Search Results - "Martínez‐Lorenzo, María‐José"

Activated Human T Cells Release Bioactive Fas Ligand and APO2 Ligand in Microvesicles by Martinez-Lorenzo, Maria Jose, Anel, Alberto, Gamen, Susana, Monleon, Inmaculada, Lasierra, Pilar, Larrad, Luis, Pineiro, Andres, Alava, Maria A, Naval, Javier

“…Activation-induced cell death is a process by which overactivated T cells are eliminated, thus preventing potential autoimmune attacks. Two known mediators of…”
Get full text

Remodelling of the actin cytoskeleton is essential for replication of intravacuolar Salmonella by Méresse, Stéphane, Unsworth, Kate E., Habermann, Anja, Griffiths, Gareth, Fang, Ferric, Martínez‐Lorenzo, María José, Waterman, Scott R., Gorvel, Jean‐Pierre, Holden, David W.

“…Maturation and maintenance of the intracellular vacuole in which Salmonella replicates is controlled by virulence proteins including the type III secretion…”
Get full text

Essential role of the VirB machinery in the maturation of the Brucella abortus‐containing vacuole by Comerci, Diego J., Martínez‐Lorenzo, Maria José, Sieira, Rodrigo, Gorvel, Jean‐Pierre, Ugalde, Rodolfo A.

“…In epithelial cells, the intracellular pathogen Brucella abortus escapes from the endocytic pathway, exploits the autophagic machinery of the host cell and…”
Get full text

Differential Secretion of Fas Ligand- or APO2 Ligand/TNF-Related Apoptosis-Inducing Ligand-Carrying Microvesicles During Activation-Induced Death of Human T Cells by Monleon, Inmaculada, Martinez-Lorenzo, Maria Jose, Monteagudo, Luis, Lasierra, Pilar, Taules, Marta, Iturralde, Maria, Pineiro, Andres, Larrad, Luis, Alava, Maria Angeles, Naval, Javier, Anel, Alberto

“…Preformed Fas ligand (FasL) and APO2 ligand (APO2L)/TNF-related apoptosis-inducing ligand (TRAIL) are stored in the cytoplasm of the human Jurkat T cell line…”
Get full text

The human melanoma cell line MelJuSo secretes bioactive FasL and APO2L/TRAIL on the surface of microvesicles. Possible contribution to tumor counterattack by Martı́nez-Lorenzo, Marı́a José, Anel, Alberto, Alava, Marı́a A, Piñeiro, Andrés, Naval, Javier, Lasierra, Pilar, Larrad, Luis

“…Tumor cells have developed multiple mechanisms to evade control by the immune system. Tumoral cells expressing Fas ligand (FasL) have been proposed to…”
Get full text

Involvement of APO2 ligand/TRAIL in activation‐induced death of Jurkat and human peripheral blood T cells by Martínez‐Lorenzo, María José, Alava, Maria A., Gamen, Susana, Kim, K. Jin, Chuntharapai, Anan, Piñeiro, Andrés, Naval, Javier, Anel, Alberto

“…The interaction of Fas with Fas ligand (FasL) mediates activation‐induced cell death (AICD) of T hybridomas and of mature T lymphocytes. The TNF/TNF receptor…”
Get full text

Recomendaciones para la creación y el funcionamiento de los bancos de leche materna en España by Calvo, Javier, García Lara, Nadia Raquel, Gormaz, María, Peña, Manuela, Martínez Lorenzo, María José, Ortiz Murillo, Pilar, Brull Sabaté, Josep Maria, Samaniego, Carmen María, Gayà, Antoni

“…Resumen La mejor alimentación para un recién nacido es la leche de su propia madre. En aquellos casos en los que esta no está disponible, especialmente en los…”
Get full text

Recommendations for the creation and operation of maternal milk banks in Spain by Calvo, Javier, García Lara, Nadia Raquel, Gormaz, María, Peña, Manuela, Martínez Lorenzo, María José, Ortiz Murillo, Pilar, Brull Sabaté, Josep Maria, Samaniego, Carmen María, Gayà, Antoni

“…It is widely agreed that the best source of nutrition for the newborn is the milk of their own mothers. In those cases where it is not available, especially in…”
Get full text

Estimated fetal weight percentile as a tool to predict collection of cord blood units with higher cellular content: implications for prenatal selection of cord blood donors by Lin, Xinxin, Torrabadella, Marta, Amat, Lluís, Gómez, Susana, Azqueta, Carmen, Sánchez, Mar, Cuadras, Daniel, Martínez Lorenzo, Maria José, Brull, José María, Gayà, Antoni, Cemborain, Arantxa, Pérez Garcia, Cristina, Arroyo, JoséLuís, Querol, Sergi, Gómez Roig, Maria Dolores

“…BACKGROUND The need for high‐cellular‐content cord blood units (CBUs) for allogenic transplantation is evident to improve clinical outcomes. In our environment…”
Get full text

Unusual intracellular trafficking of Salmonella typhimurium in human melanoma cells by Martínez‐Lorenzo, María José, Méresse, Stéphane, De Chastellier, Chantal, Gorvel, Jean‐Pierre

“…Salmonella spp. are enterobacteria capable of invading and replicating in both professional and non‐professional phagocytes. Here, we investigate the fate of…”
Get full text

