Search Results - "Martínez‐Horta, Saul"

Divergent cognitive trajectories in early stage Huntington's disease: A 3‐year longitudinal study by Martínez‐Horta, Saul, Perez‐Perez, Jesús, Oltra‐Cucarella, Javier, Sampedro, Frederic, Horta‐Barba, Andrea, Puig‐Davi, Arnau, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Background and purpose Cognitive impairment is a central feature of Huntington's disease (HD), but it is unclear to what extent more aggressive cognitive…”
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Increased cerebral FDG‐PET uptake in type 1 diabetes patients with impaired awareness of hypoglycaemia by Sampedro, Frederic, Stantonyonge, Nicole, Martínez‐Horta, Saul, Nan, Nicoleta, Camacho, Valle, Chico, Ana

“…Approximately 20% of type 1 diabetes (T1D) patients have an impaired awareness of hypoglyceamia (IAH). IAH represents a risk factor for severe and recurrent…”
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CLU rs11136000 promotes early cognitive decline in Parkinson's disease by Sampedro, Frederic, Marín‐Lahoz, Juan, Martínez‐Horta, Saul, Pérez‐González, Rocío, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Background The C allele of the rs11136000 genetic variant of the clusterin gene has been associated with increased risk of Alzheimer's disease. However, a…”
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Structural and metabolic brain correlates of apathy in Huntington's disease by Martínez‐Horta, Saul, Perez‐Perez, Jesús, Sampedro, Frederic, Pagonabarraga, Javier, Horta‐Barba, Andrea, Carceller‐Sindreu, Mar, Gomez‐Anson, Beatriz, Lozano‐Martinez, Gloria Andrea, Lopez‐Mora, Diego Alfonso, Camacho, Valle, Fernández‐León, Alejandro, Carrió, Ignasi, Kulisevsky, Jaime

“…ABSTRACT Background Apathy is the most prevalent and characteristic neuropsychiatric feature of Huntington's disease. Congruent with the main early…”
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Dopaminergic degeneration induces early posterior cortical thinning in Parkinson's disease by Sampedro, Frederic, Marín-Lahoz, Juan, Martínez-Horta, Saul, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Cognitive decline in Parkinson's disease (PD) is a highly prevalent condition with no effective treatment. Cortical atrophy is thought to promote its…”
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Neurophysiological Evidence of Compensatory Brain Mechanisms in Early-Stage Multiple Sclerosis by López-Góngora, Mariana, Escartín, Antonio, Martínez-Horta, Saul, Fernández-Bobadilla, Ramón, Querol, Luis, Romero, Sergio, Mañanas, Miquel Àngel, Riba, Jordi

“…Multiple sclerosis (MS) is a chronic central nervous system disorder characterized by white matter inflammation, demyelination and neurodegeneration. Although…”
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Apathy in Parkinson's disease: neurophysiological evidence of impaired incentive processing by Martínez-Horta, Saul, Riba, Jordi, de Bobadilla, Ramón Fernández, Pagonabarraga, Javier, Pascual-Sedano, Berta, Antonijoan, Rosa Maria, Romero, Sergio, Mañanas, Miquel Àngel, García-Sanchez, Carmen, Kulisevsky, Jaime

“…Apathy is one of the most common and debilitating nonmotor manifestations of Parkinson's disease (PD) and is characterized by diminished motivation, decreased…”
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A Randomized Clinical Trial to Evaluate the Effects of Safinamide on Apathetic Non-demented Patients With Parkinson's Disease by Kulisevsky, Jaime, Martínez-Horta, Saul, Campolongo, Antonia, Pascual-Sedano, Berta, Marín-Lahoz, Juan, Bejr-kasem, Helena, Aracil-Bolaños, Ignacio, Horta-Barba, Andrea, Puig-Davi, Arnau, Pagonabarraga, Javier

“…Background Apathy is highly prevalent and disabling in Parkinson's disease (PD). Pharmacological options for its management lack sufficient evidence. Objective…”
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Reduced striato‐cortical and inhibitory transcallosal connectivity in the motor circuit of Huntington's disease patients by Garcia‐Gorro, Clara, de Diego‐Balaguer, Ruth, Martínez‐Horta, Saul, Pérez‐Pérez, Jesus, Kulisevsky, Jaime, Rodríguez‐Dechicha, Nadia, Vaquer, Irene, Subira, Susana, Calopa, Matilde, Muñoz, Esteban, Santacruz, Pilar, Ruiz‐Idiago, Jesús, Mareca, Celia, Caballol, Nuria, Camara, Estela

“…Huntington's disease (HD) is a neurodegenerative disorder which is primarily associated with striatal degeneration. However, the alterations in connectivity of…”
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Response to letter: “Association of elevated blood homocysteine with cognitive decline in early, untreated Parkinson's disease” by Sampedro, Frederic, Martínez-Horta, Saul, Kulisevsky, Jaime

