Search Results - "Martin, A Lopez"

Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial by Antonia, Scott J, Prof, López-Martin, José A, MD, Bendell, Johanna, MD, Ott, Patrick A, MD, Taylor, Matthew, MD, Eder, Joseph Paul, MD, Jäger, Dirk, MD, Pietanza, M Catherine, MD, Le, Dung T, MD, de Braud, Filippo, Prof, Morse, Michael A, Prof, Ascierto, Paolo A, MD, Horn, Leora, MD, Amin, Asim, MD, Pillai, Rathi N, MD, Evans, Jeffry, Prof, Chau, Ian, MD, Bono, Petri, MD, Atmaca, Akin, MD, Sharma, Padmanee, Prof, Harbison, Christopher T, PhD, Lin, Chen-Sheng, PhD, Christensen, Olaf, MD, Calvo, Emiliano, Dr

“…Summary Background Treatments for small-cell lung cancer (SCLC) after failure of platinum-based chemotherapy are limited. We assessed safety and activity of…”
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Solar pilot plant scale hydrogen generation by irradiation of Cu/TiO2 composites in presence of sacrificial electron donors by Maldonado, M.I., López-Martín, A., Colón, G., Peral, J., Martínez-Costa, J.I., Malato, S.

“…[Display omitted] •Exhaustive study at solar pilot scale of H2 generation using copper doped TiO2 showing interesting energy efficiency.•Different organic…”
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Efficacy and safety of pembrolizumab for patients with previously treated advanced vulvar squamous cell carcinoma: Results from the phase 2 KEYNOTE-158 study by Shapira-Frommer, Ronnie, Mileshkin, Linda, Manzyuk, Ludmila, Penel, Nicolas, Burge, Matthew, Piha-Paul, Sarina A, Girda, Eugenia, Lopez Martin, Jose A, van Dongen, Marloes G J, Italiano, Antoine, Xu, Lei, Jin, Fan, Norwood, Kevin, Ott, Patrick A

“…Treatment options for advanced vulvar cancer are limited. We evaluated pembrolizumab monotherapy in patients with advanced vulvar squamous cell carcinoma (SCC)…”
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Plitidepsin in adult patients with COVID-19 requiring hospital admission: A long-term follow-up analysis by Varona, Jose F, Landete, Pedro, Paredes, Roger, Vates, Roberto, Torralba, Miguel, Guisado-Vasco, Pablo, Porras, Lourdes, Muñoz, Patricia, Gijon, Paloma, Ancochea, Julio, Saiz, Elena, Meira, Fernanda, Jimeno, Jose M, Lopez-Martin, Jose A, Estrada, Vicente

“…The APLICOV-PC study assessed the safety and preliminary efficacy of plitidepsin in hospitalized adult patients with COVID-19. In this follow-up study…”
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In Vitro Activity of Ramoplanin against Clostridium difficile, Including Strains with Reduced Susceptibility to Vancomycin or with Resistance to Metronidazole by PELAEZ, T, ALCALA, L, ALONSO, R, MARTIN-LOPEZ, A, GARCIA-ARIAS, V, MARIN, M, BOUZA, E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phase I study of weekly kahalalide F as prolonged infusion in patients with advanced solid tumors by Salazar, R., Cortés-Funes, H., Casado, E., Pardo, B., López-Martín, A., Cuadra, C., Tabernero, J., Coronado, C., García, M., Soto Matos-Pita, A., Miguel-Lillo, B., Cullell-Young, M., Iglesias Dios, J. L., Paz-Ares, L.

“…Purpose Kahalalide F (KF) is a dehydroaminobutyric acid-containing peptide from marine origin with activity against several human malignant cell lines. This…”
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Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial by Martin-Broto, Javier, Hindi, Nadia, Grignani, Giovanni, Martinez-Trufero, Javier, Redondo, Andres, Valverde, Claudia, Stacchiotti, Silvia, Lopez-Pousa, Antonio, D'Ambrosio, Lorenzo, Gutierrez, Antonio, Perez-Vega, Herminia, Encinas-Tobajas, Victor, de Alava, Enrique, Collini, Paola, Peña-Chilet, Maria, Dopazo, Joaquin, Carrasco-Garcia, Irene, Lopez-Alvarez, Maria, Moura, David S, Lopez-Martin, Jose A

“…BackgroundSarcomas exhibit low expression of factors related to immune response, which could explain the modest activity of PD-1 inhibitors. A potential…”
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Phase I Study of Dovitinib (TKI258), an Oral FGFR, VEGFR, and PDGFR Inhibitor, in Advanced or Metastatic Renal Cell Carcinoma by ANGEVIN, Eric, LOPEZ-MARTIN, Jose A, KAY, Andrea, ESCUDIER, Bernard, LIN, Chia-Chi, GSCHWEND, Jurgen E, HARZSTARK, Andrea, CASTELLANO, Daniel, SORIA, Jean-Charles, SEN, Paramita, JULIE CHANG, SHI, Michael

“…Signaling through the fibroblast growth factor (FGF) pathway may account for tumor resistance to antiangiogenic therapies targeting the VEGF pathway. Here,…”
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A free but efficient low-voltage class-AB two-stage operational amplifier by Ramirez-Angulo, J., Carvajal, R.G., Galan, J.A., Lopez-Martin, A.

“…A simple and efficient low-voltage two-stage operational amplifier with Class-AB output stage is introduced. It has a large effective output current boosting…”
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Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-small-cell lung cancer by Agulló-Ortuño, M. Teresa, Díaz-García, C. Vanesa, Agudo-López, Alba, Pérez, Carlos, Cortijo, Ana, Paz-Ares, Luis, López-Ríos, Fernando, Pozo, Francisco, de Castro, Javier, Cortés-Funes, Hernán, López Martín, José A.

