Search Results - "Martijn, A.J"

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells by Koppens, Martijn A.J, Bounova, Gergana, Gargiulo, Gaetano, Tanger, Ellen, Janssen, Hans, Cornelissen-Steijger, Paulien, Blom, Marleen, Song, Ji-Ying, Wessels, Lodewyk F.A, van Lohuizen, Maarten

“…Background & Aims The polycomb repressive complex 2 (PRC2) regulates differentiation by contributing to repression of gene expression and thereby stabilizing…”
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Readthrough compounds for nonsense mutations: bridging the translational gap by Spelier, Sacha, van Doorn, Eveline P.M., van der Ent, Cornelis K., Beekman, Jeffrey M., Koppens, Martijn A.J.

“…Approximately 10% of all pathological mutations are nonsense mutations which are responsible for the most severe cases of genetic diseases but for which no…”
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Supramolecular polymer materials bring restorative heart valve therapy to patients by Mes, Tristan, Serrero, Aurelie, Bauer, Hannah S., Cox, Martijn A.J., Bosman, Anton W., Dankers, Patricia Y.W., Meijer, E.W.

“…[Display omitted] The functional restoration of natural tissues in a variety of cardiovascular applications is the main objective of Endogenous Tissue…”
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Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration by Koppens, Martijn A.J., Davis, Hayley, Valbuena, Gabriel N., Mulholland, Eoghan J., Nasreddin, Nadia, Colombe, Mathilde, Antanaviciute, Agne, Biswas, Sujata, Friedrich, Matthias, Lee, Lennard, Wang, Lai Mun, Koelzer, Viktor H., East, James E., Simmons, Alison, Winton, Douglas J., Leedham, Simon J.

“…In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signaling. The bone morphogenetic protein (BMP) pathway has a…”
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Thioamides: Versatile Bonds To Induce Directional and Cooperative Hydrogen Bonding in Supramolecular Polymers by Mes, Tristan, Cantekin, Seda, Balkenende, Dirk W. R., Frissen, Martijn M. M., Gillissen, Martijn A. J., De Waal, Bas F. M., Voets, Ilja K., Meijer, E. W., Palmans, Anja R. A.

“…The amide bond is a versatile functional group and its directional hydrogen‐bonding capabilities are widely applied in, for example, supramolecular chemistry…”
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Femoral Component Revision with Use of Impaction Bone-Grafting and a Cemented Polished Stem: A Concise Follow-up, at Fifteen to Twenty Years, of a Previous Report by te Stroet, Martijn A.J, Gardeniers, Jean W.M, Verdonschot, Nico, Rijnen, Wim H.C, Slooff, Tom J.J.H, Schreurs, B Willem

“…We previously reported our results for thirty-three consecutive femoral component revisions with impaction bone-grafting, performed with the X-change femoral…”
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Mechanical characterization of anisotropic planar biological soft tissues using finite indentation: Experimental feasibility by Cox, Martijn A.J, Driessen, Niels J.B, Boerboom, Ralf A, Bouten, Carlijn V.C, Baaijens, Frank P.T

“…Abstract Heart valve tissue engineering offers a promising alternative for current treatment and replacement strategies, e.g., synthetic or bioprosthetic heart…”
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Lactone Size Dependent Reactivity in Candida Antarctica Lipase B: A Molecular Dynamics and Docking Study by Veld, Martijn A.J, Fransson, Linda, Palmans, Anja R.A, Meijer, E.W, Hult, Karl

“…Size matters: Lactones have extensively been studied as monomers in enzymatic polymerization reactions. Large lactones showed an unexpectedly high reactivity…”
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Tissue-engineered heart valves develop native-like collagen fiber architecture by Cox, Martijn A J, Kortsmit, Jeroen, Driessen, Niels, Bouten, Carlijn V C, Baaijens, Frank P T

“…Creating autologous tissues with on-demand and native-like biomechanical properties is the ultimate challenge in functional heart valve tissue engineering. A…”
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Rehabilitation strategy using enhanced housing environment during neural regeneration by Meek, Marcel F, Koning, Martijn A.J, Nicolai, Jean-Philippe A, Gramsbergen, Albert

“…The influence of an enriched environment on the recovery of nerve function was studied after a sciatic nerve lesion and repair. A sciatic nerve gap of 15 mm…”
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Single-Chain Folding of Polymers for Catalytic Systems in Water by Terashima, Takaya, Mes, Tristan, De Greef, Tom F. A, Gillissen, Martijn A. J, Besenius, Pol, Palmans, Anja R. A, Meijer, E. W