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Serum neurofilament light chain levels reflect cortical neurodegeneration in de novo Parkinson's disease by Sampedro, Frederic, Pérez-González, Rocío, Martínez-Horta, Saul, Marín-Lahoz, Juan, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Cognitive impairment and dementia are highly prevalent non-motor complications in Parkinson's disease (PD) with deleterious consequences for patients and…”
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Longitudinal intracortical diffusivity changes in de-novo Parkinson's disease: A promising imaging biomarker by Sampedro, Frederic, Martínez-Horta, Saul, Marín-Lahoz, Juan, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Cognitive impairment and dementia in Parkinson's disease (PD) are highly disabling non-motor symptoms with no effective treatment currently available. As…”
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Extrastriatal SPECT-DAT uptake correlates with clinical and biological features of de novo Parkinson's disease by Sampedro, Frederic, Marín-Lahoz, Juan, Martínez-Horta, Saul, Camacho, Valle, Lopez-Mora, Diego-Alfonso, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Striatal dopamine transporter (DAT) uptake assessment through I123-Ioflupane Single-Pphoton Emission Computed Tomography (SPECT) provides valuable information…”
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Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase by Pagonabarraga, Javier, Martinez-Horta, Saul, Fernández de Bobadilla, Ramón, Pérez, Jesús, Ribosa-Nogué, Roser, Marín, Juan, Pascual-Sedano, Berta, García, Carmen, Gironell, Alexandre, Kulisevsky, Jaime

“…Objectives The description of minor hallucinatory phenomena (presence, passage hallucinations) has widened the spectrum of psychosis in Parkinson's disease…”
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A divergent breakdown of neurocognitive networks in Parkinson's Disease mild cognitive impairment by Aracil‐Bolaños, Ignacio, Sampedro, Frederic, Marín‐Lahoz, Juan, Horta‐Barba, Andrea, Martínez‐Horta, Saül, Botí, Mariángeles, Pérez‐Pérez, Jesús, Bejr‐Kasem, Helena, Pascual‐Sedano, Berta, Campolongo, Antonia, Izquierdo, Cristina, Gironell, Alexandre, Gómez‐Ansón, Beatriz, Kulisevsky, Jaime, Pagonabarraga, Javier

“…Cognitive decline is a major disabling feature in Parkinson's disease (PD). Multimodal imaging studies have shown functional disruption in neurocognitive…”
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Disruption of the default mode network and its intrinsic functional connectivity underlies minor hallucinations in Parkinson's disease by Bejr‐kasem, Helena, Pagonabarraga, Javier, Martínez‐Horta, Saül, Sampedro, Frederic, Marín‐Lahoz, Juan, Horta‐Barba, Andrea, Aracil‐Bolaños, Ignacio, Pérez‐Pérez, Jesús, Ángeles Botí, M., Campolongo, Antonia, Izquierdo, Cristina, Pascual‐Sedano, Berta, Gómez‐Ansón, Beatriz, Kulisevsky, Jaime

“…Background Minor hallucinations and well‐structured hallucinations are considered in the severity continuum of the psychotic spectrum associated with…”
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Impaired face-like object recognition in premanifest Huntington's disease by Martínez-Horta, Saul, Horta-Barba, Andrea, Perez-Perez, Jesús, Antoran, Mizar, Pagonabarraga, Javier, Sampedro, Frederic, Kulisevsky, Jaime

“…Progressive striatal atrophy has long been considered the pathological hallmark of Huntington's disease (HD), but is it now recognized that malfunction and…”
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Structural and metabolic brain correlates of arithmetic word‐problem solving in Huntington's disease by Horta‐Barba, Andrea, Martinez‐Horta, Saul, Sampedro, Frederic, Pérez‐Pérez, Jesús, Camacho, Valle, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Individuals with pre‐manifest and early symptomatic Huntington's disease (HD) have shown deficits in solving arithmetic word‐problems. However, the neural…”
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Cortical microstructural correlates of plasma neurofilament light chain in Huntington's disease by Sampedro, Frederic, Pérez-Pérez, Jesus, Martínez-Horta, Saul, Pérez-González, Rocío, Horta-Barba, Andrea, Campolongo, Antonia, Izquierdo, Cristina, Pagonabarraga, Javier, Gómez-Ansón, Beatriz, Kulisevsky, Jaime

“…Huntington's disease (HD) is a severe neurodegenerative disorder with no effective treatment. Minimally-invasive biomarkers such as blood neurofilament light…”
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Structure and Dynamics of Large‐Scale Cognitive Networks in Huntington's Disease by Aracil‐Bolaños, Ignacio, Martínez‐Horta, Saül, González‐de‐Echávarri, Jose M., Sampedro, Frederic, Pérez‐Pérez, Jesús, Horta‐Barba, Andrea, Campolongo, Antonia, Izquierdo, Cristina, Gómez‐Ansón, Beatriz, Pagonabarraga, Javier, Kulisevsky, Jaime

“…Background Huntington's disease is a neurodegenerative disorder characterized by clinical alterations in the motor, behavioral, and cognitive domains. However,…”
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