Search Results - "Marta Valente"
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Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial
Published in The Lancet infectious diseases (01-02-2018)“…Infants in the UK were first offered a pneumococcal conjugate vaccine (PCV7) in 2006, given at 2 and 4 months of age and a booster dose at 13 months (2 + 1…”
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Precision medicine: The use of tailored therapy in primary immunodeficiencies
Published in Frontiers in immunology (08-12-2022)“…Primary immunodeficiencies (PID) are rare, complex diseases that can be characterised by a spectrum of phenotypes, from increased susceptibility to infections…”
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Immunogenicity of the UK group B meningococcal vaccine (4CMenB) schedule against groups B and C meningococcal strains (Sched3): outcomes of a multicentre, open-label, randomised controlled trial
Published in The Lancet infectious diseases (01-05-2021)“…The use of the multicomponent meningococcal vaccine 4CMenB in the UK schedule at 2, 4, and 12 months of age has been shown to be 59·1% effective at preventing…”
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Understanding the reactogenicity of 4CMenB vaccine: Comparison of a novel and conventional method of assessing post-immunisation fever and correlation with pre-release in vitro pyrogen testing
Published in Vaccine (17-11-2020)“…•Use of continuous methods for temperature monitoring captured higher number of fever episodes.•4CMenB batches MAT scores did not correlate with fever…”
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Hemophagocytic lymphohistiocytosis in an adolescent with NLRP12 ‐related autoinflammatory disorder—A case report
Published in Pediatric allergy and immunology (01-09-2023)Get full text
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Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis
Published in Nature communications (08-03-2024)“…Many countries continue to experience pertussis epidemics despite widespread vaccination. Waning protection after booster vaccination has highlighted the need…”
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Motivations for paediatric vaccine trial participation
Published in Current controlled trials in cardiovascular medicine (08-09-2023)“…For our study on trial motivations, 110 surveys were sent out and 81 responded (73·6% response rate). P-values are for two-sample t-tests, without a correction…”
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Diagnosis of human leptospirosis: systematic review and meta-analysis of the diagnostic accuracy of the Leptospira microscopic agglutination test, PCR targeting Lfb1, and IgM ELISA to Leptospira fainei serovar Hurstbridge
Published in BMC infectious diseases (07-02-2024)“…Leptospirosis is an underdiagnosed infectious disease with non-specific clinical presentation that requires laboratory confirmation for diagnosis. The…”
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Adjunctive rosiglitazone treatment for severe pediatric malaria: A randomized placebo-controlled trial in Mozambican children
Published in International journal of infectious diseases (01-02-2024)“…We tested the hypothesis that adjunctive rosiglitazone treatment would reduce levels of circulating angiopoietin-2 (Angpt-2) and improve outcomes of Mozambican…”
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Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine
Published in Molecular systems biology (01-11-2020)“…Neisseria meningitidis is a major cause of meningitis and septicaemia. A MenB vaccine (4CMenB) was licensed by the European Medicines Agency in January 2013…”
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Case Report: Patient with deficiency of ADA2 presenting leukocytoclastic vasculitis and pericarditis during infliximab treatment
Published in Frontiers in pediatrics (14-06-2023)“…Deficiency of adenosine deaminase 2 (DADA2), first reported in 2014, is a disease with great phenotypic variability, which has been increasingly reported…”
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Meningioma and breast cancer: survival of patients with synchronous and metachronous meningioma and breast cancer
Published in Journal of neuro-oncology (2018)“…The prognosis of the association between Breast Cancer (BC) and Meningioma (M) is unknown. To evaluate the survival impact of tumor exposure sequence in…”
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Serial lung ultrasounds in pediatric pneumonia in Mozambique and Pakistan
Published in Scientific reports (18-03-2021)“…Lung ultrasound (LUS) is a promising point-of-care imaging technology for diagnosing and managing pneumonia. We sought to explore serial LUS examinations in…”
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Plastid genomes of two brown algae, Ectocarpus siliculosus and Fucus vesiculosus: further insights on the evolution of red-algal derived plastids
Published in BMC evolutionary biology (16-10-2009)“…Heterokont algae, together with cryptophytes, haptophytes and some alveolates, possess red-algal derived plastids. The chromalveolate hypothesis proposes that…”
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Recurrent pyogenic infections caused by a novel Gln1420 mutation in the C3 gene
Published in Frontiers in pediatrics (05-10-2022)“…C3 is a crucial protein of the complement system. Congenital C3 deficiency is extremely rare and manifests through recurrent, severe infections and should…”
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Rapid Influenza Testing in Infants and Children Younger than 6 Years in Primary Care: Impact on Antibiotic Treatment and Use of Health Services
Published in The Pediatric infectious disease journal (01-08-2019)“…Influenza is often misdiagnosed in children because of the low sensitivity of clinical diagnosis because of nonspecific signs and symptoms. This can be…”
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Child Health and Mortality Prevention Surveillance (CHAMPS): Manhiça site description, Mozambique
Published in Gates open research (2023)“…The Manhiça Health Research Centre (Manhiça HDSS) was established in 1996 in Manhiça, a rural district at Maputo Province in the southern part of Mozambique…”
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Sarcopenia prevalence and association with nutritional status in cohort of elderly patients affected by musculoskeletal concerns: a real-life analysis
Published in Frontiers in endocrinology (Lausanne) (26-06-2023)“…The progressive loss of skeletal muscle mass, strength, and function that frequently occurs as people get older is referred to as sarcopenia. Elderly…”
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Lung ultrasound patterns in paediatric pneumonia in Mozambique and Pakistan
Published in ERJ open research (01-01-2021)“…Improved pneumonia diagnostics are needed, particularly in resource-constrained settings. Lung ultrasound (LUS) is a promising point-of-care imaging technology…”
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