Search Results - "Martial, Joseph A"

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy by Halkein, Julie, Tabruyn, Sebastien P, Ricke-Hoch, Melanie, Haghikia, Arash, Nguyen, Ngoc-Quynh-Nhu, Scherr, Michaela, Castermans, Karolien, Malvaux, Ludovic, Lambert, Vincent, Thiry, Marc, Sliwa, Karen, Noel, Agnes, Martial, Joseph A, Hilfiker-Kleiner, Denise, Struman, Ingrid

“…Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the…”
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MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells by Sabatel, Céline, Malvaux, Ludovic, Bovy, Nicolas, Deroanne, Christophe, Lambert, Vincent, Gonzalez, Maria-Luz Alvarez, Colige, Alain, Rakic, Jean-Marie, Noël, Agnès, Martial, Joseph A, Struman, Ingrid

“…MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that regulate gene expression at post-transcriptional level. The recent discovery of the…”
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Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer by Bovy, Nicolas, Blomme, Benoît, Frères, Pierre, Dederen, Stella, Nivelles, Olivier, Lion, Michelle, Carnet, Oriane, Martial, Joseph A, Noël, Agnès, Thiry, Marc, Jérusalem, Guy, Josse, Claire, Bours, Vincent, Tabruyn, Sébastien P, Struman, Ingrid

“…The interaction between tumor cells and their microenvironment is an essential aspect of tumor development. Therefore, understanding how this microenvironment…”
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Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis by Bajou, Khalid, Peng, Hongjun, Laug, Walter E., Maillard, Catherine, Noel, Agnes, Foidart, Jean M., Martial, Joseph A., DeClerck, Yves A.

“…Plasminogen activator inhibitor-1 (PAI-1) paradoxically enhances tumor progression and angiogenesis; however, the mechanism supporting this role is not known…”
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RUNX3, EGR1 and SOX9B form a regulatory cascade required to modulate BMP-signaling during cranial cartilage development in zebrafish by Dalcq, Julia, Pasque, Vincent, Ghaye, Aurélie, Larbuisson, Arnaud, Motte, Patrick, Martial, Joseph A, Muller, Marc

“…The cartilaginous elements forming the pharyngeal arches of the zebrafish derive from cranial neural crest cells. Their proper differentiation and patterning…”
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Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration by Manfroid, Isabelle, Ghaye, Aurélie, Naye, François, Detry, Nathalie, Palm, Sarah, Pan, Luyuan, Ma, Taylur P., Huang, Wei, Rovira, Meritxell, Martial, Joseph A., Parsons, Michael J., Moens, Cecilia B., Voz, Marianne L., Peers, Bernard

“…Recent zebrafish studies have shown that the late appearing pancreatic endocrine cells are derived from pancreatic ducts but the regulatory factors involved…”
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PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin by Bajou, Khalid, Herkenne, Stephanie, Thijssen, Victor L, D'Amico, Salvino, Nguyen, Ngoc-Quynh-Nhu, Bouché, Ann, Tabruyn, Sébastien, Srahna, Mohammed, Carabin, Jean-Yves, Nivelles, Olivier, Paques, Cécile, Cornelissen, Ivo, Lion, Michelle, Noel, Agnès, Gils, Ann, Vinckier, Stefan, Declerck, Paul J, Griffioen, Arjan W, Dewerchin, Mieke, Martial, Joseph A, Carmeliet, Peter, Struman, Ingrid

“…The antiangiogenic and profibrinolytic activities of the N-terminal fragment of prolactin, 16K PRL, are mediated by its binding to the protein PAI-1. The…”
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Zebrafish Sox7 and Sox18 function together to control arterial–venous identity by Pendeville, Hélène, Winandy, Marie, Manfroid, Isabelle, Nivelles, Olivier, Motte, Patrick, Pasque, Vincent, Peers, Bernard, Struman, Ingrid, Martial, Joseph A., Voz, Marianne L.

“…Sox7 and Sox18 are members of the F-subgroup of Sox transcription factors family and are mostly expressed in endothelial compartments. In humans, dominant…”
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Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing by Voz, Marianne L, Coppieters, Wouter, Manfroid, Isabelle, Baudhuin, Ariane, Von Berg, Virginie, Charlier, Carole, Meyer, Dirk, Driever, Wolfgang, Martial, Joseph A, Peers, Bernard

“…Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the…”
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Octarellin VI: using rosetta to design a putative artificial (β/α)8 protein by Figueroa, Maximiliano, Oliveira, Nicolas, Lejeune, Annabelle, Kaufmann, Kristian W, Dorr, Brent M, Matagne, André, Martial, Joseph A, Meiler, Jens, Van de Weerdt, Cécile

