Search Results - "Martha A. Zeiger"

The RET oncogene in papillary thyroid carcinoma by Prescott, Jason D., Zeiger, Martha A.

“…Papillary thyroid carcinoma (PTC) is the most common form of thyroid cancer, accounting for greater than 80% of cases. Surgical resection, with or without…”
Get full text

Association between age and disease specific mortality in medullary thyroid cancer by Sahli, Zeyad T., Canner, Joseph K., Zeiger, Martha A., Mathur, Aarti

“…The aim of this study was to evaluate the association between age and disease specific mortality (DSM) among adults diagnosed with medullary thyroid cancer…”
Get full text

Thyroid Nodule Molecular Testing: Is It Ready for Prime Time? by Khan, Tahsin M, Zeiger, Martha A

“…Cytologically indeterminate thyroid nodules remain a diagnostic and clinical challenge, and molecular testing has been advocated and advanced as a diagnostic…”
Get full text

Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review by McKelvey, Brittany A., Umbricht, Christopher B., Zeiger, Martha A.

“…Telomerase reverse transcriptase (TERT) is the catalytic subunit of the enzyme telomerase and is essential for telomerase activity. Upregulation of TERT…”
Get full text

miR-126-3p Inhibits Thyroid Cancer Cell Growth and Metastasis, and Is Associated with Aggressive Thyroid Cancer by Xiong, Yin, Kotian, Shweta, Zeiger, Martha A, Zhang, Lisa, Kebebew, Electron

“…Previous studies have shown that microRNAs are dysregulated in thyroid cancer and play important roles in the post-transcriptional regulation of target…”
Get full text

Association Between Treatment of Secondary Hyperparathyroidism and Posttransplant Outcomes by Mathur, Aarti, Sutton, Whitney, Ahn, JiYoon B., Prescott, Jason D., Zeiger, Martha A., Segev, Dorry L., McAdams-DeMarco, Mara

“…Secondary hyperparathyroidism (SHPT) affects nearly all patients on maintenance dialysis therapy. SHPT treatment options have considerably evolved over the…”
Get full text

A Prospective Assessment Defining the Limitations of Thyroid Nodule Pathologic Evaluation by CIBAS, Edmund S, BALOCH, Zubair W, LANMAN, Richard B, MANDEL, Susan J, SINDY, Nicole, STEWARD, David L, ZEIGER, Martha A, HAUGEN, Bryan R, ALEXANDER, Erik K, FELLEGARA, Giovanni, LIVOLSI, Virginia A, RAAB, Stephen S, ROSAI, Juan, DIGGANS, James, FRIEDMAN, Lyssa, KENNEDY, Giulia C, KLOOS, Richard T

“…Clinical management of thyroid neoplasms is based on light microscopic diagnosis, but its accuracy and precision are poorly defined. To assess inter- and…”
Get full text

A Panel of Four miRNAs Accurately Differentiates Malignant from Benign Indeterminate Thyroid Lesions on Fine Needle Aspiration by KEUTGEN, Xavier M, FILICORI, Filippo, ELEMENTO, Olivier, FAHEY, Thomas J, CROWLEY, Michael J, YONGCHUN WANG, SCOGNAMIGLIO, Theresa, HODA, Rana, BUITRAGO, Daniel, COOPER, David, ZEIGER, Martha A, ZARNEGAR, Rasa

“…Indeterminate thyroid lesions on fine needle aspiration (FNA) harbor malignancy in about 25% of cases. Hemi- or total thyroidectomy has, therefore, been…”
Get full text

miR-210 Expression Is Strongly Hypoxia-Induced in Anaplastic Thyroid Cancer Cell Lines and Is Associated with Extracellular Vesicles and Argonaute-2 by Powell, Bonita H, Turchinovich, Andrey, Wang, Yongchun, Gololobova, Olesia, Buschmann, Dominik, Zeiger, Martha A, Umbricht, Christopher B, Witwer, Kenneth W

“…Hypoxia, or low oxygen tension, is frequently found in highly proliferative solid tumors such as anaplastic thyroid carcinoma (ATC) and is believed to promote…”
Get full text

American Association of Clinical Endocrinologists and American Association of Endocrine Surgeons Medical Guidelines for the Management of Adrenal Incidentalomas: executive summary of recommendations by Zeiger, Martha A, Thompson, Geoffrey B, Duh, Quan-Yang, Hamrahian, Amir H, Angelos, Peter, Elaraj, Dina, Fishman, Elliott, Kharlip, Julia

Get more information

Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines by Avin, Brittany A., Wang, Yongchun, Gilpatrick, Timothy, Workman, Rachael E., Lee, Isac, Timp, Winston, Umbricht, Christopher B., Zeiger, Martha A.