“…Purpose Signalling through the insulin-like growth factor 1 receptor (IGF-1R) is implicated in carcinogenesis, metastasis, and resistance to cytotoxic cancer…”
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Phase I Clinical and Pharmacokinetic Study of Plitidepsin as a 1-Hour Weekly Intravenous Infusion in Patients with Advanced Solid Tumors by Miguel A. Izquierdo, Angela Bowman, Margarita García, Duncan Jodrell, Marisa Martinez, Beatriz Pardo, Javier Gómez, José A. López-Martin, José Jimeno, José R. Germá, John F. Smyth

“…Purpose: Plitidepsin, given as a 1-hour weekly i.v. infusion for 3 consecutive weeks during a 4-week treatment cycle, was investigated in patients with solid…”
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Low power analog front-end electronics in deep submicrometer CMOS technology based on gain enhancement techniques by Gómez-Galán, J.A., Sánchez-Rodríguez, T., Sánchez-Raya, M., Martel, I., López-Martín, A., Carvajal, R.G., Ramírez-Angulo, J.

“…This paper evaluates the design of front-end electronics in modern technologies to be used in a new generation of heavy ion detectors—HYDE (FAIR,…”
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Phase I Clinical and Pharmacokinetic Study of Kahalalide F in Patients with Advanced Androgen Refractory Prostate Cancer by RADEMAKER-LAKHAI, Jeany M, HORENBLAS, Simon, MEINHARDT, Willem, STOKVIS, Ellen, DE REIJKE, Theo M, JIMENO, José M, LOPEZ-LAZARO, Luis, LOPEZ MARTIN, José A, BEIJNEN, Jos H, SCHELLENS, Jan H. M

“…Purpose: The purpose is to determine the maximum tolerated dose, profile of adverse events, and dose-limiting toxicity of Kahalalide F (KF) in patients with…”
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Randomized Phase II Study of Trabectedin and Doxorubicin Compared With Doxorubicin Alone as First-Line Treatment in Patients With Advanced Soft Tissue Sarcomas: A Spanish Group for Research on Sarcoma Study by Martin-Broto, Javier, Pousa, Antonio López, de Las Peñas, Ramón, García Del Muro, Xavier, Gutierrez, Antonio, Martinez-Trufero, Javier, Cruz, Josefina, Alvarez, Rosa, Cubedo, Ricardo, Redondo, Andrés, Maurel, Joan, Carrasco, Juan A, López-Martin, José A, Sala, Ángeles, Meana, José Andrés, Ramos, Rafael, Martinez-Serra, Jordi, Lopez-Guerrero, José A, Sevilla, Isabel, Balaña, Carmen, Vaz, Ángeles, De Juan, Ana, Alemany, Regina, Poveda, Andrés

“…Doxorubicin and trabectedin are considered active drugs in soft tissue sarcoma (STS). The combination of both drugs was hypothesized to be advantageous and…”
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TNF induced inhibition of Cirbp expression depends on RelB NF-κB signalling pathway by Lopez, Martin A, Meier, Daniel, Wong, W Wei-Lynn, Fontana, Adriano

“…The circadian clock is required for the rhythmic expression of a plethora of genes that orchestrate metabolism, sleep-wake behaviour and the immune response to…”
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Two-Stage OTA With All Subthreshold MOSFETs and Optimum GBW to DC-Current Ratio by Beloso-Legarra, J., Grasso, A. D., Lopez-Martin, A. J., Palumbo, G., Pennisi, S.

“…An approach for the design of two-stage class-AB OTAs with sub-<inline-formula> <tex-math notation="LaTeX">1{\boldsymbol {\mu }}\text{A}…”
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Topical heparin as an effective and safe treatment for patients with capecitabine-induced hand-foot syndrome: results of a phase IIA trial supported by proteomic profiling of skin biopsies by Rodríguez-Garzotto, Analia, Iglesias-Docampo, Lara, Díaz-García, C. Vanesa, Ruppen, Isabel, Ximénez-Embún, Pilar, Gómez, Carlos, Rodríguez-Peralto, J. Luis, de Frutos, Javier Ortiz, Lopez-Martin, Jose A., Grávalos, Cristina, Cortés-Funes, Hernán, Agulló-Ortuño, M. Teresa

“…Background: Hand-foot syndrome (HFS) is a common adverse reaction associated with capecitabine chemotherapy that significantly affects the quality of life of…”
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Low-voltage high-performance voltage-mode and current-mode WTA circuits based on flipped voltage followers by Ramirez-Angulo, J., Ducoudray-Acevedo, G., Carvajal, R.G., Lopez-Martin, A.

“…A new low-voltage CMOS winner-take-all (WTA) circuit is presented. The proposed circuit exhibits a linear increase of complexity with the number of inputs at…”
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Frequency and Clinicopathological Profile Associated with Braf Mutations in Patients with Advanced Melanoma in Spain by Lopez-Martin, Jose A., Arance Fernández, Ana, Ríos-Martín, Juan José, Hernández-Losa, Javier, Alós Hernández, Lucía, Cerezuela Fuentes, Pablo, Ortiz Reina, Sebastián, Ortega Izquierdo, Eugenia, Martí, Rosa M, Soberino García, Jesús, Ferrer Fábrega, Berta, Rodríguez Peralto, José Luis

“…Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with…”
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A new family of very low-voltage analog circuits based on quasi-floating-gate transistors by Ramirez-Angulo, J., Urquidi, C.A., Gonzalez-Carvajal, R., Torralba, A., Lopez-Martin, A.

“…A new family of very low-voltage analog circuits is introduced. These circuits do not show the GB degradation that characterizes other low-voltage approaches…”
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