Search Results - "Marthaler, Douglas G."

Serotype and Genotype (Multilocus Sequence Type) of Streptococcus suis Isolates from the United States Serve as Predictors of Pathotype by Estrada, April A, Gottschalk, Marcelo, Rossow, Stephanie, Rendahl, Aaron, Gebhart, Connie, Marthaler, Douglas G

“…is a significant cause of mortality in piglets and growing pigs worldwide. The species contains pathogenic and commensal strains, with pathogenic strains…”
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Evidence of infectivity of airborne porcine epidemic diarrhea virus and detection of airborne viral RNA at long distances from infected herds by Alonso, Carmen, Goede, Dane P, Morrison, Robert B, Davies, Peter R, Rovira, Albert, Marthaler, Douglas G, Torremorell, Montserrat

“…Porcine epidemic diarrhea virus (PEDV) spread rapidly after being diagnosed in the USA in April 2013. In this study we assessed whether PEDV could become…”
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Comparative analysis of Streptococcus suis genomes identifies novel candidate virulence-associated genes in North American isolates by Estrada, April A, Gottschalk, Marcelo, Gebhart, Connie J, Marthaler, Douglas G

“…Streptococcus suis is a significant economic and welfare concern in the swine industry. Pan-genome analysis provides an in-silico approach for the discovery of…”
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A novel RNA-based in situ hybridization to detect Seneca Valley virus in neonatal piglets and sows affected with vesicular disease by Resende, Talita P, Marthaler, Douglas G, Vannucci, Fabio A

“…Seneca Valley virus (SVV) is the causative agent of an emerging vesicular disease in swine, which is clinically indistinguishable from other vesicular diseases…”
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MinION sequencing of Streptococcus suis allows for functional characterization of bacteria by multilocus sequence typing and antimicrobial resistance profiling by Tan, Shaoyuan, Dvorak, Cheryl M.T., Estrada, April A., Gebhart, Connie, Marthaler, Douglas G., Murtaugh, Michael P.

“…In recent years, high-throughput sequencing has revolutionized disease diagnosis by its powerful ability to provide high resolution genomic information. The…”
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Antibody Response to Rotavirus C Pre-Farrow Natural Planned Exposure to Gilts and Their Piglets by Kumar, Deepak, Anderson, Amanda V, Pittman, Jeremy, Springer, Nora L, Marthaler, Douglas G, Mwangi, Waithaka

“…A longitudinal study was conducted to investigate the dynamics of genotype-specific (G6 and P[5]) antibody response to different doses (3, 2 and 1) of…”
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Rotavirus Infection in Swine: Genotypic Diversity, Immune Responses, and Role of Gut Microbiome in Rotavirus Immunity by Kumar, Deepak, Shepherd, Frances K, Springer, Nora L, Mwangi, Waithaka, Marthaler, Douglas G

“…Rotaviruses (RVs) are endemic in swine populations, and all swine herds certainly have a history of RV infection and circulation. Rotavirus A (RVA) and C (RVC)…”
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Longitudinal study of Staphylococcus aureus colonization and infection in a cohort of swine veterinarians in the United States by Sun, Jisun, Yang, My, Sreevatsan, Srinand, Bender, Jeffrey B, Singer, Randall S, Knutson, Todd P, Marthaler, Douglas G, Davies, Peter R

“…People working with pigs are at elevated risk of harboring methicillin resistant S. aureus (MRSA) in their nose, which is attributable to occupational exposure…”
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Pseudocowpox virus infection in an American bison (Bison bison) by Shivanna, Vinay, Cino-Ozuna, A Giselle, Heskett, Cody, Marthaler, Douglas G, Ganta, Charan

“…The present report describes a case of pseudocowpox virus (PCPV) infection in a seven-year-old female bison euthanized due to a history of declining condition…”
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A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials by Gazda, Lawrence S., Collins, James, Lovatt, Archie, Holdcraft, Robert W., Morin, Merribeth J., Galbraith, Daniel, Graham, Melanie, Laramore, Melissa A., Maclean, Christine, Black, John, Milne, Euan W., Marthaler, Douglas G., Vinerean, Horatiu V., Michalak, Michelle M., Hoffer, Deborah, Richter, Steven, Hall, Richard D., Smith, Barry H.

