Search Results - "Martínez Brito, Dayamin"
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Quantification of thyroid hormones and analogs by liquid chromatography coupled to mass spectrometry. Preliminary results in athletes and non‐athletes serum samples
Published in Drug testing and analysis (01-08-2022)“…This paper aimed to assess a method to measure eight thyroid‐related compounds in serum by liquid chromatography‐mass spectrometry (LC‐MS/MS), to verify the…”
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2
Thyroid metabolism and supplementation: A review framed in sports environment
Published in Drug testing and analysis (01-07-2022)“…Objectives This paper aimed to consider those features that may suggest a link between thyroid hormones pharmacology and athletes' health based on current…”
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3
Effect of thyroid hormones administration on urinary endogenous steroid profile of the athlete biological passport
Published in Drug testing and analysis (01-11-2023)“…This work focused on the possible alterations of the markers of the steroidal module of the athlete biological passport, considering samples of athletes…”
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4
LC‐HRMS‐based metabolomics workflow: An alternative strategy for metabolite identification in the antidoping field
Published in Rapid communications in mass spectrometry (30-07-2023)“…Rationale The proposed metabolomic workflow, based on coupling high‐resolution mass spectrometry with computational tools, can be an alternative strategy for…”
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5
Detection of urinary metabolites of arimistane in humans by gas chromatography coupled to high‐accuracy mass spectrometry for antidoping analyses
Published in Rapid communications in mass spectrometry (30-12-2019)“…Rationale The selection of the most appropriate metabolites of the substances included in the Prohibited List of the World Anti‐Doping Agency (WADA) is…”
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6
Investigation of the Physiological and Post‐training Effects of Ecdysteroid Supplementation by Multivariate Analysis of the Human Serum Metabolome
Published in Journal of chemometrics (01-11-2024)“…ABSTRACT This work aims to characterize the serum profile of athletes after the administration of ecdysteroids, natural steroid hormones recently reported to…”
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7
A further insight into methyltestosterone metabolism: New evidences from in vitro and in vivo experiments
Published in Rapid communications in mass spectrometry (15-10-2020)“…Rationale Although the metabolism of methyltestosterone (MT) has been extensively studied since the 1950s using different techniques, the aim of this study was…”
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8
Detection of urinary arimistane metabolites in humans using liquid chromatography–mass spectrometry: Complementary results to gas chromatography mass spectrometric data and its application to antidoping analyses
Published in Rapid communications in mass spectrometry (30-06-2021)“…Rationale The metabolism of arimistane (Arim) was first described in 2015, and androst‐3,5‐diene‐7β‐ol‐17‐one was proposed as the main metabolite excreted in…”
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9
Mass spectrometric analysis of 7‐oxygenated androst‐5‐ene structures. Influence in trimethylsilyl derivative formation
Published in Rapid communications in mass spectrometry (15-09-2020)“…Rationale Several authors have described the generation of androsta‐3,5‐diene‐7‐one structures from androst‐5‐ene‐3,7‐dione or androst‐5‐ene‐3β‐ol‐7‐one under…”
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10
Arimistane: Degradation product or metabolite of 7‐oxo‐DHEA?
Published in Drug testing and analysis (01-07-2021)“…Rationale The instability of androst‐5‐ene‐3,7‐dione structures under acidic conditions is known. The formation of arimistane from 7‐oxo‐DHEA, influenced by…”
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11
7‐keto‐DHEAmetabolism in humans. Pitfalls in interpreting the analytical results in the antidoping field
Published in Drug testing and analysis (01-11-2019)“…7‐keto‐DHEA (3β‐hydroxy‐androst‐5‐ene‐7,17‐dione) is included in section S1 of the World Antidoping Agency (WADA) List of Prohibited Substances. The detection…”
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12
Correction of the urinary testosterone to epitestosterone ratio measurement in antidoping analyses by chromatographic and mass spectrometric techniques
Published in Drug testing and analysis (01-11-2023)“…The ratio of testosterone (T) to epitestosterone (E) determined in urine samples is the main biomarker used to prove T and precursors abused by athletes…”
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13
Carbon isotope ratio of endogenous urinary steroids of the Cuban population of athletes studied for doping purposes
Published in Drug testing and analysis (01-10-2020)“…The aim of this work was to validate the gas chromatography/combustion/isotope ratio mass spectrometry method in Havana Antidoping Laboratory and verify its…”
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14
Detection of thyroid hormones in urine by liquid chromatography coupled to tandem mass spectrometry
Published in Drug testing and analysis (22-07-2024)“…Recently, the trend of thyroid hormones (TH) consumption in the sports community has been published. It is known the capacity of the exogenously administered…”
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15
Simultaneous quantification of endogenous biomarkers and detection of testosterone esters in human serum using gas chromatography–high‐resolution mass spectrometry
Published in Rapid communications in mass spectrometry (30-03-2024)“…Rationale High‐resolution mass spectrometry (HRMS) has been demonstrated to be an alternative platform for quantitative analyses, identifying unknown compounds…”
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16
Characterization of the thyroid hormones level in urine by liquid chromatography coupled to mass spectrometry focus in the antidoping field
Published in Drug testing and analysis (24-08-2024)“…This paper aims to study the metabolism of thyroid hormones (TH) in urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The method was applied…”
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17
Metabolomics workflow as a driven tool for rapid detection of metabolites in doping analysis. Development and validation
Published in Rapid communications in mass spectrometry (30-01-2022)“…Rationale This work demonstrates the high potential of combining high‐resolution mass spectrometry with chemometric tools, using metabolomics as a guided tool…”
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18
Low‐energy electron ionization optimization for steroidomics analysis using high‐resolution mass spectrometry
Published in Rapid communications in mass spectrometry (15-12-2021)“…Rationale Systematic electron ionization fragmentation studies of steroids have been performed to elucidate and trace their characteristic fragmentation…”
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19
Optimization of a method to detect levothyroxine and related compounds in serum and urine by liquid chromatography coupled to triple quadrupole mass spectrometry
Published in Journal of pharmacological and toxicological methods (01-05-2022)“…Thyroid hormones and their derivatives are structurally related to the non-essential amino acid tyrosine (4-hydroxyphenylalanine). However, there are…”
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20
La analítica antidopaje en Cuba
Published in Anales de la Academia de Ciencias de Cuba (01-05-2021)“…RESUMEN La analítica del control del dopaje es considerada ya una rama de las ciencias altamente integradora. En su desarrollo se ha fusionado la química…”
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