Tyrosine phosphorylation of the p85 subunit of phosphatidylinositol 3-kinase correlates with high proliferation rates in sublines derived from the Jurkat leukemia by Martı́nez-Lorenzo, Marı́a José, Anel, Alberto, Monleón, Inmaculada, Sierra, José Juan, Piñeiro, Andrés, Naval, Javier, Alava, Maria A

“…A prominent tyrosine phosphorylated protein of 85 kDa (p85) was detected in highly proliferative sublines derived from the Jurkat T cell leukemia. We undertook…”
Get full text

CD59 cross‐linking induces secretion of APO2 ligand in overactivated human T cells by Monleón, Inmaculada, Martínez‐Lorenzo, María José, Anel, Alberto, Lasierra, Pilar, Larrad, Luis, Piñeiro, Andrés, Naval, Javier, Alava, Maria A.

“…Jurkat cells and the derived TCR / CD3‐defective subline, J.RT3.T3.5 undergo activationinduced cell death (AICD) when stimulated with phytohemagglutinin (PHA)…”
Get full text

Phenotype and chondrogenic differentiation of mesenchymal cells from adipose tissue of different species by Martínez-Lorenzo, María José, Royo-Cañas, María, Alegre-Aguarón, Elena, Desportes, Paula, Castiella, Tomás, García-Álvarez, Felícito, Larrad, Luis

“…Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into several mesoderm lineages. They have been isolated from different tissues,…”
Get full text

Recommendations for the creation and operation of maternal milk banks in Spain by Calvo, Javier, García Lara, Nadia Raquel, Gormaz, María, Peña, Manuela, Martínez Lorenzo, María José, Ortiz Murillo, Pilar, Brull Sabaté, Josep Maria, Samaniego, Carmen María, Gayà, Antoni

“…It is widely agreed that the best source of nutrition for the newborn is the milk of their own mothers. In those cases where it is not available, especially in…”
Get full text

Evaluation of occult hepatitis B infection in tissue donors: a multicenter analysis in Spain by Sánchez Ibáñez, Jacinto, Vilarrodona Serrat, Ana, Seoane Pillado, Teresa, Rodriguez Aierbe, Clara, Villalba Montoro, Rafael, Calvo Benito, Javier, Pevida Lopez, Marta, Fernández Paneque, Sergio, Vuelta Lopez, Elena, Martínez Lorenzo, Maria Jose, González Romero, Manuel, Cañizares Castellanos, Angelina, Sauleda Oliveras, Silvia

“…Traditionally, when antibody to the Hepatitis B core antigen (anti-HBc) and antibody to the Hepatitis B surface antigen (anti-HBs) are positive, the donor is…”
Get full text

Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression by Bosque, Alberto, Pardo, Julián, Martínez‐Lorenzo, Mª José, Iturralde, María, Marzo, Isabel, Piñeiro, Andrés, Alava, Mª Angeles, Naval, Javier, Anel, Alberto

“…A systematic study was undertaken to characterize the role of APO 2 ligand/tumor necrosis factor‐related apoptosis‐inducing ligand (APO2L/TRAIL) and Fas ligand…”
Get full text

Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR‐induced Fas ligand expression by Pardo, Julián, Buferne, Michel, Martínez‐Lorenzo, María‐José, Naval, Javier, Schmitt‐Verhulst, Anne‐Marie, Boyer, Claude, Anel, Alberto

“…CD8+ cytotoxic T lymphocyte (CTL) clones are able to exert both perforin‐ and Fas‐dependent cytotoxicity. We show in the present work that phosphatidylinositol…”
Get full text

Lack of Fas/CD95 surface expression in highly proliferative leukemic cell lines correlates with loss of CtBP/BARS and redirection of the protein toward giant lysosomal structures by MONLEON, Inmaculada, ITURRALDE, Maria, MARTINEZ-LORENZO, Maria José, MONTEAGUDO, Luis, LASIERRA, Pilar, LARRAD, Luis, PINEIRO, Andrés, NAVAL, Javier, ALAVA, Maria Angeles, ANEL, Alberto

“…Fas/CD95 is a type-I membrane glycoprotein, which inducesapoptotic cell death when ligated by its physiological ligand. We generated previously…”
Get full text

Apo2L/TRAIL and immune regulation by Anel, Alberto, Bosque, Alberto, Naval, Javier, Pineiro, Andres, Larrad, Luis, Alava, Maria Angeles, Martinez-Lorenzo, Maria Jose

“…Apo2L/TRAIL is a member of the TNF family, with its receptors DR4 and DR5 containing a death domain. Multiple tumors are sensitive to Apo2L/TRAIL-induced…”
Get full text

Chondrogenic differentiation in femoral bone marrow-derived mesenchymal cells (MSC) from elderly patients suffering osteoarthritis or femoral fracture by García-Álvarez, Felícito, Alegre-Aguarón, Elena, Desportes, Paula, Royo-Cañas, María, Castiella, Tomás, Larrad, Luis, Martínez-Lorenzo, María José

“…Abstract This study analyzed the phenotype and the chondrogenic differentiation of bone marrow-derived MSCs from old patients undergoing knee osteoarthritis or…”
Get full text