“…Background The use of porcine islets to replace insulin‐producing islet β‐cells, destroyed during the diabetogenic disease process, presents distinct…”
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Proposed virulence-associated genes of Streptococcus suis isolates from the United States serve as predictors of pathogenicity by Estrada, April A, Gottschalk, Marcelo, Rendahl, Aaron, Rossow, Stephanie, Marshall-Lund, Lacey, Marthaler, Douglas G, Gebhart, Connie J

“…There is limited information on the distribution of virulence-associated genes (VAGs) in U.S. Streptococcus suis isolates, resulting in little understanding of…”
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Leveraging a Validated in silico Approach to Elucidate Genotype-Specific VP7 Epitopes and Antigenic Relationships of Porcine Rotavirus A by Shepherd, Frances K., Dvorak, Cheryl M. T., Murtaugh, Michael P., Marthaler, Douglas G.

“…Rotavirus A (RVA) remains one of the most widespread causes of diarrheal disease and mortality in piglets despite decades of research and efforts to boost…”
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Longitudinal study of Senecavirus a shedding in sows and piglets on a single United States farm during an outbreak of vesicular disease by Tousignant, Steven J P, Bruner, Laura, Schwartz, Jake, Vannucci, Fabio, Rossow, Stephanie, Marthaler, Douglas G

“…The study highlights the shedding pattern of Senecavirus A (SVA) during an outbreak of vesicular disease in a sow farm from the South-central Minnesota, USA…”
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Role of Pre-Farrow Natural Planned Exposure of Gilts in Shaping the Passive Antibody Response to Rotavirus A in Piglets by Kumar, Deepak, Anderson Reever, Amanda V, Pittman, Jeremy S, Springer, Nora L, Mallen, Kylynn, Roman-Sosa, Gleyder, Sangewar, Neha, Casey-Moore, Mary C, Bowen, Michael D, Mwangi, Waithaka, Marthaler, Douglas G

“…Natural planned exposure (NPE) remains one of the most common methods in swine herds to boost lactogenic immunity against rotaviruses. However, the efficacy of…”
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Frequency of porcine circovirus 3 detection and histologic lesions in clinical samples from swine in the United States by Yang, Zhen, Marthaler, Douglas G., Rovira, Albert

“…Porcine circovirus 3 (PCV3) is widespread in pigs worldwide. Diverse clinical signs and lesions have been associated with PCV3, but the role of PCV3 as a cause…”
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A porcine enterovirus G associated with enteric disease contains a novel papain-like cysteine protease by Knutson, Todd P, Velayudhan, Binu T, Marthaler, Douglas G

“…Identification of unknown pathogens in pigs displaying enteric illness is difficult due to the large diversity of bacterial and viral species found within…”
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Decline of transmissible gastroenteritis virus and its complex evolutionary relationship with porcine respiratory coronavirus in the United States by Chen, Fangzhou, Knutson, Todd P., Rossow, Stephanie, Saif, Linda J., Marthaler, Douglas G.

“…The epidemiology and genetic diversity of transmissible gastroenteritis virus (TGEV) in the United States (US) was investigated by testing clinical cases for…”
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Longitudinal Surveillance of Porcine Rotavirus B Strains from the United States and Canada and In Silico Identification of Antigenically Important Sites by Shepherd, Frances K, Murtaugh, Michael P, Chen, Fangzhou, Culhane, Marie R, Marthaler, Douglas G

“…Rotavirus B (RVB) is an important swine pathogen, but control and prevention strategies are limited without an available vaccine. To develop a subunit RVB…”
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Genome Characterization of a Pathogenic Porcine Rotavirus B Strain Identified in Buryat Republic, Russia in 2015 by Alekseev, Konstantin P, Penin, Aleksey A, Mukhin, Alexey N, Khametova, Kizkhalum M, Grebennikova, Tatyana V, Yuzhakov, Anton G, Moskvina, Anna S, Musienko, Maria I, Raev, Sergey A, Mishin, Alexandr M, Kotelnikov, Alexandr P, Verkhovsky, Oleg A, Aliper, Taras I, Nepoklonov, Eugeny A, Herrera-Ibata, Diana M, Shepherd, Frances K, Marthaler, Douglas G

“…An outbreak of enteric disease of unknown etiology with 60% morbidity and 8% mortality in weaning piglets occurred in November 2015 on a farm in Buryat…”
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Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage by Lin, Chun-Ming, Hou, Yixuan, Marthaler, Douglas G., Gao, Xiang, Liu, Xinsheng, Zheng, Lanlan, Saif, Linda J., Wang, Qiuhong

“…•An original US PEDV strain PC22A was attenuated via Vero cell culture passages.•Attenuated PEDV PC22A strain elicited protective immunity in pigs.•Genomic…”
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