, Tobias, Holtmann, Gerald, Corey, David P, Rychkov, Grigori Y, Blackshaw, L. Ashley

“…Background & Aims The transient receptor potential (TRP) channel family includes transducers of mechanical and chemical stimuli for visceral sensory neurons…”
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Protein Interactions Studied by SAXS:  Effect of Ionic Strength and Protein Concentration for BSA in Aqueous Solutions by Zhang, Fajun, Skoda, Maximilian W. A, Jacobs, Robert M. J, Martin, Richard A, Martin, Christopher M, Schreiber, Frank

“…We have studied a series of samples of bovine serum albumin (BSA) solutions with protein concentration, c, ranging from 2 to 500 mg/mL and ionic strength, I,…”
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Finite-Element Limit Analysis of Mohr–Coulomb Materials in 3D Using Semidefinite Programming by Martin, Christopher M, Makrodimopoulos, Athanasios

“…Semidefinite programming (SDP) provides a convenient framework for the solution of optimization problems involving the eigenvalues of symmetric matrices. The…”
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Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia by Sipe, Walter E B, Brierley, Stuart M, Martin, Christopher M, Phillis, Benjamin D, Cruz, Francisco Bautista, Grady, Eileen F, Liedtke, Wolfgang, Cohen, David M, Vanner, Stephen, Blackshaw, L Ashley, Bunnett, Nigel W

“…Protease-activated receptor (PAR(2)) is expressed by nociceptive neurons and activated during inflammation by proteases from mast cells, the intestinal lumen,…”
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Magnetically Actuated Single-Walled Carbon Nanotubes by Roberts, Samantha P, Barnard, Arthur W, Martin, Christopher M, Blees, Melina K, Alden, Jonathan S, Ruyack, Alexander R, McEuen, Paul L

“…We couple magnetic tweezer techniques with standard lithography methods to make magnetically actuated single-walled carbon nanotube (SWNT) devices. Parallel…”
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Strength predictions of clear wood at multiple scales using numerical limit analysis approaches by Li, Mingjing, Füssl, Josef, Lukacevic, Markus, Eberhardsteiner, Josef, Martin, Christopher M.

“…•Tsai-Wu failure criterion and periodic boundary conditions are implemented.•Annual ring scale and clear wood scale of spruce are considered in…”
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Structural models of metastable phases occurring during the crystallization process of saturated/unsaturated triacylglycerols by Mykhaylyk, Oleksandr O., Smith, Kevin W., Martin, Christopher M., Ryan, Anthony J.

“…Isothermal crystallizations of saturated and mixed saturated/unsaturated triacylglycerols (TAGs) have been studied by simultaneous time‐resolved small‐angle…”
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Rate effects on the uplift capacity of pipelines embedded in clay: Finite element modelling by Sheil, Brian B., Byrne, Byron W., Martin, Christopher M.

“…This paper describes a finite element study of the uplift behaviour of a plane strain pipe segment embedded in modified Cam clay soil. The primary aim of this…”
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Critical Skirt Spacing for Shallow Foundations under General Loading by Mana, Divya S. K, Gourvenec, Susan, Martin, Christopher M

“…AbstractFinite-element limit analysis is used to identify the critical internal skirt spacing for the undrained failure of shallow skirted foundations under…”
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A novel role for TRPM8 in visceral afferent function by Harrington, Andrea M., Hughes, Patrick A., Martin, Christopher M., Yang, Jing, Castro, Joel, Isaacs, Nicole J., Ashley Blackshaw, L., Brierley, Stuart M.

“…Transient receptor potential ion channel melastatin subtype 8 (TRPM8) is activated by cold temperatures and cooling agents, such as menthol and icilin…”
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Structure, rheology and shear alignment of Pluronic block copolymer mixtures by Newby, Gemma E., Hamley, Ian W., King, Stephen M., Martin, Christopher M., Terrill, Nicholas J.

“…The structure and flow behaviour of binary mixtures of Pluronic block copolymers P85 and P123 is investigated by small-angle scattering, rheometry and mobility…”
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Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil by Page, Amanda J., Brierley, Stuart M., Martin, Christopher M., Hughes, Patrick A., Blackshaw, L. Ashley

“…The Deg/ENaC family of ion channels, including ASIC1, 2 and 3, are candidate mechanotransducers in visceral and somatic sensory neurons, although each channel…”
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Gold Nanoparticles Decorated with Oligo(ethylene glycol) Thiols:  Protein Resistance and Colloidal Stability by Zhang, Fajun, Skoda, Maximilian W. A, Jacobs, Robert M. J, Zorn, Stefan, Martin, Richard A, Martin, Christopher M, Clark, Graham F, Goerigk, Günter, Schreiber, Frank

“…The interactions between proteins and gold colloids functionalized with protein-resistant oligo(ethylene glycol) (OEG) thiol, HS(CH2)11(OCH2CH2)6OMe (EG6OMe),…”
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The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function by Page, Amanda J., Brierley, Stuart M., Martin, Christopher M., Martinez-Salgado, Carlos, Wemmie, John A., Brennan, Timothy J., Symonds, Erin, Omari, Taher, Lewin, Gary R., Welsh, Michael J., Blackshaw, L. Ashley

“…Background & Aims: Visceral mechanoreceptors are critical for perceived sensations and autonomic reflex control of gastrointestinal function. However, the…”
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Effect of unsaturated acyl chains on structural transformations in triacylglycerols by Mykhaylyk, Oleksandr O, Martin, Christopher M

“…Simultaneous time-resolved small-angle and wide-angle X-ray scattering has been used in the study of the isothermal crystallization behavior, after quenching,…”
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Gold Nanoparticles Decorated with Oligo(ethylene glycol) Thiols: Enhanced Hofmeister Effects in Colloid−Protein Mixtures by Zhang, Fajun, Skoda, Maximilian W. A, Jacobs, Robert M. J, Dressen, Donald G, Martin, Richard A, Martin, Christopher M, Clark, Graham F, Lamkemeyer, Tobias, Schreiber, Frank

“…Oligo(ethylene glycol) (OEG) thiol self-assembled monolayer (SAM) decorated gold nanoparticles (AuNPs) have potential applications in bionanotechnology due to…”
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In situ SAXS studies of the morphological changes of an alumina-zirconia-silicate ceramic during its formation by Winter, Rudolf, Martin, Christopher M., Le Messurier, Daniel

“…Small‐angle X‐ray scattering is used at two energies, one either side of the zirconium K‐edge, to probe the in situ formation of an alumina–zirconia–silicate…”
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Involvement of metabotropic glutamate 5 receptor in visceral pain by Lindström, Erik, Brusberg, Mikael, Hughes, Patrick A., Martin, Christopher M., Brierley, Stuart M., Phillis, Benjamin D., Martinsson, Rakel, Abrahamsson, Christina, Larsson, Håkan, Martinez, Vicente, Blackshaw, L. Ashley

“…Metabotropic glutamate 5 receptor (mGluR5) antagonists are effective in animal models of inflammatory and neuropathic pain. The involvement of mGluR5 in…”
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Do methane seeps support distinct macrofaunal assemblages?: Observations on community structure and nutrition from the northern California slope and shelf by Levin, Lisa A., James, David W., Martin, Christopher M., Rathburn, Anthony E., Harris, Leslie H., Michener, Robert H.

“…Although the conspicuous epifauna of reducing environments are known to exhibit strong morphological, physiological, and nutritional adaptations for life in…”
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