Search Results - "Martijn, H"

Sialic Acids Sweeten a Tumor's Life by BÜLL, Christian, STOEL, Marieke A, DEN BROK, Martijn H, ADEMA, Gosse J

“…Over four decades ago, specific tumor characteristics were ascribed to the increased expression of sialic acid sugars on the surface of cancer cells, and this…”
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Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies by van den Bijgaart, Renske J. E., Eikelenboom, Dylan C., Hoogenboom, Martijn, Fütterer, Jurgen J., den Brok, Martijn H., Adema, Gosse J.

“…Tumor ablation technologies, such as radiofrequency-, cryo- or high-intensity focused ultrasound (HIFU) ablation will destroy tumor tissue in a minimally…”
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Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity by Büll, Christian, Boltje, Thomas J, Balneger, Natasja, Weischer, Sarah M, Wassink, Melissa, van Gemst, Jasper J, Bloemendal, Victor R, Boon, Louis, van der Vlag, Johan, Heise, Torben, den Brok, Martijn H, Adema, Gosse J

“…Sialic acid sugars on the surface of cancer cells have emerged as potent immune modulators that contribute to the immunosuppressive microenvironment and tumor…”
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Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase by Slotman, Johan A, Paul, Maarten W, Carofiglio, Fabrizia, de Gruiter, H. Martijn, Vergroesen, Tessa, Koornneef, Lieke, van Cappellen, Wiggert A, Houtsmuller, Adriaan B, Baarends, Willy M

“…The recombinase RAD51, and its meiosis-specific paralog DMC1 localize at DNA double-strand break (DSB) sites in meiotic prophase. While both proteins are…”
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Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds by Boonekamp, Jelle J., Mulder, G. A., Salomons, H. Martijn, Dijkstra, Cor, Verhulst, Simon

“…Developmental stressors often have long-term fitness consequences, but linking offspring traits to fitness prospects has remained a challenge. Telomere length…”
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Nephron mass determines the excretion rate of urinary extracellular vesicles by Blijdorp, Charles J., Hartjes, Thomas A., Wei, Kuang‐Yu, Heugten, Martijn H., Bovée, Dominique M., Budde, Ricardo P.J., Wetering, Jacqueline, Hoenderop, Joost G.J., Royen, Martin E., Zietse, Robert, Severs, David, Hoorn, Ewout J.

“…Urinary extracellular vesicles (uEVs) are emerging as non‐invasive biomarkers for various kidney diseases, but it is unknown how differences in nephron mass…”
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Quantitative assessment of fluorescent proteins by Cranfill, Paula J, Sell, Brittney R, Baird, Michelle A, Allen, John R, Lavagnino, Zeno, de Gruiter, H Martijn, Kremers, Gert-Jan, Davidson, Michael W, Ustione, Alessandro, Piston, David W

“…This Analysis provides a head-to-head comparison of >40 monomeric fluorescent proteins in terms of photophysical properties, photostability and performance in…”
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Steering Siglec–Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry by Büll, Christian, Heise, Torben, van Hilten, Niek, Pijnenborg, Johan F. A., Bloemendal, Victor R. L. J., Gerrits, Lotte, Kers‐Rebel, Esther D., Ritschel, Tina, den Brok, Martijn H., Adema, Gosse J., Boltje, Thomas J.

“…Sialic acid sugars that terminate cell‐surface glycans form the ligands for the sialic acid binding immunoglobulin‐like lectin (Siglec) family, which are…”
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Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti‐inflammatory macrophages by Melief, Sara M., Schrama, Ellen, Brugman, Martijn H., Tiemessen, Machteld M., Hoogduijn, Martin J., Fibbe, Willem E., Roelofs, Helene

“…ABSTRACT Multipotent stromal cells (MSC) have been shown to possess immunomodulatory capacities and are therefore explored as a novel cellular therapy. One of…”
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Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice by van Vliet, Danique, Bruinenberg, Vibeke M, Mazzola, Priscila N, van Faassen, Martijn H J R, de Blaauw, Pim, Kema, Ido P, Heiner-Fokkema, M Rebecca, van Anholt, Rogier D, van der Zee, Eddy A, van Spronsen, Francjan J

“…Phenylketonuria (PKU) was the first disorder in which severe neurocognitive dysfunction could be prevented by dietary treatment. However, despite this effect,…”
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Sweet escape: Sialic acids in tumor immune evasion by Büll, Christian, den Brok, Martijn H., Adema, Gosse J.

