Search Results - "Martens, E."

Bioengineering bacterial outer membrane vesicles as vaccine platform by Gerritzen, Matthias J.H., Martens, Dirk E., Wijffels, René H., van der Pol, Leo, Stork, Michiel

“…Outer membrane vesicles (OMVs) are naturally non-replicating, highly immunogenic spherical nanoparticles derived from Gram-negative bacteria. OMVs from…”
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The impact of nitrogen starvation on the dynamics of triacylglycerol accumulation in nine microalgae strains by Breuer, Guido, Lamers, Packo P., Martens, Dirk E., Draaisma, René B., Wijffels, René H.

“…► The dynamics of triacylglycerol accumulation in nine microalgal strains were compared. ► When exposed to nitrogen starvation, four species accumulated over…”
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Metabolic characterization of a CHO cell size increase phase in fed-batch cultures by Pan, Xiao, Dalm, Ciska, Wijffels, René H., Martens, Dirk E.

“…Normally, the growth profile of a CHO cell fed-batch process can be divided into two main phases based on changes in cell concentration, being an exponential…”
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Automation of high CHO cell density seed intensification via online control of the cell specific perfusion rate and its impact on the N-stage inoculum quality by Schulze, Markus, Lemke, Johannes, Pollard, David, Wijffels, Rene H., Matuszczyk, Jens, Martens, Dirk E.

“…•Improvement of conventional CHO seed train strategies.•Precise online N-1 perfusion rate control facilitates process intensification.•Importance of accurate…”
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Effect of light intensity, pH, and temperature on triacylglycerol (TAG) accumulation induced by nitrogen starvation in Scenedesmus obliquus by Breuer, Guido, Lamers, Packo P., Martens, Dirk E., Draaisma, René B., Wijffels, René H.

“…•pH 7 and 27.5°C are the optima for TAG accumulation in Scenedesmus obliquus.•Lower incident light intensities result in higher yields on light.•Highest…”
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Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
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Simultaneous growth and neutral lipid accumulation in microalgae by Klok, Anne J., Martens, Dirk E., Wijffels, René H., Lamers, Packo P.

“…[Display omitted] ► Nitrogen limitation in turbidostats causes a metabolic energy imbalance in microalgae. ► This energy imbalance allows simultaneous cell…”
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Edible oils from microalgae: insights in TAG accumulation by Klok, A.J, Lamers, P.P, Martens, D.E, Draaisma, R.B, Wijffels, R.H

“…Highlights • Microalgal lipids are a promising source of sustainable edible oils. • Improving TAG productivity and TAG content is necessary for economical…”
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First continuous marine sponge cell line established by Hesp, Kylie, van der Heijden, Jans M. E., Munroe, Stephanie, Sipkema, Detmer, Martens, Dirk E., Wijffels, Rene H., Pomponi, Shirley A.

“…The potential of sponge-derived chemicals for pharmaceutical applications remains largely unexploited due to limited available biomass. Although many have…”
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Prognostic association of anxiety post myocardial infarction with mortality and new cardiac events: a meta-analysis by Roest, Annelieke M, Martens, Elisabeth J, Denollet, Johan, de Jonge, Peter

“…To assess the association of anxiety after myocardial infarction (MI) with cardiac prognosis. A meta-analysis of references derived from MEDLINE, EMBASE, and…”
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Dynamics of triacylglycerol and EPA production in Phaeodactylum tricornutum under nitrogen starvation at different light intensities by Remmers, Ilse M, Martens, Dirk E, Wijffels, René H, Lamers, Packo P

“…Lipid production in microalgae is highly dependent on the applied light intensity. However, for the EPA producing model-diatom Phaeodactylum tricornutum, clear…”
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A specific gene-microbe interaction drives the development of Crohn's disease-like colitis in mice by Caruso, R, Mathes, T, Martens, E C, Kamada, N, Nusrat, A, Inohara, N, Núñez, G

“…Bacterial dysbiosis is associated with Crohn's disease (CD), a chronic intestinal inflammatory disorder thought to result from an abnormal immune response…”
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Acute effects of tea consumption on attention and mood by Einöther, Suzanne J, Martens, Vanessa E

“…Tea has historically been associated with mood and performance benefits, such as relaxation and concentration. This review summarizes the research on the acute…”
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Modelling chemical degradation of concrete during leaching with rain and soil water types by Jacques, D., Wang, L., Martens, E., Mallants, D.

“…Percolation of external water through concrete results in the degradation of cement and changes the concrete pore water and solid phase composition. The…”
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Symptom dimensions of post-myocardial infarction depression, disease severity and cardiac prognosis by Martens, E J, Hoen, P W, Mittelhaeuser, M, de Jonge, P, Denollet, J

“…Individual symptoms of post-myocardial infarction (MI) depression may be differentially associated with cardiac prognosis, in which somatic/affective symptoms…”
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Breakthrough in Marine Invertebrate Cell Culture: Sponge Cells Divide Rapidly in Improved Nutrient Medium by Conkling, Megan, Hesp, Kylie, Munroe, Stephanie, Sandoval, Kenneth, Martens, Dirk E., Sipkema, Detmer, Wijffels, Rene H., Pomponi, Shirley A.

“…Sponges (Phylum Porifera) are among the oldest Metazoa and considered critical to understanding animal evolution and development. They are also the most…”
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Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer by Martens-Uzunova, E S, Jalava, S E, Dits, N F, van Leenders, G J L H, Møller, S, Trapman, J, Bangma, C H, Litman, T, Visakorpi, T, Jenster, G

“…Prostate cancer (PCa) is the most frequent male malignancy and the second most common cause of cancer-related death in Western countries. Current clinical and…”
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Selection of chemically defined media for CHO cell fed-batch culture processes by Pan, Xiao, Streefland, Mathieu, Dalm, Ciska, Wijffels, René H., Martens, Dirk E.

“…Two CHO cell clones derived from the same parental CHO BC® cell line and producing the same monoclonal antibody (BC-G, a low producing clone; BC-P, a high…”
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Automatic Quality Assessment of Transperineal Ultrasound Images of the Male Pelvic Region, Using Deep Learning by Camps, S.M., Houben, T., Carneiro, G., Edwards, C., Antico, M., Dunnhofer, M., Martens, E.G.H.J., Baeza, J.A., Vanneste, B.G.L., van Limbergen, E.J., de With, P.H.N., Verhaegen, F., Fontanarosa, D.

“…Ultrasound guidance is not in widespread use in prostate cancer radiotherapy workflows. This can be partially attributed to the need for image interpretation…”
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Idarucizumab for dabigatran reversal: A systematic review and meta-analysis of indications and outcomes by van der Horst, S.F.B., Martens, E.S.L., den Exter, P.L., Bos, M.H.A., van Mens, T.E., Huisman, M.V., Klok, F.A.

“…Idarucizumab has been approved to reverse the anticoagulant effect of dabigatran. However, there is little knowledge of the effectiveness and safety of…”
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