“…The computational protein design protocol Rosetta has been applied successfully to a wide variety of protein engineering problems. Here the aim was to test its…”
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The antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation by Nguyen, Ngoc-Quynh-Nhu, Castermans, Karolien, Berndt, Sarah, Herkenne, Stephanie, Tabruyn, Sebastien P, Blacher, Silvia, Lion, Michelle, Noel, Agnes, Martial, Joseph A, Struman, Ingrid

“…Angiogenesis, the formation of new blood vessels from existing vasculature, plays an essential role in tumor growth, invasion, and metastasis. 16K hPRL, the…”
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Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development by Manfroid, Isabelle, Delporte, François, Baudhuin, Ariane, Motte, Patrick, Neumann, Carl J, Voz, Marianne L, Martial, Joseph A, Peers, Bernard

“…In amniotes, the pancreatic mesenchyme plays a crucial role in pancreatic epithelium growth, notably through the secretion of fibroblast growth factors…”
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The HMG-Box Transcription Factor Sox4b Is Required for Pituitary Expression of gata2a and Specification of Thyrotrope and Gonadotrope Cells in Zebrafish by Quiroz, Yobhana, Lopez, Mauricio, Mavropoulos, Anastasia, Motte, Patrick, Martial, Joseph A, Hammerschmidt, Matthias, Muller, Marc

“…The pituitary is a complex gland comprising different cell types each secreting specific hormones. The extensive network of signaling molecules and…”
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Sprouty1, a new target of the angiostatic agent 16K prolactin, negatively regulates angiogenesis by Sabatel, Céline, Cornet, Anne M, Tabruyn, Sébastien P, Malvaux, Ludovic, Castermans, Karolien, Martial, Joseph A, Struman, Ingrid

“…Disorganized angiogenesis is associated with several pathologies, including cancer. The identification of new genes that control tumor neovascularization can…”
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Development of Pure Prolactin Receptor Antagonists by Bernichtein, Sophie, Kayser, Christine, Dillner, Karin, Moulin, Stéphanie, Kopchick, John J., Martial, Joseph A., Norstedt, Gunnar, Isaksson, Olle, Kelly, Paul A., Goffin, Vincent

“…Prolactin (PRL) promotes tumor growth in various experimental models and leads to prostate hyperplasia and mammary neoplasia in PRL transgenic mice. Increasing…”
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Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors by Delporte, François M, Pasque, Vincent, Devos, Nathalie, Manfroid, Isabelle, Voz, Marianne L, Motte, Patrick, Biemar, Frédéric, Martial, Joseph A, Peers, Bernard

“…PAX6 is a transcription factor playing a crucial role in the development of the eye and in the differentiation of the pancreatic endocrine cells as well as of…”
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Prolactin/Growth Hormone-Derived Antiangiogenic Peptides Highlight a Potential Role of Tilted Peptides in Angiogenesis by Nguyen, Ngoc-Quynh-Nhu, Tabruyn, Sebastien P., Lins, Laurence, Lion, Michelle, Cornet, Anne M., Lair, Florence, Rentier-Delrue, Francoise, Brasseur, Robert, Martial, Joseph A., Struman, Ingrid

“…Angiogenesis is a crucial step in many pathologies, including tumor growth and metastasis. Here, we show that tilted peptides exert antiangiogenic activity…”
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Molecular Targeting of Antiangiogenic Factor 16K hPRL Inhibits Oxygen-Induced Retinopathy in Mice by Pan, Hao, Nguyen, Ngoc-Quynh-Nhu, Yoshida, Hiroshi, Bentzien, Frauke, Shaw, Lynn C, Rentier-Delrue, Francoise, Martial, Joseph A, Weiner, Richard, Struman, Ingrid, Grant, Maria B

“…To examine the ability and mechanism of the 16 kDa N-terminal fragment of human prolactin (16K hPRL) in the inhibition of abnormal retinal neovascularization…”
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Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development by Larbuisson, Arnaud, Dalcq, Julia, Martial, Joseph A., Muller, Marc

“…Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf) signaling for early differentiation…”
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The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis by Herkenne, Stéphanie, Paques, Cécile, Nivelles, Olivier, Lion, Michelle, Bajou, Khalid, Pollenus, Thomas, Fontaine, Marie, Carmeliet, Peter, Martial, Joseph A, Nguyen, Ngoc-Quynh-Nhu, Struman, Ingrid

“…In endothelial cells, binding of vascular endothelial growth factor (VEGF) to the receptor VEGFR2 activates multiple signaling pathways that trigger processes…”
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