“…Enzymes are a source of inspiration for chemists attempting to create versatile synthetic catalysts. In order to arrive at a polymeric chain carrying catalytic…”
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Orthogonal Self-Assembly in Folding Block Copolymers by Hosono, Nobuhiko, Gillissen, Martijn A. J, Li, Yuanchao, Sheiko, Sergei S, Palmans, Anja R. A, Meijer, E. W

“…We herein report the synthesis and characterization of ABA triblock copolymers that contain two complementary association motifs and fold into single-chain…”
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Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification by Kleeman, Sam O, Koelzer, Viktor H, Jones, Helen Js, Vazquez, Ester Gil, Davis, Hayley, East, James E, Arnold, Roland, Koppens, Martijn Aj, Blake, Andrew, Domingo, Enric, Cunningham, Chris, Beggs, Andrew D, Pestinger, Valerie, Loughrey, Maurice B, Wang, Lai-Mun, Lannagan, Tamsin Rm, Woods, Susan L, Worthley, Daniel, Consortium, S Cort, Tomlinson, Ian, Dunne, Philip D, Maughan, Timothy, Leedham, Simon J

“…Pathological Wnt pathway activation is a conserved hallmark of colorectal cancer. Wnt-activating mutations can be divided into: i) ligand-independent (LI)…”
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Sticky Supramolecular Grafts Stretch Single Polymer Chains by Gillissen, Martijn A. J, Terashima, Takaya, Meijer, E. W, Palmans, Anja R. A, Voets, Ilja K

“…The folding of single polymeric chains into single chain polymeric nanoparticles (SCPNs) is a unique strategy to prepare ordered structures at the nanoscopic…”
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Folding Polymers with Pendant Hydrogen Bonding Motifs in Water: The Effect of Polymer Length and Concentration on the Shape and Size of Single-Chain Polymeric Nanoparticles by Stals, Patrick J. M, Gillissen, Martijn A. J, Paffen, Tim F. E, de Greef, Tom F. A, Lindner, Peter, Meijer, E. W, Palmans, Anja R. A, Voets, Ilja K

“…A set of random copolymers based on a benzene-1,3,5-tricarboxamide functional methacrylate (BTAMA) and oligoethylene glycol methacrylate (oEGMA) with different…”
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Triple Helix Formation in Amphiphilic Discotics: Demystifying Solvent Effects in Supramolecular Self-Assembly by Gillissen, Martijn A. J, Koenigs, Marcel M. E, Spiering, Jolanda J. H, Vekemans, Jef A. J. M, Palmans, Anja R. A, Voets, Ilja K, Meijer, E. W

“…A set of chiral, amphiphilic, self-assembling discotic molecules based on the 3,3′-bis(acylamino)-2,2′-bipyridine-substituted benzene-1,3,5-tricarboxamide…”
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The Coil-to-Globule Transition of Single-Chain Polymeric Nanoparticles with a Chiral Internal Secondary Structure by ter Huurne, Gijs M, Gillissen, Martijn A. J, Palmans, Anja R. A, Voets, Ilja K, Meijer, E. W

“…The intramolecular folding of chiral single polymeric chains into single-chain polymeric nanoparticles (SCPNs) via π-stacking was investigated. To this end,…”
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Hydrogen Bonding Directed Supramolecular Polymerisation of Oligo(Phenylene-Ethynylene)s: Cooperative Mechanism, Core Symmetry Effect and Chiral Amplification by Wang, Feng, Gillissen, Martijn A. J., Stals, Patrick J. M., Palmans, Anja R. A., Meijer, E. W.

“…The design of supramolecular motifs with tuneable stability and adjustable supramolecular polymerisation mechanisms is of crucial importance to precisely…”
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Application of effect-directed analysis to identify mutagenic nitrogenous disinfection by-products of advanced oxidation drinking water treatment by Vughs, D., Baken, K. A., Kolkman, A., Martijn, A. J., de Voogt, P.

“…Advanced oxidation processes are important barriers for organic micropollutants in (drinking) water treatment. It is however known that medium pressure UV/H 2…”
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UV and UV/H 2 O 2 Treatment: The Silver Bullet for By-product and Genotoxicity Formation in Water Production by Martijn, A.J., Kruithof, J.C.

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