Search Results - "Martínková, Jiřina"

Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis by PaÅízková, Renata Äerná, Martínková, JiÅina, Havel, Eduard, Safránek, Petr, KaÅ¡ka, Milan, Astapenko, David, BezouÅ¡ka, Jan, Chládek, Jaroslav, Äerný, Vladimír

“…Background Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive…”
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Plasmafiltration as an effective method in the removal of circulating pegylated liposomal doxorubicin (PLD) and the reduction of mucocutaneous toxicity during the treatment of advanced platinum-resistant ovarian cancer by Kubeček, Ondřej, Martínková, Jiřina, Chládek, Jaroslav, Bláha, Milan, Maláková, Jana, Hodek, Miroslav, Špaček, Jiří, Filip, Stanislav

“…Purpose The present study evaluates the safety and efficacy of double-plasma filtration (PF) to remove the exceeding pegylated liposomal doxorubicin (PLD) in…”
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Therapeutic Apheresis, Circulating PLD, and Mucocutaneous Toxicity: Our Clinical Experience through Four Years by Filip, Stanislav, Kubeček, Ondřej, Špaček, Jiří, Lánská, Miriam, Bláha, Milan

“…Cancer treatment has been greatly improved by the combined use of targeted therapies and novel biotechnological methods. Regarding the former, pegylated…”
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A pilot study on pharmacokinetic/pharmacodynamic target attainment in critically ill patients receiving piperacillin/tazobactam by Martínková, Jiřina, Malbrain, Manu L N G, Havel, Eduard, Šafránek, Petr, Bezouška, Jan, Kaška, Milan

“…In critically ill patients, multi-trauma and intensive therapy can influence the pharmacokinetics (PK) and pharmacodynamics (PD) of antibiotics with…”
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Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer by Grim, Jiří, Miloš, Hroch, Jaroslav, Chládek, Jiří, Petera, Jiřina, Martínková

“…Background and Purpose This study estimated patients’ early response following neoadjuvant chemoradiotherapy (CHRT) of locally advanced rectal cancer based on…”
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Plasmafiltration as a possible contributor to kinetic targeting of pegylated liposomal doxorubicin (PLD) in order to prevent organ toxicity and immunosuppression by Martínková, Jiřina, Bláha, Milan, Kubeček, Ondřej, Maláková, Jana, Špaček, Jiří, Bezouška, Jan, Krulichová, Iva Selke, Filip, Stanislav

“…Purpose To examine the removal of pegylated liposomal doxorubicin (PLD) during plasmafiltration (PF) and determine whether the drug could be withheld prior to…”
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Current view of vancomycin in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections by Martínková, Jiřina

“…The review article interprets recommendations for treating methicillin-resistant Staphylococcus aureus (MRSA) infections with vancomycin. These stem from a…”
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Tolerability and Outcomes of Kinetically Guided Therapy With Gentamicin in Critically Ill Neonates During the First Week of Life: An Open-Label, Prospective Study by Martínková, Jirina, MD, PhD, Pokorná, Pavla, MD, Záhora, Jiri, PhD, Chládek, Jaroslav, PhD, Vobruba, Václav, MD, Selke-Krulichová, Iva, PhD, Chládková, Jirina, MD

“…Background Aminoglycosides are bactericidal antibiotics used worldwide for the treatment of serious infections in critically ill patients, including neonates…”
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Pharmacokinetics and pharmacodynamics of methotrexate in non-neoplastic diseases by GRIM, Jiri, CHLADEK, Jaroslav, MARTINKOVA, Jirina

“…Low dose pulse methotrexate (LDMTX) therapy has become effective in the treatment of autoimmune and lymphoproliferative diseases. The pharmacokinetics of LDMTX…”
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Steady-state bioequivalence studies of two memantine tablet and oral solution formulations in healthy volunteers by Chládek, Jaroslav, Žaludek, Bořek, Sova, Petr, Franc, Aleš, Šišpera, Luděk, Martínková, Jiřina, Mičuda, Stanislav, Cermanová, Jolana

