Search Results - "Martello, A L"
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Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations
Published in The Journal of pharmacology and experimental therapeutics (01-05-1992)“…The purpose of this study was to assess the duration of (+-)-3,4-methylenedioxymethamphetamine's (MDMA's) effects on serotonin containing neurons in nonhuman…”
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2
Serotonergic recovery after (+/-)3,4-(methylenedioxy) methamphetamine injury: observations in rats
Published in The Journal of pharmacology and experimental therapeutics (01-03-1993)“…(+/-)-3,4-Methylenedioxymethamphetamine (MDMA) is a recreational drug of abuse which damages serotonin (5-HT) neurons in animals. In monkeys, the damage…”
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3
Dexfenfluramine neurotoxicity in brains of non-human primates
Published in The Lancet (British edition) (14-12-1991)“…Dexfenfluramine, a drug prescribed for appetite suppression, was evaluated in non-human primates for its potential to produce toxic effects on brain serotonin…”
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4
Taxol and Discodermolide Represent a Synergistic Drug Combination in Human Carcinoma Cell Lines
Published in Clinical cancer research (01-05-2000)“…Recently, three natural products have been identified, the epothilones, eleutherobin, and discodermolide, whose mechanism of action is similar to that of Taxol…”
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Regulation of electrolyte transport by nitric oxide in the mouse cecum
Published in European journal of pharmacology (29-05-1998)“…The effect and role of nitric oxide (NO) in the regulation of ion transport in the mouse cecum were investigated. l-arginine, used to increase NO production,…”
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Morphological factors influencing transepithelial conductance in a rabbit model of ileitis
Published in Gastroenterology (New York, N.Y. 1943) (01-07-1995)“…Infection of rabbits with coccidia (Eimeria magna) causes chronic ileal inflammation and diarrhea. Inflamed ileum also shows decreased transmural conductance…”
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The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies
Published in Chemistry & biology (01-09-2001)“…Background: During the past decade, Taxol has assumed an important role in cancer chemotherapy. The search for novel compounds with a mechanism of action…”
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Elevated levels of microtubule destabilizing factors in a taxol-resistant/dependent A549 cell line with an α-tubulin mutation
Published in Cancer research (Chicago, Ill.) (15-03-2003)“…The A549 Taxol-resistant cell lines, A549-T12 and A549-T24, were isolated in our laboratory, and are dependent on Taxol for normal growth. The microtubules in…”
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Identification of protein kinase C-alpha, epsilon and zeta in rabbit ileal enterocytes
Published in Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology (01-07-1994)“…Activation of protein kinase C (PKC) has been shown to regulate electrolyte transport in rabbit small intestine. We investigated the types of PKC isoforms in…”
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