Search Results - "Marti, Santiago"
-
1
Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease
Published in Frontiers in cellular neuroscience (06-11-2018)“…The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by…”
Get full text
Journal Article -
2
Antioxidant Effect of Hydroxytyrosol, Hydroxytyrosol Acetate and Nitrohydroxytyrosol in a Rat MPP+ Model of Parkinson’s Disease
Published in Neurochemical research (01-11-2021)“…3,4-Dihydroxyphenyl ethanol, known as hydroxytyrosol (HTy), is a phenylpropanoid found in diverse vegetable species. Several studies have demonstrated that HTy…”
Get full text
Journal Article -
3
Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response
Published in Cell death & disease (27-08-2024)“…Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia nigra pars compacta…”
Get full text
Journal Article -
4
Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
Published in Frontiers in pharmacology (18-08-2021)“…Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the knowledge of risk factors as well as the…”
Get full text
Journal Article -
5
Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system
Published in Neurotoxicology (Park Forest South) (01-06-2012)“…► Mild peripheral inflammation exacerbates damage to dopaminergic neurons. ► The effect of peripheral inflammation is also produced without BBB disruption. ►…”
Get full text
Journal Article -
6
Measurement of Spray Drift with a Specifically Designed Lidar System
Published in Sensors (Basel, Switzerland) (08-04-2016)“…Field measurements of spray drift are usually carried out by passive collectors and tracers. However, these methods are labour- and time-intensive and only…”
Get full text
Journal Article -
7
Regulation of the prefrontal cortical dopamine release by GABAA and GABAB receptor agonists and antagonists
Published in Brain research (10-12-1993)“…The gamma-aminobutyric acid-dopamine (GABA-DA) relationship was studied by intracerebral microdialysis in the prefrontal cortex. Nomifensine (5 microM) was…”
Get more information
Journal Article -
8
Organogel Formation by Coaggregation of Adaptable Amidocarbamates and Their Tetraamide Analogues
Published in Langmuir (19-07-2005)“…Mixtures of derivatives of Hanabusa's bolaamphiphilic amidocarbamates containing two Z-valinyl subunits and aliphatic spacers that range from ethylenic to…”
Get full text
Journal Article -
9
Neurotoxic relationship between dopamine and iron in the striatal dopaminergic nerve terminals
Published in Brain research (06-03-2000)“…The neurotoxic effect of dopamine (DA) and iron(III) on DAergic terminals in striatum has been studied by intracerebral microdialysis technique. Twenty-four…”
Get full text
Journal Article -
10
Effect of intracerebral hydroxytyrosol and its nitroderivatives on striatal dopamine metabolism: A study by in vivo microdialysis
Published in Life sciences (1973) (01-08-2015)“…The natural phenolic oil compound hydroxytyrosol (HTy) is widely studied because of its antioxidant and neuroprotective properties. Nitroderivatives of HTy…”
Get full text
Journal Article -
11
In vivo striatal measurement of hydroxytyrosol, and its metabolite (homovanillic alcohol), compared with its derivative nitrohydroxytyrosol
Published in Neuroscience letters (05-09-2014)“…•In vivo measurement of polyphenols by HPLC with electrochemical detection.•Hydroxytyrosol produces high levels of homovanillic alcohol in the…”
Get full text
Journal Article -
12
Inflammatory bowel disease induces pathological α‐synuclein aggregation in the human gut and brain
Published in Neuropathology and applied neurobiology (01-02-2024)“…Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous system (ENS) and spreads to the brain…”
Get full text
Journal Article -
13
Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2021)“…Apoptotic caspases are thought to play critical roles in elimination of excessive and non-functional synapses and removal of extra cells during early…”
Get full text
Journal Article -
14
Host selection, reproductive biology, host-specific development and mortality of the codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), in apple and pear
Published 01-01-2000“…The biology and behavior of the codling moth, Cydia pomonella (L.), was studied to determine factors responsible for differences in susceptibility to moth…”
Get full text
Dissertation -
15
Reformulating Pro-Oxidant Microglia in Neurodegeneration
Published in Journal of clinical medicine (17-10-2019)“…In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of…”
Get full text
Journal Article -
16
Pheromone-mediated mating disruption of Planococcus ficus (Hemiptera: Pseudococcidae) in Tunisian vineyards: Effect on insect population dynamics
Published in Biológia (01-03-2017)“…The mating disruption technique using Checkmate® VMB-XL pheromone dispensers, in combination with imidacloprid-based insecticide treatments through drip…”
Get full text
Journal Article -
17
Effect of in vivo striatal perfusion of lipopolysaccharide on dopamine metabolites
Published in Neuroscience letters (21-05-2010)“…We have used the microdialysis technique to perfuse different concentrations of LPS in the rat's striatum 24 h after the implantation of a microdialysis probe…”
Get full text
Journal Article -
18
Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures
Published in Neurotoxicology (Park Forest South) (01-03-2014)“…•Neuroinflammation contributes to the infiltration of peripheral immune cells into the brain.•Dopamine plays a role on lymphocytes infiltration.•DA may be…”
Get full text
Journal Article -
19
Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide
Published in Journal of neurochemistry (01-04-2008)“…Anti-inflammatory strategies have attracted much interest for their potential to prevent further deterioration of Parkinson's disease. Recent experimental and…”
Get full text
Journal Article -
20
Striatal ablation of GABAergic neurons prevents the in vivo neuroprotective effect of DCG-IV against the MPP super(+)-induced neurotoxicity on dopaminergic nerve terminals
Published in Neurochemistry international (01-12-2010)“…In previous studies we found that intrastriatal DCG-IV administration, an agonist for group II metabotropic glutamate receptor: (i) protected striatal…”
Get full text
Journal Article