“…Telomerase reverse transcriptase (TERT) activation plays an important role in cancer development by enabling the immortalization of cells. TERT regulation is…”
Get full text

Case Report: Nine-year-old with parathyroid adenoma within the piriform sinus by Zenno, Anna, Ramamoorthy, Bhavishya, Hammoud, Dima A, Quezado, Martha, Zeiger, Martha A, Jha, Smita

“…We present the case of a 9-year-old girl who presented with symptomatic hypercalcemia from primary hyperparathyroidism (PHPT). Laboratory results revealed…”
Get full text

Exploring the epigenetic regulation of telomerase reverse transcriptase (TERT) in human cancer cell lines by McKelvey, Brittany A., Zeiger, Martha A., Umbricht, Christopher B.

“…Allelic TERT promoter methylation and transcription scenarios in cancer: 1) biallelic wt; 2) monoallelic mutant; 3) monoallelic wt; 4) amplified mutant. The…”
Get full text

Preoperative Molecular Markers in Thyroid Nodules by Sahli, Zeyad T, Smith, Philip W, Umbricht, Christopher B, Zeiger, Martha A

“…The need for distinguishing benign from malignant thyroid nodules has led to the pursuit of differentiating molecular markers. The most common molecular tests…”
Get full text

BRAF Mutation Predicts a Poorer Clinical Prognosis for Papillary Thyroid Cancer by Xing, Mingzhao, Westra, William H., Tufano, Ralph P., Cohen, Yoram, Rosenbaum, Eli, Rhoden, Kerry J., Carson, Kathryn A., Vasko, Vasily, Larin, Alexandr, Tallini, Giovanni, Tolaney, Sara, Holt, Elizabeth H., Hui, Pei, Umbricht, Christopher B., Basaria, Shehzad, Ewertz, Marge, Tufaro, Anthony P., Califano, Joseph A., Ringel, Matthew D., Zeiger, Martha A., Sidransky, David, Ladenson, Paul W.

“…Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve risk stratification of this cancer. Objective: The objective of…”
Get full text

Malignancy risk and reproducibility associated with atypia of undetermined significance on thyroid cytology by Mathur, Aarti, MD, Najafian, Alireza, MD, Schneider, Eric B., PhD, Zeiger, Martha A., MD, FACS, Olson, Matthew T., MD

“…Background The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) describes several subcategories within atypia of undetermined significance (AUS),…”
Get full text

Thyroidectomy in older adults: an American College of Surgeons National Surgical Quality Improvement Program study of outcomes by Sahli, Zeyad T., Ansari, Ghedak, Gurakar, Merve, Canner, Joseph K., Segev, Dorry, Zeiger, Martha A., Mathur, Aarti

“…The growth of the US geriatric population coupled with the rise in thyroid nodular disease and cancer will result in an increased number of thyroidectomies…”
Get full text

The American Association of Clinical Endocrinologists and American Association of Endocrine Surgeons medical guidelines for the management of adrenal incidentalomas by Zeiger, Martha A, Thompson, Geoffrey B, Duh, Quan-Yang, Hamrahian, Amir H, Angelos, Peter, Elaraj, Dina, Fishman, Elliott, Kharlip, Julia

Get more information

DNA methylation-related vitamin D receptor insensitivity in breast cancer by Marik, Radharani, Fackler, MaryJo, Gabrielson, Edward, Zeiger, Martha A., Sukumar, Saraswati, Stearns, Vered, Umbricht, Christopher B.

“…  Calcitriol (1α, 25(OH)-Vitamin D3) binds to the vitamin D receptor (VDR) and regulates differentiation of the normal mammary gland, may therefore be useful…”
Get full text

The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma by Jara, Sebastian M., BS, Carson, Kathryn A., ScM, Pai, Sara I., MD, PhD, Agrawal, Nishant, MD, Richmon, Jeremy D., MD, Prescott, Jason D., MD, Dackiw, Alan, MD, PhD, Zeiger, Martha A., MD, Bishop, Justin A., MD, Tufano, Ralph P., MD, MBA

“…Background Several studies have reported that concurrent chronic lymphocytic thyroiditis (CLT) with papillary thyroid carcinoma (PTC) is associated with…”
Get full text