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The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis by Chládek, Jaroslav, Simková, Marie, Vanecková, Jaroslava, Hroch, Milos, Chládkova, Jirina, Martínková, Jirina, Vávrová, Jaroslava, Beránek, Martin

“…Objective We assessed the effect of folic acid (FA) on the pharmacokinetics and pharmacodynamics of low-dose oral methotrexate (MTX) during the…”
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Erratum to: Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer by Grim, Jiří, Hroch, Miloš, Chládek, Jaroslav, Petera, Jiří, Martínková, Jiřina

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Model Systems Based on Experimental Animals for Studies on Drug Metabolism in Man: (Mini)Pig Cytochromes P450 3A29 and 2E1 by Anzenbacherová, Eva, Baranová, Jana, Zuber, Roman, Pěchová, Alena, Anzenbacher, Pavel, Souček, Pavel, Martínková, Jiřina

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Proteome Mining of Human Follicular Fluid Reveals a Crucial Role of Complement Cascade and Key Biological Pathways in Women Undergoing in Vitro Fertilization by Jarkovska, Karla, Martinkova, Jirina, Liskova, Lucie, Halada, Petr, Moos, Jiri, Rezabek, Karel, Gadher, Suresh Jivan, Kovarova, Hana

“…In vitro fertilization (IVF) is fraught with problems and currently proteomics approaches are being tried out to examine the microenvironment of the follicle…”
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Influence of CYP3A metabolizer status on the pharmacokinetics and pharmacodynamics of amiodarone by Micuda, S, Hodac, M, Parízek, P, Pleskot, M, Sispera, L, Cerman, J, Maláková, J, Martínková, J, Pidrman, V

“…The present work was designed to determine whether the individual differences in pharmacokinetics and pharmacodynamics of amiodarone and its N-desethyl…”
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Meropenem Pharmacokinetics in the Newborn by VAN DEN ANKER, John N, POKOMA, Pavla, KINZIG-SCHIPPERS, Martina, MARTINKOVA, Jirina, DE GROOT, Ronald, DRUSANO, G. L, SORGEL, Fritz

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Covariate determinants of effective dosing regimens for time-dependent beta-lactam antibiotics for critically ill patients by Kaska, Milan, Havel, Eduard, Selke-Krulichova, Iva, Safranek, Petr, Bezouska, Jan, Martinkova, Jirina

“…Critically ill patients undergoing aggressive fluid resuscitation and treated empirically with hydrosoluble time-dependent beta-lactam antibiotics are at risk…”
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Challenges in cancer research and multifaceted approaches for cancer biomarker quest by Martinkova, Jirina, Gadher, Suresh Jivan, Hajduch, Marian, Kovarova, Hana

“…Recent advances in cancer biology have subsequently led to the development of new molecularly targeted anti-cancer agents that can effectively hit…”
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Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats by Brcakova, Eva, Fuksa, Leos, Cermanova, Jolana, Kolouchova, Gabriela, Hroch, Milos, Hirsova, Petra, Martinkova, Jirina, Staud, Frantisek, Micuda, Stanislav

“…Methotrexate (MTX), an important anticancer and immunosuppressive agent, has been suggested for the treatment of primary biliary cirrhosis. However, the drug's…”
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A Rat Model of Early Sepsis: Relationships between Gentamicin Pharmacokinetics and Systemic and Renal Effects of Bacterial Lipopolysaccharide Combined with Interleukin-2 by Studena, Sarka, Martinkova, Jirina, Slizova, Dasa, Krs, Otakar, Senkerik, Marian, Springer, Drahomira, Chládek, Jaroslav

“…A rat model of early sepsis induced by lipopolysaccharide (LPS) combined with interleukin-2 (IL-2) was developed. The primary aim was to assess the…”
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