“…Sialic acids represent a family of sugar molecules derived from neuraminic acid that frequently terminate glycan chains and contribute to many biological…”
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What’s in a name? further classification of patients with apparent idiopathic ventricular fibrillation by van der Ree, Martijn H, Postema, Pieter G

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Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion by Luis, Tiago C., Naber, Brigitta A.E., Roozen, Paul P.C., Brugman, Martijn H., de Haas, Edwin F.E., Ghazvini, Mehrnaz, Fibbe, Willem E., van Dongen, Jacques J.M., Fodde, Riccardo, Staal, Frank J.T.

“…Canonical Wnt signaling has been implicated in the regulation of hematopoiesis. By employing a Wnt-reporter mouse, we observed that Wnt signaling is…”
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A transplantable TH‐MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma by Kroesen, Michiel, Nierkens, Stefan, Ansems, Marleen, Wassink, Melissa, Orentas, Rimas J., Boon, Louis, Brok, Martijn H., Hoogerbrugge, Peter M., Adema, Gosse J.

“…Current multimodal treatments for patients with neuroblastoma (NBL), including anti‐disialoganglioside (GD2) monoclonal antibody (mAb) based immunotherapy,…”
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Mechanical High-Intensity Focused Ultrasound Destruction of Soft Tissue: Working Mechanisms and Physiologic Effects by Hoogenboom, Martijn, Eikelenboom, Dylan, den Brok, Martijn H, Heerschap, Arend, Fütterer, Jurgen J, Adema, Gosse J

“…Abstract The best known method of high-intensity focused ultrasound is thermal ablation, but interest in non-thermal, mechanical destruction is increasing. The…”
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Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation by den Brok, Martijn H., Büll, Christian, Wassink, Melissa, de Graaf, Annemarie M., Wagenaars, Jori A., Minderman, Marthe, Thakur, Mayank, Amigorena, Sebastian, Rijke, Eric O., Schrier, Carla C., Adema, Gosse J.

“…Saponin-based adjuvants (SBAs) are being used in animal and human (cancer) vaccines, as they induce protective cellular immunity. Their adjuvant potency is a…”
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Frequent Use of Antibiotics Is Associated with Colorectal Cancer Risk: Results of a Nested Case–Control Study by Dik, Vincent K., van Oijen, Martijn G. H., Smeets, Hugo M., Siersema, Peter D.

“…Background Microbiotical dysbiosis induced by a Western diet seems to be associated with an increased risk of developing colorectal cancer (CRC). Few other…”
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Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors by Modlich, Ute, Navarro, Susana, Zychlinski, Daniela, Maetzig, Tobias, Knoess, Sabine, Brugman, Martijn H., Schambach, Axel, Charrier, Sabine, Galy, Anne, Thrasher, Adrian J., Bueren, Juan, Baum, Christopher

“…Gene transfer vectors may cause clonal imbalance and even malignant cell transformation by insertional upregulation of proto-oncogenes. Lentiviral vectors (LV)…”
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Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome by Albers, Cornelis A, Paul, Dirk S, Schulze, Harald, Freson, Kathleen, Stephens, Jonathan C, Smethurst, Peter A, Jolley, Jennifer D, Cvejic, Ana, Kostadima, Myrto, Bertone, Paul, Breuning, Martijn H, Debili, Najet, Deloukas, Panos, Favier, Rémi, Fiedler, Janine, Hobbs, Catherine M, Huang, Ni, Hurles, Matthew E, Kiddle, Graham, Krapels, Ingrid, Nurden, Paquita, Ruivenkamp, Claudia A L, Sambrook, Jennifer G, Smith, Kenneth, Stemple, Derek L, Strauss, Gabriele, Thys, Chantal, van Geet, Chris, Newbury-Ecob, Ruth, Ouwehand, Willem H, Ghevaert, Cedric

“…Cornelis Albers, Cedric Ghevaert and colleagues report that a majority of thrombocytopenia with absent radii (TAR) syndrome cases are caused by compound…”
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Geomagnetic secular variation and the statistics of palaeomagnetic directions by Deenen, Martijn H. L., Langereis, Cor G., van Hinsbergen, Douwe J. J., Biggin, Andrew J.

“…SUMMARY In this study, we examine the role of palaeosecular variation (PSV) in the use of statistics for palaeomagnetic studies, and we provide new reliability…”
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